18 unknown, 16 completed, 7 terminated, 3 withdrawn. 14 Phase 4, 11 Not applicable, 10 Phase 2, 7 Phase 3, 1 Phase 1.
Follow Alprostadil: new trials by email Literature Review of Alprostadil trials Research Report on Alprostadil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ALP-1 Continuous Intravenous Infusion to Maintain Clinical Stability in Advanced Heart Failure Alprostadil - End Stage Cardiac Failure, HFrEF - Heart Failure With Reduced Ejection Fraction | Phase 3 | Not yet recruiting | Biopeutics Co., Ltd | 600 | 2026-10-01 | 2025-12-15 |
| Termination of Pregnancy in Previous Scarred Uterus: PGE1 Versus Cervical Folleys PGE1 tablet, cervical folleys - Termination of Pregnancy | Phase 4 | Completed | Dr Mudassar Saeed Pansota | 60 | 2025-11-13 | 2026-05-22 |
| Intravenous Dexamethasone for Inducing Labor in Women With Term Pregnancy and Pre-Labour Rupture of Membranes Dexamethasone, Prostaglandin E1, Normal Saline - Rupture of Membranes Prior to Onset of Labor, Induction of Labor | Phase 4 | Completed | Nishtar Medical University | 60 | 2025-07-15 | 2026-03-31 |
| Study on the Efficacy of Alprostadil Injection in Patients With Acute Ischemic Stroke Alprostadil, Normal saline - Stroke | Phase 4 | Unknown | The First Hospital of Jilin University | 950 | 2024-04-18 | 2024-04-01 |
| Letrozole in Induction of Abortion of Anembryonic Pregnancy Letrozole tablets, Misoprostol Tabets, Placebo tablets - Anembryonic Pregnancy | Not applicable | Completed | Cairo University | 96 | 2022-04-03 | 2023-09-11 |
| To Study the Efficacy and Safety of Misoprostol by Sublingual Routes for Induction of Labour Misoprostol - Induction of Labour | Not applicable | Unknown | Ministry of Health, Bhutan | 500 | 2021-06-01 | 2021-05-17 |
| Cri Analog PG1 Effectiveness and Safety in Covid-19 Analogs, Prostaglandin E1, Standard therapeutic protocol - Covid19 | Phase 2 | Withdrawn | Alonso Vera Torres | 2020-12-03 | 2023-09-15 | |
| Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage misoprostol - Miscarriage, Misoprostol | Phase 2 | Completed | Islamabad Medical and Dental College | 120 | 2020-11-02 | 2022-05-24 |
| Efficacy of Misoprostol in Prevention of Neonatal Respiratory Morbidity in Parturient at Early Term Elective Caesarian Section Misoprostol, Placebo - Transient Tachypnea of the Newborn, Neonatal Respiratory Distress | Phase 3 | Unknown | Ain Shams University | 210 | 2020-09-01 | 2021-03-03 |
| Alprostadil as an Adjuvant Therapy With Indirect Angiosomal Revascularization in Critical Limb Ischemia. Alprostadil - Critical Limb Ischemia | Phase 4 | Unknown | Assiut University | 30 | 2020-04-01 | 2020-03-20 |
| Labor Induction With Misoprostol Versus Oxytocin in Women With Premature Rupture of Membranes Misoprostol, Oxytocin - Prelabor Rupture of Membranes, Premature Rupture of Membrane | Not applicable | Unknown | sammour.rami | 200 | 2019-12-01 | 2020-01-29 |
| iMeditate at Home for Older Adults With Mild Cognitive Impairment and Caregivers Mindfulness meditation delivered via a mobile app - Mild Cognitive Impairment, Caregivers | Not applicable | Terminated | Baycrest | 9 | 2019-11-15 | 2022-03-02 |
| The Comparative Effectiveness of Alprostadil,Sodium Ferulate and Dopamine in Pediatric Acute Kidney Injury Alprostadil, Sodium Ferulate, Dopamine - Children AKI Patients | Phase 4 | Unknown | Shengjing Hospital | 300 | 2019-08-01 | 2019-03-27 |
