200 completed, 34 unknown, 26 terminated, 21 recruiting. 86 Phase 2, 66 Phase 3, 39 Not applicable, 37 Phase 1, 20 Phase 4.
Follow Euglenozoa Infections: new trials by email Literature Review of Euglenozoa Infections trials Research Report on Euglenozoa Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL) Sodium Stibogluconate (SSG), Miltefosine, Miltefosine + Paromomycin - Cutaneous Leihmaniasis | Phase 3 | Not yet recruiting | Institute of Tropical Medicine, Belgium | 900 | 2027-01-01 | 2026-03-10 |
| Immersive Technology Headsets to Reduce Procedural Pain and Anxiety: Feasibility and Effects in Cutaneous Leishmaniasis Patients in Pakistan Virtual Reality - Cutaneous Leishmaniasis, Pain | Not applicable | Not yet recruiting | Stanford University | 15 | 2027-01-01 | 2026-10-05 |
| An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health Nifurtimox (BAYA2502) - Chagas Disease | Not yet recruiting | Bayer | 50 | 2026-12-31 | 2026-07-06 | |
| Assessment of the Risk of Zoonotic Infections in Prisons in French Guiana Q Fever, Leptospirosis | Not yet recruiting | Centre Hospitalier de Cayenne | 450 | 2026-10-01 | 2026-10-19 | |
| Ex Vivo Immunogenicity Screening of Vaccine Candidate Antigen Combinations in Ethiopian Patients With Leishmaniasis Leishmaniasis, Cutaneous, Leishmaniasis | Recruiting | Institute of Tropical Medicine, Belgium | 90 | 2026-05-26 | 2026-08-24 | |
| Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers A mobile app with AI functionality for diagnosing skin-related NTDs - Skin and Connective Tissue Diseases, Neglected Tropical Diseases | Not applicable | Not yet recruiting | Kenya Medical Research Institute | 2420 | 2026-05-01 | 2026-04-02 |
| Arnica Tincture Fot the Treatment of Cutaneous Leishmaniasis II. Arnica Tincture, Meglumine antimoniate. - Leishmaniasis, Cutaneous | Phase 3 | Recruiting | Universidad de Antioquia | 96 | 2026-03-11 | 2026-04-02 |
| Pilot Study: Miltefosine Gel (G-MTF) in Patients With Cutaneous Leishmaniasis MILTEFOSINE gel - Cutaneous Leishmaniasis, Cutaneous Leishmaniasis, American | Phase 1 | Not yet recruiting | Universidad Industrial de Santander | 15 | 2026-01-01 | 2025-09-08 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Recurrent Visceral Leishmaniasis in HIV Co-Infection Hiv, Visceral Leishmaniasis | Recruiting | Institute of Tropical Medicine, Belgium | 20 | 2025-10-21 | 2026-03-23 | |
| First-in-Human Trial of Oral AN2-502998 AN2-502998, Placebo - Healthy Volunteers | Phase 1 | Completed | AN2 Therapeutics, Inc | 72 | 2025-08-04 | 2026-04-30 |
| Human Bioequivalence Study of Liposomal Amphotericin B for Injection Test product (Liposomal amphotericin B for injection, Sichuan Huiyu Pharmaceutical Co., Ltd.), Reference product (AmBisome®, Astellas Pharma US Inc.) - Invasive Fungal Infections, Neutropenic Fever | Not applicable | Completed | Sichuan Huiyu Pharmaceutical Co., Ltd | 58 | 2025-05-25 | 2026-05-27 |
| Human Bioequivalence Study of Amphotericin B Liposome for Injection Amphotericin B Liposome for Injection (strength: 50 mg, Sichuan Huiyu Pharmaceutical Co., Ltd.), Amphotericin B Liposome for Injection (trade name: Ambisome®, strength: 50 mg, MAH: Gilead Sciences) - Invasive Fungal Infections, Neutropenic Fever | Not applicable | Completed | Sichuan Huiyu Pharmaceutical Co., Ltd | 42 | 2025-05-13 | 2026-05-22 |
| A Study of Efficacy, Safety, Tolerability of LXE408 in Participants With Chronic Chagas Disease. LXE408, Placebo, Benznidazole - Chagas Disease | Phase 2 | Recruiting | Novartis Pharmaceuticals | 130 | 2025-04-28 | 2026-11-10 |
| Feasibility of Integrating Thermotherapy for Treatment of Cutaneous Leishmaniasis in Primary Health Care Setup Thermotherapy - Cutaneous Leishmaniasis | Not applicable | Recruiting | Armauer Hansen Research Institute, Ethiopia | 103 | 2025-04-24 | 2026-10-16 |
| Antimicrobial Adjuvants to Revert the Imbalance of Skin Microbiota for Improved Outcomes of Complicated Cutaneous Leishmaniasis Treatment in Ethiopia Fusidic Acid, Vehicle cream - Leishmaniasis, Cutaneous | Phase 3 | Not yet recruiting | Institute of Tropical Medicine, Belgium | 180 | 2025-04-01 | 2024-11-19 |
| Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne Diseases Peripheral venous blood sample - Leishmaniasis, Leptospirosis | Not applicable | Not yet recruiting | University Hospital, Montpellier | 183 | 2025-03-03 | 2025-03-05 |
| Intralesional Injection of Metronidazole for the Management of Cutaneous Leishmaniasis Metronidazole - Cutaneous Leishmaniasis | Phase 2 | Recruiting | Hayder Adnan Fawzi | 40 | 2025-02-10 | 2025-02-14 |
| Intralesional Injection of Levofloxacin for the Management of Cutaneous Leishmaniasis Levofloxacin 0.5% - Cutaneous Leishmaniasis | Phase 2 | Recruiting | Hayder Adnan Fawzi | 40 | 2025-02-09 | 2025-09-30 |
| Ciprofloxacin Intralesional Injection for the Treatment of Cutaneous Leishmaniasis Compared to Sodium Stibogluconate Ciprofloxacin (BAYO9867), sodium stibogluconate (Pentostam) - Cutaneous Leishmaniasis | Phase 2 | Recruiting | Al-Mustafa University College | 80 | 2025-02-07 | 2025-09-30 |
Showing 20 of 302. Sign in to see all of them.
