44 completed, 18 unknown, 12 recruiting, 6 active not recruiting. 38 Not applicable, 14 Phase 2, 8 Phase 1, 5 Phase 3, 4 Phase 4.
Follow Orthostatic Hypotension: new trials by email Literature Review of Orthostatic Hypotension trials Research Report on Orthostatic Hypotension
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Transcutaneous Spinal Stimulation on Blood Pressure and Orthostasis in Spinal Cord Injury Tilt test with stimulation (real-time effects): Intervention 1, 20 sessions of stimulation (Intervention 2) - Spinal Cord Injuries, Hypotension | Not applicable | Not yet recruiting | Kessler Foundation | 10 | 2026-09-01 | 2026-06-29 |
| Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE) Wearable holter monitor - Orthostatic Hypotension, Reflex Syncope | Recruiting | Boston Scientific Corporation | 40 | 2026-08-06 | 2026-10-14 | |
| State of Knowledge Among Nurses Regarding the Screening for Orthostatic Hypotension in Elderly Individuals in Acute Geriatric Medicine and Medical and Rehabilitation Services Administration of questionnaires on nurses' knowledge of orthostatic hypotension, its measurement, diagnosis and management - Orthostatic Hypotension | Not yet recruiting | Hôpital NOVO | 30 | 2026-07-01 | 2026-07-31 | |
| Orthostatic And Postprandial Hypotension In Hospitalized Older Adults (HOPE65) Orthostatic Hypotension, Postprandial Hypotension | Not yet recruiting | University Medical Centre Ljubljana | 500 | 2026-04-01 | 2026-03-20 | |
| Research, Development, and Application of Intelligent Diagnostic System for Orthostatic Hypotension Intelligent diagnostic system for orthostatic hypotension - Orthostatic Hypotension | Not yet recruiting | Xuanwu Hospital, Beijing | 2000 | 2026-03-01 | 2026-01-07 | |
| Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive Individuals Hypertension, Autonomic Dysfunction | Recruiting | University Medical Centre Ljubljana | 120 | 2025-10-15 | 2026-03-19 | |
| Deciphering the Mechanisms of Central BP Regulation in Patients With PD Associated With Orthostatic Hypotension Lower body negative pressure - Parkinson Disease, Orthostatic Hypotension | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 130 | 2025-10-01 | 2025-08-24 | |
| Effects of Breathing Retraining Exercises in Pregnant Females With Postural Orthostatic Tachycardia Syndrome. diaphragmatic breathing exercise, educational retraining - Orthostatic Hypotension, Heart Rate | Not applicable | Recruiting | Riphah International University | 44 | 2025-08-31 | 2026-05-11 |
| Evaluation of the Contribution of Lower Limb and/or Abdominal Compression on Orthostatic Hypotension the supine/standing postural change test - Orthostatic Hypotension | Not applicable | Completed | Gérond'if | 43 | 2025-02-14 | 2026-04-03 |
| The Value of Near-infrared Spectroscopy and Blood Pressure Measurements in Estimating Future Fall Risk in Older Adults Falls, Orthostatic Hypotension | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 141 | 2024-12-04 | 2024-12-19 | |
| POLish Registry of CArdioneuroablation and CArdioneuromodulation cardioneuroablation, SN sparing hybrid ablation, Cardiac sympathetic denervation - Vasovagal Syndrome VVS, Cardioinhibitory Carotid Sinus Syndrome CSS | Recruiting | SABAMED Medical Center Ltd. | 1000 | 2024-11-21 | 2025-09-29 | |
| SalT Supplementation in Older Adults With Orthostatic Intolerance Disorders Salt supplementation (encapsulated sodium chloride) - Orthostatic Hypotension | Phase 2 | Active not recruiting | University of Galway | 42 | 2024-07-09 | 2026-06-22 |
| Frequency of Orthostatic Hypotension in Patients Who Underwent Colonoscopy Orthostatic Hypotension | Unknown | Ankara University | 150 | 2024-05-01 | 2025-01-29 | |
| The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's Patients Comprehensive rehabilitation training, Rise-bed Training - Orthostatic Hypotension | Not applicable | Unknown | Copka Sonpashan | 80 | 2024-04-01 | 2024-03-25 |
| Assessment of the Mechanism of Non-cardiac Syncope ABPM plys SCAFB - Syncope, Syncope, Vasovagal | Completed | Istituto Auxologico Italiano | 330 | 2024-04-01 | 2024-07-17 | |
| The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's Patients Comprehensive rehabilitation training, Rise-bed Training - Orthostatic Hypotension | Not applicable | Unknown | Zeng Changhao | 80 | 2024-02-29 | 2024-03-06 |