| Acute Effects of the Prostaglandin (Alprostadil) on Cerebral and Pulmonary Flow Alprostadil 5 MCG Injection - Congenital Heart Disease | Phase 1 | Terminated | The Hospital for Sick Children | 10 | 2019-07-23 | 2023-02-08 |
| Effects of Prostaglandin E1 Treatment on Pyloric Wall in Newborns Prostaglandin E1 - Pyloric Stenosis;Acquired, Congenital Heart Disease | Unknown | Hacettepe University | 20 | 2019-05-06 | 2020-08-03 | |
| Intra-arterial Prostaglandin Therapy in Non-occlusive Mesenteric Ischemia Prostavasin - Non-Occlusive Mesenteric Ischaemia (NOMI) | Completed | Hannover Medical School | 42 | 2018-10-01 | 2022-03-15 | |
| Comparison of Two Protocols of Misoprostol (PGE1) and the Rate of Cesarean Section Due to Failed Induction. 6 misoprostol, 3 misoprostol - Induction of Labor | Not applicable | Completed | Saint Thomas Hospital, Panama | 310 | 2018-04-05 | 2018-10-12 |
| Evaluation of Nail Fold Microcirculation in CKD Alprostadil Injection, Beraprost sodium tablets - Chronic Renal Disease | Phase 4 | Unknown | The Affiliated Hospital of Xuzhou Medical University | 100 | 2018-02-01 | 2018-09-26 |
| Efficacy of Intracoronary Infusion of Different Medicine in STEMI Patients Undergoing Primary PCI Alprostadil, Nicorandil, Nitroglycerin - ST Segment Elevation Myocardial Infarction | Phase 4 | Unknown | RenJi Hospital | 600 | 2017-09-01 | 2017-08-17 |
| Blood Flow Change After Free Flap Surgery in Diabetic Patients Alprostadil - Diabetes | Completed | Asan Medical Center | 44 | 2017-01-31 | 2018-11-30 |
Showing 20 of 45. Sign in to see all of them.
Erectile Dysfunction (5) · Diabetes Mellitus (2) · Fetal Membranes, Premature Rupture (2) · Heart Defects, Congenital (2) · Hypertension, Pulmonary (2) · Peripheral Arterial Occlusive Disease 1 (2) · Prostatic Neoplasms (2) · Raynaud Disease (2) · Respiratory Distress Syndrome (2) · ST Elevation Myocardial Infarction (2) · Sexual Dysfunction, Physiological (2) · Abortion, Spontaneous (1) · Acute Kidney Injury (1) · Arteriosclerosis Obliterans (1) · COVID-19 (1)
Asan Medical Center (2) · RenJi Hospital (2) · UCB Pharma (2) · Aga Khan University (1) · Ain Shams University (1) · Alonso Vera Torres (1) · Assiut University (1) · Baycrest (1) · Biopeutics Co., Ltd (1) · Cairo University (1) · Christoph Hehrlein (1) · City of Hope Medical Center (1) · Dr Mudassar Saeed Pansota (1) · First Affiliated Hospital, Sun Yat-Sen University (1) · Guangzhou Yipinhong Pharmaceutical CO.,LTD (1)
China (8) · United States (7) · Germany (5) · Canada (3) · Pakistan (3) · Austria (2) · Egypt (2) · Israel (2) · South Korea (2) · Australia (1) · Bhutan (1) · Brazil (1) · Czechia (1) · Mexico (1) · Panama (1)
Ben He, MD,PhD (2) · Allison B Sekuler, PhD (1) · Ashraf Elnaggar, Dr (1) · Asnat Walfisch, MD (1) · Atiqa Noreen (1) · Barbara Troupin, MD, MBA (1) · Bonan Lv (1) · Christopher G. Wood, MD (1) · Dan Liu (1) · Dong Sun, MD (1) · Edward F. Bell, MD (1) · Gang Zhao (1) · Gerald Brock, MD (1)
PMID 10607766, PMID 18783876, PMID 25496504, PMID 28189475, PMID 29728334, PMID 33847683, PMID 35379286, PMID 35426776, PMID 36856877, PMID 36996264
2005 (2), P30CA016672 (1), P50CA090270 (1), U10HD021364 (1), U10HD021385 (1), U10HD027880 (1), U10HD034216 (1), U10HD036790 (1), U10HD040492 (1), U10HD040689 (1), U10HD053089 (1), U10HD053109 (1), U10HD053119 (1), U10HD053124 (1)