Leishmaniasis, Cutaneous (103) · Chagas Disease (73) · Leishmaniasis (71) · Leishmaniasis, Visceral (61) · Trypanosomiasis, African (22) · Leishmaniasis, Mucocutaneous (21) · Chagas Cardiomyopathy (17) · Heart Failure (10) · Disease (8) · Trypanosomiasis (8) · Infections (7) · Neglected Diseases (7) · Heart Diseases (5) · Hyperthermia (5) · Brucellosis (4)
Protozoan Infections (301) · Parasitic Diseases (298) · Vector Borne Diseases (298) · Infections (295) · Skin Diseases, Infectious (150) · Skin and Connective Tissue Diseases (149) · Skin Diseases (148) · Skin Diseases, Parasitic (147) · Leishmaniasis (129) · Trypanosomiasis (95) · Pathological Conditions, Signs and Symptoms (37) · Pathologic Processes (31) · Cardiovascular Diseases (28) · Heart Diseases (23)
miltefosine (39) · Meglumine Antimoniate (25) · Paromomycin (19) · benzonidazole (19) · liposomal amphotericin B (19) · Antimony Sodium Gluconate (14) · Nifurtimox (13) · fexinidazole (8) · Amphotericin B (7) · Eflornithine (5) · Pentamidine (5) · amphotericin B, deoxycholate drug combination (5) · Exercise (4) · Pentoxifylline (4) · Allopurinol (3)
Drugs for Neglected Diseases (34) · Institute of Tropical Medicine, Belgium (16) · U.S. Army Medical Research and Development Command (16) · Hospital Universitário Professor Edgard Santos (10) · Access to Advanced Health Institute (AAHI) (8) · Banaras Hindu University (8) · National Institute of Allergy and Infectious Diseases (NIAID) (8) · University of Brasilia (8) · Bayer (7) · Hospital Sao Rafael (6) · Hospital de Niños R. Gutierrez de Buenos Aires (6) · International Centre for Diarrhoeal Disease Research, Bangladesh (6) · Centro Internacional de Entrenamiento e Investigaciones Médicas (5) · Foundation for Innovative New Diagnostics, Switzerland (5) · Fundacion Nacional de Dermatologia (5)
Brazil (60) · Colombia (28) · United States (28) · Argentina (26) · Bolivia (24) · Ethiopia (22) · India (19) · Democratic Republic of the Congo (12) · Bangladesh (9) · Kenya (9) · France (8) · Sudan (8) · Peru (7) · Spain (7) · Guinea (6)
Shyam Sundar, MD (9) · Jaime Soto, MD (4) · Afif Ben Salah, M.D., Ph.D. (3) · Isabela Ribeiro, MD (3) · Milena Botelho Pereira Soares, PhD (3) · Paulo RL Machado, MD, PhD (3) · Alejandro Llanos-Cuentas, MD, PhD (2) · Antoine Tarral, MD (2) · Antonio L Ribeiro, MD, PhD (2) · Armando O. Schubach, MD, PhD (2) · Bruno SF Souza, MD, Msc (2)
PMID 28379954, PMID 16928995, PMID 23877689, PMID 26881924, PMID 29351667, PMID 30509941, PMID 34053461, PMID 34265407, PMID 7994859, PMID 8937280, PMID 9790423, PMID 10677747, PMID 10707756, PMID 11139981, PMID 11175486, PMID 11353640, PMID 11500748, PMID 12241721, PMID 12456332, PMID 12886425, PMID 12892979, PMID 13849070, PMID 15034825, PMID 15558179, PMID 15837098, PMID 15845889, PMID 16023747, PMID 16202650, PMID 16235350, PMID 16651029, PMID 16702588, PMID 17151373, PMID 17273653, PMID 17339568, PMID 17339569, PMID 17383291, PMID 17582067, PMID 17678433, PMID 17682988, PMID 17689706, PMID 17689724, PMID 17891282, PMID 18053595, PMID 18199497, PMID 18266670, PMID 18545843, PMID 18781879, PMID 19131007, PMID 19131444, PMID 19142374
2016 (3), U19AI065866 (3), 2018 (1), 2019 (1), P50AI098461 (1), R01HL066480 (1), R01NS064905 (1), U01AI129783 (1), Z01HL005264 (1)