12 completed, 6 unknown, 1 terminated. 19 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 19 | Completed 12, Unknown 6, Terminated 1 |
| Phase 2 | 3 | Completed 3 |
Follow Pain, Procedural: new trials by email Literature Review of Pain, Procedural trials Research Report on Pain, Procedural
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Fentanyl in Preterm Infants Undergoing Peripherally Inserted Central Catheter Placement Fentanyl, Normal saline - Procedural Pain | Phase 3 | Completed | Mount Sinai Hospital, Canada | 8 | 2024-08-09 | 2025-02-20 |
| The Effect of Local Anesthetic Solution in the Bladder Prior to Botox Injections in the Bladder Alkalinized Lidocaine, Placebo Sodium Chloride 0.9% Inj - Urge Incontinence, Overactive Bladder | Phase 3 | Unknown | Herlev and Gentofte Hospital | 50 | 2022-09-12 | 2022-09-22 |
| Nebulized Lidocaine and Intranasal Midazolam for NGT Insertion in Children Nebulized Lidocaine, Intranasal Midazolam, Placebo - Procedural Anxiety, Procedural Pain | Phase 3 | Unknown | Hamad Medical Corporation | 48 | 2021-08-25 | 2023-03-02 |
| Intranasal Versus Intravenous Drug in Painful Procedure for Outpatient Oncologic Participants intranasal dexmedetomidine, intranasal fentanyl, intravenous ketamine (ketalar®) - Pediatric Cancer, Analgesia | Phase 3 | Unknown | University of Sao Paulo General Hospital | 60 | 2021-06-01 | 2021-04-01 |
| Oral Morphine Versus Ketamine in Pain Management GROUP A, GROUP B - Pain, Procedural | Phase 3 | Completed | Mbarara University of Science and Technology | 44 | 2021-03-01 | 2021-12-20 |
| Saphenous Nerve Block for Partial Meniscectomy Saphenous Nerve Block, Ropivacaine injection - Pain, Joint, Pain, Procedural | Phase 3 | Unknown | Rothman Institute Orthopaedics | 160 | 2021-01-25 | 2021-01-22 |
| The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort Lidocaine - Pain, Procedural | Phase 3 | Completed | Virginia Commonwealth University | 59 | 2020-11-03 | 2024-09-19 |
| VR for Burn Dressing Changes at Home VR-PAT - Burns, Acute Pain | Phase 2 / Phase 3 | Completed | Nationwide Children's Hospital | 36 | 2019-09-05 | 2024-04-30 |
| Needle Procedures Success Rate After Application of Ralydan vs EMLA in Children Lidocaine/Tetracaine patch, Lidocaine/Prilocaine cream - Procedural Pain Relief | Phase 3 | Completed | IRCCS Burlo Garofolo | 339 | 2015-04-01 | 2016-03-28 |
| Vibration and Cold for Pain Relief During Peripheral Intravenous Cannulation in Children With Intellectual Disability Buzzy® device - Pain Relief | Phase 3 | Completed | IRCCS Burlo Garofolo | 71 | 2015-04-01 | 2015-08-06 |
| Tramadol Versus Diclofenac for Reducing Pain Before Outpatient Hysteroscopy Tramadol, Diclofenac, Placebo - Pain, Post Procedural, Pain, Procedural | Phase 3 | Unknown | Cairo University | 210 | 2015-04-01 | 2017-01-23 |
| Safety of Intranasal Fentanyl (PecFent®) in the Treatment of Procedural Pain in the Elderly intranasal fentanyl - Pain Due to Certain Specified Procedures | Phase 2 / Phase 3 | Completed | University Hospital, Grenoble | 58 | 2014-12-08 | 2018-05-08 |
| Sublingual Fentanyl and Procedural Burn Pain Sublingual Fentanyl Spray - Burn Pain | Phase 3 | Terminated | Loyola University | 2 | 2013-09-01 | 2017-07-28 |
