70 completed, 29 unknown, 25 recruiting, 11 terminated. 83 Not applicable, 21 Phase 2, 14 Phase 1, 10 Phase 3, 2 Phase 4.
Follow Paraplegia: new trials by email Literature Review of Paraplegia trials Research Report on Paraplegia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord Injury Virtual Reality-Based Hypnotherapy, Conventional Physiotherapy - Spinal Cord Injuries (SCI), Chronic Pain | Not applicable | Not yet recruiting | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | 40 | 2026-10-01 | 2026-09-29 |
| Personal Exoskeleton or Manual Wheelchair: a Comparison of Performance and Satisfaction in Activities of Daily Living Among People With Spinal Cord Injuries, Using the SCED Methodology. Carrying out tasks using the EVE exoskeleton and a manual wheelchair. - Paraplegia, Spinal Cord Injury | Not applicable | Not yet recruiting | Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape | 5 | 2026-10-01 | 2026-09-18 |
| Psilocybin to Treat Depression in Spinal Cord Injury Psilocybin (Usona Institute) - Spinal Cord Injury, Depression - Major Depressive Disorder | Phase 1 / Phase 2 | Recruiting | James J. Peters Veterans Affairs Medical Center | 30 | 2026-08-06 | 2026-08-10 |
| Promoting Neuroplastic Changes of Patients With TBI Motor relearning training with wearable ankle robot, Passive stretching with wearable ankle robot, Gamed-based active movement training with wearable ankle robot - Traumatic Brain Injury | Not applicable | Recruiting | University of Maryland, Baltimore | 100 | 2026-07-16 | 2026-07-17 |
| Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI) Galantamine Hydrobromide Extended Release - Spinal Cord Injury, Traumatic Spinal Cord Injury | Phase 2 / Phase 3 | Recruiting | Northwell Health | 60 | 2026-06-15 | 2026-06-04 |
| Effects of Functional Electrical Stimulation on Spasticity, Quadriceps Muscle Strength and Functional Mobility in Individuals With Paraplegia Conventional Neurorehabilitation, Functional Electrical Stimulation (FES) of Quadriceps Muscle - Spinal Cord Injury, Paraplegia | Not applicable | Not yet recruiting | Istanbul Medipol University Hospital | 40 | 2026-05-10 | 2026-05-19 |
| Comparison Between Palpatory and Ultrasound-guided Methods for Botulinum Toxin Administration in Spastic Paraplegia AbobotulinumtoxinA - Ultrasound-Guided Technique, AbobotulinumtoxinA - Conventional Technique - Spastic Paraplegia | Phase 4 | Recruiting | Universidade Federal Fluminense | 40 | 2026-04-22 | 2026-09-03 |
| Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls. MELPIDA - Hereditary Spastic Paraplegia Type 50 | Phase 3 | Recruiting | Elpida Therapeutics SPC | 24 | 2026-04-01 | 2026-04-20 |
| SCI Epidemiology and Complications Retrospective data analysis - Spinal Cord Injury | Not yet recruiting | Bandırma Onyedi Eylül University | 50 | 2026-03-01 | 2026-02-20 | |
| Self-balancing Personal Exoskeleton for SCI (WIP) Hands-free exoskeleton - Spinal Cord Injuries, Paraplegia and Tetraplegia | Not applicable | Recruiting | Wandercraft | 10 | 2026-02-10 | 2026-04-17 |
| Turkish Validation and Reliability of the John Hopkins In-Room Independence Scale In-room independence assessment - Independence, Hemiplegia | Completed | Sisli Hamidiye Etfal Training and Research Hospital | 100 | 2025-09-01 | 2026-02-27 | |
| Self-balancing Personal Exoskeleton for SCI (WINY) Hands-free exoskeleton - Spinal Cord Injury, Paraplegia and Tetraplegia | Not applicable | Recruiting | Wandercraft | 12 | 2025-08-11 | 2026-02-02 |
| Effects of a Virtual Reality-based Brain-Machine Interface Protocol in Spinal Cord Injury Brain-Machine Interface - Spinal Cord Injury, Able Bodied | Not applicable | Enrolling by invitation | José Gabriel da Silva Figueiredo | 20 | 2025-07-22 | 2026-07-29 |
| Facilitating Neuroplastic Changes of Acute Stroke Survivors Motor relearning training, Passive stretching, Gamed-based active movement training - Stroke | Phase 1 / Phase 2 | Recruiting | University of Maryland, Baltimore | 68 | 2025-06-01 | 2026-07-23 |
| Pilot Study of a Sedentary Behaviour Intervention for Individuals With a Spinal Cord Injury REACH-SCI (Reducing sedEntary Activities to improve Cardiovascular Health in individuals with a Spinal Cord Injury) - Spinal Cord Injury | Not applicable | Active not recruiting | Brunel University | 20 | 2025-05-12 | 2025-09-22 |
| Self-balancing Personal Exoskeleton for SCI (Site 2) Hands-free exoskeleton - Spinal Cord Injuries (SCI), Paraplegia and Tetraplegia | Not applicable | Recruiting | Wandercraft | 24 | 2025-03-31 | 2026-02-02 |
| At-Home Genital Nerve Stimulation for SCI Bowel Genital nerve stimulation - Spinal Cord Injury | Not applicable | Recruiting | MetroHealth Medical Center | 12 | 2025-03-01 | 2026-07-28 |
| Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood Chart review, Semi-structured interview - Spina Bifida, Cerebral Palsy | Completed | Centre Hospitalier Universitaire de Saint Etienne | 128 | 2025-02-14 | 2026-07-16 | |
| Self-balancing Personal Exoskeleton for SCI Hands-free exoskeleton - Spinal Cord Injuries (SCI), Paraplegia and Tetraplegia | Not applicable | Completed | Wandercraft | 27 | 2025-02-12 | 2026-10-15 |
| Upper Limb Function in Paraplegic Individuals: Exploring Endurance, Performance, and Symptoms Paraplegia, Endurance | Completed | Hacettepe University | 32 | 2025-01-15 | 2025-12-26 |
Showing 20 of 148. Sign in to see all of them.
