124 completed, 37 recruiting, 30 unknown, 13 not yet recruiting. 176 Not applicable, 7 Phase 2, 3 Phase 3, 3 Phase 4, 1 Early Phase 1.
Follow Older Adults: new trials by email Literature Review of Older Adults trials Research Report on Older Adults
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Wearable Sensor for Early Detection and Monitoring of Cognitive Decline Mild Cognitive Impairment (MCI), Older Adults With Cognitive Decline | Not yet recruiting | BioSensics | 100 | 2026-12-15 | 2026-09-02 | |
| HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide Calcium-HMB Plus Vitamin D3, Matching placebo - Type 2 Diabetes Mellitus (T2DM), Sarcopenia | Phase 2 | Not yet recruiting | Vanderbilt University Medical Center | 90 | 2026-12-01 | 2026-08-28 |
| AI-Adaptive AR Training for Balance and Falls Prevention in Older Adults AI-Enhanced Augmented Reality Balance and Mobility Training - Older Adults, Older Adults, Balance | Not applicable | Not yet recruiting | McMaster University | 30 | 2026-11-30 | 2026-08-25 |
| Technology Use, Safe Health Information, and Artificial Intelligence Among Older Adults E-Health Literacy Based Education - Older Adults, Nursing Homes | Not applicable | Not yet recruiting | Ondokuz Mayıs University | 46 | 2026-11-01 | 2026-10-19 |
| Frailty, Geriatric Syndromes and Care Pathways of Older Adults Living With HIV in West Africa Older Adults | Recruiting | ANRS, Emerging Infectious Diseases | 600 | 2026-09-28 | 2026-10-02 | |
| Evaluation of Choose to Move Replacement Ready (CTM-RR) Choose to Move Replacement Ready - Osteoarthritis (OA), Osteoarthritis (OA) of the Hip | Not applicable | Recruiting | University of British Columbia | 210 | 2026-09-01 | 2026-08-24 |
| Feasibility and Effects of Inspiratory Muscle Training Combined With Blood Flow Restriction for Frail Older Adults Exercise, Sham Control - Frailty Syndrome, Older Adults | Not applicable | Recruiting | Taipei Medical University | 30 | 2026-08-19 | 2026-10-05 |
| Perioperative Transcranial Photobiomodulation and Delayed Neurocognitive Recovery in Older Patients Transcranial photobiomodulation therapy, Transcranial pseudo-photobiomodulation - Older Adults, Surgery | Not applicable | Recruiting | Peking University First Hospital | 130 | 2026-08-05 | 2026-08-10 |
| N-of-1 Trial to Promote Beta-Blocker Titration in Heart Failure N-of-1 trials, Enhanced usual care - Heart Failure, Beta-blocker | Not applicable | Enrolling by invitation | Brigham and Women's Hospital | 50 | 2026-07-31 | 2026-09-21 |
| Impact of Respiratory Muscle Training on Cognition in Older Adults Inspiratory Muscle Training - Older Adults | Not applicable | Enrolling by invitation | Acibadem University | 24 | 2026-07-24 | 2026-07-28 |
| An AI-Based Prediction of Cognitive Capacity in Older Adults and Individuals With Mild Cognitive Impairment During Virtual Reality Driving Tasks Mild Cognitive Impairment (MCI), Virtual Reality | Not yet recruiting | National Cheng-Kung University Hospital | 192 | 2026-06-20 | 2026-06-18 | |
| Evaluating Health Outcomes of AI-Based Fitness Wearables and App Programs in Older Adults Living Alone With Cognitive Decline Fitness app for self-efficacy, Social network via app for social support, Health education app targeting outcome expectations - Older Adults With Cognitive Decline, Older Adults | Not applicable | Recruiting | The University of Tennessee, Knoxville | 64 | 2026-06-08 | 2026-06-15 |
| Intranasal Dexmedetomidine-esketamine on Sleep and Cognition in Older Adults With Mild-to-moderate Cognitive Impairment Dexmedetomidine-esketamine combination, Placebo - Older Adults, Cognitive Impairment | Phase 4 | Not yet recruiting | Peking University First Hospital | 60 | 2026-06-01 | 2026-06-01 |
| Vaccination Response Modulation With a Targeted Rapamycin Protocol Study Sirolimus (RAPAMUNE), Influenza vaccine (Sequiris Fluad Quad), RSV vaccine (Pfizer Abrysvo) - Vaccine Immune Response, Haemodialysis Patients | Phase 2 | Not yet recruiting | Central Adelaide Local Health Network Incorporated | 60 | 2026-05-01 | 2026-05-14 |
| The Targeted Neurocognitive Training (TNT) Study Targeted Neurocognitive Training - HIV, Aging | Not applicable | Withdrawn | University of Alabama at Birmingham | 2026-05-01 | 2026-05-29 | |
| Orthopedic Procedures and Postoperative Delirium in Older Adults in the Czech Republic Frailty, Cognitive Impairment | Recruiting | Tomas Bata Hospital, Czech Republic | 400 | 2026-04-24 | 2026-07-09 | |
| Person-Centered Occupational Therapy in Older Adults Person-Centered Occupational Therapy Approach Delivered via Telerehabilitation - Older Adults, Telerehabilitation | Not applicable | Completed | Atlas University | 160 | 2026-04-15 | 2026-08-05 |
| The Count Me In Program in Support of Social Participation for Older People With Loss of Autonomy The Count Me In Program - Older Adults, Loss of Autonomy | Not applicable | Not yet recruiting | Université du Québec à Trois-Rivières | 8 | 2026-04-01 | 2026-02-27 |
| Dyadic Management Intervention in Older People With Co-occurring Cognitive Impairment and Diabetes as a Supplementary Approach to Chronic Diseases Self-Management Program CDSMP + caregiver support, Usual Care - Choroid Disease, Caregiver | Not applicable | Recruiting | The Hong Kong Polytechnic University | 309 | 2026-04-01 | 2026-09-17 |
| A Multi-Level Strategy for De-implementing Mammography Overuse Among Older Women Enhanced Usual Care (EUC), Multilevel De-Implementation Strategy - Mammography, Medical Overuse | Not applicable | Recruiting | Columbia University | 500 | 2026-03-11 | 2026-09-25 |
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