| The Effect of Preprocedural Subanesthetic Ketamine on Pain and Anxiety Ketamine, Placebo - Epidural Catheterization, Thoracic | Phase 3 | Completed | Ankara Ataturk Sanatorium Training and Research Hospital | 60 | 2013-06-01 | 2024-03-15 |
| Tablet Distraction for Pain Control During Venipuncture Active distraction using a tablet, Passive distraction - Pain Relief | Phase 3 | Completed | IRCCS Burlo Garofolo | 200 | 2013-03-01 | 2015-11-30 |
| A Test of the Effectiveness of a Device and Distraction for Pediatric Immunization Pain Device: Buzzy, Buzzy: sham device - Procedural Pain | Phase 2 / Phase 3 | Completed | MMJ Labs LLC | 345 | 2010-04-01 | 2011-06-22 |
| Analgesic Effect of Breastmilk for Procedural Pain in Preterm Infants Breastmilk, Oral Sucrose - Procedural Pain | Phase 3 | Unknown | Centre Hospitalier Intercommunal Creteil | 42 | 2009-04-01 | 2009-05-25 |
| Efficacy and Safety of ALGRX 3268 in Children Undergoing Minor Needle-Stick Procedures. ALGRX 3268 - Pain | Phase 3 | Completed | AlgoRx Pharmaceuticals | 504 | 2005-02-01 | 2005-11-16 |
| Efficacy and Safety of ALGRX 3268 in Management of Needlestick Pain in Children. ALGRX 3268 - Procedural Pain | Phase 3 | Completed | AlgoRx Pharmaceuticals | 504 | 2004-12-01 | 2005-09-01 |
Pain (6) · Agnosia (2) · Acute Pain (1) · Anxiety Disorders (1) · Arthralgia (1) · Burns (1) · Hematuria (1) · Intellectual Disability (1) · Neoplasms (1) · Urinary Bladder, Overactive (1) · Urinary Incontinence, Urge (1) · Urinary Tract Infections (1)
Neurologic Manifestations (19) · Pathological Conditions, Signs and Symptoms (19) · Signs and Symptoms (19) · Pain (13) · Nervous System Diseases (3) · Neurobehavioral Manifestations (3) · Mental Disorders (2) · Perceptual Disorders (2) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Hemorrhage (1) · Infections (1) · Joint Diseases (1) · Lower Urinary Tract Symptoms (1) · Male Urogenital Diseases (1)
Ketamine (2) · Lidocaine (2) · Diclofenac (1) · Fentanyl (1) · Midazolam (1) · Ropivacaine (1) · Saline Solution (1) · Sucrose (1) · Tramadol (1)
IRCCS Burlo Garofolo (3) · AlgoRx Pharmaceuticals (2) · Ankara Ataturk Sanatorium Training and Research Hospital (1) · Cairo University (1) · Centre Hospitalier Intercommunal Creteil (1) · Hamad Medical Corporation (1) · Herlev and Gentofte Hospital (1) · Loyola University (1) · MMJ Labs LLC (1) · Mbarara University of Science and Technology (1) · Mount Sinai Hospital, Canada (1) · Nationwide Children's Hospital (1) · Rothman Institute Orthopaedics (1) · University Hospital, Grenoble (1) · University of Sao Paulo General Hospital (1)
United States (6) · Italy (3) · France (2) · Brazil (1) · Canada (1) · Denmark (1) · Egypt (1) · Qatar (1) · Turkey (Türkiye) (1) · Uganda (1)
Egidio Barbi, MD (2) · Giorgio Cozzi, MD (2) · Elena Neri, MD (1) · Eliot Krane, MD (1) · Elizabeth Bortell, DDS (1) · Elodie Zana, MD (1) · Fatihi Toaimah, MD, PhD (1) · Franca Crevatin, RN (1) · Henry Xiang, MD, MPH, PhD (1) · Joseph R Holtman Jr, MD Ph.D. (1) · Niels Klarskov, Prof,MD,DMSc (1) · Silvana Schreiber, RN (1)
PMID 10915627, PMID 11994056, PMID 15278085, PMID 16330518, PMID 16428010, PMID 18299545, PMID 18385262, PMID 18450903, PMID 19482767, PMID 24696691, PMID 26164784, PMID 26401633, PMID 30555754, PMID 31000379, PMID 3195771, PMID 35982492, PMID 39797697, PMID 41007021, PMID 8441570, PMID 9404766
R44HD056647 (1)