Spinal Cord Injuries (97) · Quadriplegia (58) · Paralysis (13) · Stroke (9) · Motor Activity (7) · Muscle Spasticity (7) · Spastic Paraplegia, Hereditary (6) · Cerebral Palsy (4) · Hemiplegia (4) · Neuralgia (4) · Pressure Ulcer (4) · Brain Injuries, Traumatic (3) · Central Cord Syndrome (3) · Chronic Pain (3)
Pathological Conditions, Signs and Symptoms (148) · Signs and Symptoms (148) · Nervous System Diseases (147) · Neurologic Manifestations (146) · Paralysis (135) · Central Nervous System Diseases (115) · Trauma, Nervous System (102) · Spinal Cord Diseases (101) · Wounds and Injuries (101) · Brain Diseases (19) · Cardiovascular Diseases (13) · Musculoskeletal Diseases (13) · Nutritional and Metabolic Diseases (13) · Neuromuscular Diseases (12) · Peripheral Nervous System Diseases (12)
Exercise (3) · Exoskeleton Device (2) · High-Intensity Interval Training (2) · Muscle Stretching Exercises (2) · Range of Motion, Articular (2) · exoenzyme C3, Clostridium botulinum (2) · 4-Aminopyridine (1) · Acetazolamide (1) · Adrenal Cortex Hormones (1) · Arthroplasty, Replacement, Shoulder (1) · Atorvastatin (1) · Body Composition (1) · Botulinum Toxins, Type A (1) · Brain-Computer Interfaces (1) · Buspirone (1)
Wandercraft (8) · VA Office of Research and Development (7) · ABLE Human Motion S.L. (4) · James J. Peters Veterans Affairs Medical Center (4) · University Hospital, Montpellier (4) · Institut National de la Santé Et de la Recherche Médicale, France (3) · University of Manitoba (3) · University of Miami (3) · Apurano Pharmaceuticals GmbH (2) · Assistance Publique - Hôpitaux de Paris (2) · City University of New York (2) · Elpida Therapeutics SPC (2) · Kessler Foundation (2) · Kristin Zhao, PhD (2) · Mayo Clinic (2)
United States (65) · France (23) · United Kingdom (9) · Germany (7) · Spain (7) · Switzerland (7) · Turkey (Türkiye) (6) · Canada (5) · Israel (5) · Netherlands (4) · Russia (4) · Brazil (3) · Italy (3) · Norway (3) · Denmark (2)
Ann M Spungen, EdD (3) · Maria Knikou, PT, PhD (3) · Allan Levi, MD, PhD (2) · Didier Hannequin, MD, PhD (2) · James Bizon (2) · James Guest, MD, PhD (2) · Jean-Philippe Azulay, MD, PhD (2) · Kim Anderson, PhD (2) · Kristin D. Zhao, Ph.D. (2) · Li-Qun Zhang (2) · Lynn Worobey, PhD/DPT (2) · Patrick Calvas, MD, PhD (2) · Pierre Labauge, MD, PhD (2) · Pierre Pollak, MD, PhD (2)
PMID 28899825, PMID 41491634, PMID 15313841, PMID 15365159, PMID 16193476, PMID 42622482, PMID 12925365, PMID 12925368, PMID 14506070, PMID 14705117, PMID 14736755, PMID 14770181, PMID 15574463, PMID 15596607, PMID 15747371, PMID 15786464, PMID 15895558, PMID 15895562, PMID 15956167, PMID 16055926, PMID 16325416, PMID 16401858, PMID 16434418, PMID 16501573, PMID 16511635, PMID 16518257, PMID 16534102, PMID 16612642, PMID 16682547, PMID 16699786, PMID 17098887, PMID 17130408, PMID 17205300, PMID 17273843, PMID 17321752, PMID 17322883, PMID 17344386, PMID 17503452, PMID 17515546, PMID 17597328, PMID 17605047, PMID 17873417, PMID 17947042, PMID 17957230, PMID 18079167, PMID 18098276, PMID 18332254, PMID 18378516, PMID 18394578, PMID 18602082
2019 (1), 2023 (1), 5IK2RX000881-03 (1), I01RX000528 (1), R01HD084423 (1), R01HD091278 (1), R01NS061304 (1), R01NS115877 (1), R41HD102267 (1), R44AG059275 (1), UL1RR031990 (1)