| Efficacy, Safety and Response Predictors of Adjuvant Astragalus for Cognition in Orthostatic Hypotension Routine treatment, add-on low dose Astragalus, add-on high dose Astragalus - Orthostatic Hypotension, Alzheimer Disease | Phase 2 | Unknown | Fujian Medical University Union Hospital | 66 | 2024-02-20 | 2024-01-05 |
| A Novel Device for the Treatment of Postural Hypotension - a Signal of Effectiveness Study. ISO-101 - Orthostatic Hypotension | Not applicable | Unknown | Isotech Ltd | 30 | 2023-12-15 | 2024-02-22 |
| Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI) Orthostatic challenge, Biostim-5 transcutaneous spinal stimulation - Mapping, Biostim-5 transcutaneous spinal stimulation - "Optimal" testing - Spinal Cord Injuries, Spinal Cord Diseases | Not applicable | Recruiting | Kessler Foundation | 12 | 2023-12-01 | 2025-09-02 |
| Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury TESCoN or SCONE device - Thoracic stimulation, TESCoN or SCONE device - Lumbosacral stimulation - Spinal Cord Injury, Autonomic Dysfunction | Not applicable | Recruiting | University of British Columbia | 30 | 2023-10-03 | 2025-12-08 |
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Hypotension, Orthostatic (94) · Spinal Cord Injuries (16) · Parkinson Disease (11) · Orthostatic Intolerance (10) · Hypotension (7) · Multiple System Atrophy (7) · Pure Autonomic Failure (7) · Primary Dysautonomias (6) · Syncope (6) · Syncope, Vasovagal (6) · Autonomic Nervous System Diseases (5) · Dizziness (5) · Autonomic Dysreflexia (3) · Cardiovascular Diseases (3) · Central Nervous System Diseases (3)
Vascular Diseases (93) · Cardiovascular Diseases (91) · Nervous System Diseases (91) · Autonomic Nervous System Diseases (89) · Primary Dysautonomias (88) · Hypotension (87) · Orthostatic Intolerance (84) · Pathological Conditions, Signs and Symptoms (31) · Central Nervous System Diseases (29) · Signs and Symptoms (26) · Neurologic Manifestations (22) · Brain Diseases (17) · Neurodegenerative Diseases (17) · Wounds and Injuries (17) · Basal Ganglia Diseases (15)
Midodrine (11) · Droxidopa (8) · Pyridostigmine Bromide (3) · Physical Therapy Modalities (2) · Standing Position (2) · Tilt-Table Test (2) · 3,4-dihydroxyphenylserine aldolase (1) · Acarbose (1) · Acetazolamide (1) · Adrenal Cortex Hormones (1) · Analgesics, Opioid (1) · Antihypertensive Agents (1) · Aquatic Therapy (1) · Atomoxetine Hydrochloride (1) · Blood Pressure Determination (1)
Vanderbilt University Medical Center (5) · James J. Peters Veterans Affairs Medical Center (4) · University of British Columbia (4) · Hvidovre University Hospital (3) · Kessler Foundation (3) · Mayo Clinic (3) · Vanderbilt University (3) · Boston Scientific Corporation (2) · Chelsea Therapeutics (2) · Copenhagen University Hospital, Hvidovre (2) · Istituto Auxologico Italiano (2) · Medical Research Foundation, The Netherlands (2) · Satish R. Raj (2) · University Medical Centre Ljubljana (2) · University of Texas at Austin (2)
United States (45) · Canada (7) · Netherlands (6) · Denmark (5) · France (5) · Israel (3) · Poland (3) · China (2) · Italy (2) · Slovenia (2) · Spain (2) · Switzerland (2) · Taiwan (2) · Turkey (Türkiye) (2) · United Kingdom (2)
Italo Biaggioni, MD (5) · Jill Wecht, EdD (3) · Satish R Raj, MD MSCI (3) · Gail F Forrest, PhD (2) · Luis E Okamoto, MD (2) · Amnon Mosek, MD (1) · Ana-Marija Hristovska, MD (1) · Andrei Krassioukov, MD, PhD, FRCPC (1) · Andrew Smyth (1) · Athanase Benetos, Pr (1) · Aurelio Tobon, MD (1) · Catriona Reddin (1) · Charles W Lapp, M.D. (1) · David Robertson, MD (1)
PMID 21762873, PMID 10662747, PMID 11904109, PMID 11927799, PMID 12119802, PMID 12832331, PMID 12885750, PMID 15066944, PMID 15666063, PMID 15710782, PMID 15738343, PMID 17384373, PMID 17515447, PMID 17515448, PMID 18850311, PMID 20801263, PMID 20837887, PMID 21420883, PMID 22311903, PMID 23774314, PMID 23845791, PMID 24326693, PMID 26026216, PMID 26492477, PMID 26953217, PMID 27271310, PMID 27372462, PMID 27538531, PMID 27778639, PMID 28327122, PMID 28494751, PMID 29223724, PMID 30003579, PMID 31107279, PMID 31334462, PMID 32145658, PMID 32307533, PMID 33462120, PMID 33782836, PMID 33934709, PMID 34000076, PMID 34657222, PMID 35366432, PMID 35441700, PMID 35526605, PMID 36602886, PMID 38262617, PMID 38561817, PMID 38588457, PMID 38712567
R01HL144568 (2), K23HD102663 (1), P01HL056693 (1), P01NS044233 (1), R01AG059613 (1), U54NS065736 (1)