76 active not recruiting. 76 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 76 | Active not recruiting 76 |
Follow Nervous System Diseases: new trials by email Literature Review of Nervous System Diseases trials Research Report on Nervous System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical and Economic Evaluation of Point-of-care Ultrasound-guided Infiltration for Subacromial and Carpal Tunnel Syndromes in Primary Care: a Cluster-randomized Study Protocol. Standard Oral Treatment, Conventional Infiltration, Ultrasound-Guided Infiltration - Subacromial Impingement Syndrome, Carpal Tunnel Syndrome (CTS) | Phase 4 | Active not recruiting | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 225 | 2026-06-01 | 2026-07-09 |
| The Improvement of Low-dose Esketamine on Postoperative Depression in Patients Undergoing Bariatric Surgery With Preoperative Depression Esketamine, Dexmedetomidine - Depressed, Bariatric Surgery | Phase 4 | Active not recruiting | The First Hospital of Jilin University | 40 | 2026-05-01 | 2026-05-08 |
| Recombinant Herpes Zoster Vaccine for Prevention of Cardiovascular Events and Dementia Recombinant Herpes Zoster Vaccine (Shingrix) - Cardiovascular Disease, Dementia | Phase 4 | Active not recruiting | Tor Biering-Sørensen | 168460 | 2026-04-28 | 2026-10-14 |
| EFficacy and safEty of cRisugabalin on nocipLastic paIn in Patients With Parkinson's Disease (RELIEF-PD): a Multicentre, Double-blind, Randomised Controlled Trial Crisugabalin, Placebo - PARKINSON DISEASE (Disorder) | Phase 4 | Active not recruiting | Guangdong Provincial People's Hospital | 166 | 2026-03-13 | 2026-09-14 |
| Nerivio Efficacy Under High-Frequency Use Nerivio (REN device) - Migraine | Phase 4 | Active not recruiting | Theranica | 2000 | 2026-01-08 | 2026-01-13 |
| A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Chinese Participants With SOD-1 Amyotrophic Lateral Sclerosis (ALS) Tofersen - Amyotrophic Lateral Sclerosis | Phase 4 | Active not recruiting | Biogen | 12 | 2025-12-11 | 2026-08-13 |
| Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy Ondansetron Intraperitoneal Lavage, Saline Intraperitoneal Lavage - Postoperative Pain Management, Laparoscopic Cholecystectomy | Phase 4 | Active not recruiting | Instituto Mexicano del Seguro Social | 40 | 2025-12-01 | 2025-12-16 |
| Phase 4 Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Chinese Participants With Generalized Myasthenia Gravis Rozanolixizumab - Myasthenia Gravis | Phase 4 | Active not recruiting | UCB Biopharma SRL | 40 | 2025-12-01 | 2026-10-29 |
| A Study Testing How Well the Drug Extract of Ginkgo Biloba Leaves Tablets Works for People With Memory or Thinking Problems After a Stroke When Added to Standard Treatment Extract of Ginkgo Biloba Leaves Tablets 240 mg (2 x 40 mg, t.i.d.), Standard of care (SoC) Group - Ischemic Stroke Hospitalized, Impairment, Cognitive | Phase 4 | Active not recruiting | Dr. Willmar Schwabe GmbH & Co. KG | 400 | 2025-11-28 | 2026-10-30 |
| Evaluation of MIG-SPRAY Treatment on Migraine MIG-SPRAY - Migraine | Phase 4 | Active not recruiting | University Hospital, Clermont-Ferrand | 45 | 2025-09-15 | 2026-03-18 |
| GLP-1s to Enhance Lasting Optimal Weight Tirzepatide - Obesity | Phase 4 | Active not recruiting | Wake Forest University Health Sciences | 40 | 2025-07-07 | 2026-10-02 |
| A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Participants With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis Ocrelizumab - Relapsing Multiple Sclerosis, Primary Progressive Multiple Sclerosis | Phase 4 | Active not recruiting | Hoffmann-La Roche | 60 | 2025-07-04 | 2026-09-30 |
| Combination of Remimazolam and Propofol During Drug-induced Sleep Endoscopy Remimazolam and Propofol, Propofol, Midazolam and propofol - Sedative Effect During Drug-induced Sleep Endoscopy, Obstructive Sleep Apnea (OSA) | Phase 4 | Active not recruiting | Dan Liu | 174 | 2025-03-01 | 2026-02-24 |
| Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Children With Phenylketonuria L-carnitine - Phenylketonuria | Phase 4 | Active not recruiting | Mansoura University | 176 | 2025-02-01 | 2025-04-04 |
| Clinical Trial on 7-day Followed by Maintenance Therapy for 10 Weeks vs. 14-day and no Maintenance Course of Prednisolone for the Treatment of Infantile Epileptic Spasms Syndrome (IESS) Short-Duration Oral Prednisolone with Extended Tapering, Standard Oral Prednisolone Regimen with Tapering - Spasms, Infantile, Prednisolone | Phase 4 | Active not recruiting | University of Colombo | 182 | 2025-01-01 | 2025-02-24 |
| Factors Determining the Efficacy of Botulinum Toxin for Arm Tremor in Dystonia Polymyography, Muscle ultrasound, (Functional) magnetic resonance imaging - Dystonic Tremor Syndrome | Phase 4 | Active not recruiting | Radboud University Medical Center | 60 | 2025-01-01 | 2026-08-14 |
| Nebulized Dexmedetomidine for Post-Anesthesia Delirium in Preschool Children Nebulized Dexmedetomidine for Post-Anesthesia Delirium in Preschool Children, Nebulized 0.9% Normal Saline - Emergence Delirium, Delirium - Postoperative | Phase 4 | Active not recruiting | Udayana University | 72 | 2024-12-13 | 2025-01-22 |
| Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis Ofatunumab - Multiple Sclerosis | Phase 4 | Active not recruiting | Novartis Pharmaceuticals | 24 | 2024-11-25 | 2026-08-12 |
| Monitoring JE Antibody Levels in Healthy Populations and Immunization Strategy in Low-Prevalence Areas Liaoning Chengda Inactivated Japanese Encephalitis Vaccine - Japanese Encephalitis | Phase 4 | Active not recruiting | Liaoning Chengda Biotechnology CO., LTD | 250 | 2024-11-14 | 2024-12-13 |
| A Study on Safety and Effectiveness of Long-term Treatment With Vamorolone in Boys With Duchenne Muscular Dystrophy vamorolone 40 mg/mL oral suspension - Duchenne Muscular Dystrophy | Phase 4 | Active not recruiting | Santhera Pharmaceuticals | 80 | 2024-11-10 | 2026-04-23 |
Showing 20 of 76. Sign in to see all of them.
Agnosia (6) · Multiple Sclerosis (6) · Cognitive Dysfunction (5) · Stroke (5) · Alzheimer Disease (4) · Cardiovascular Diseases (4) · Multiple Sclerosis, Relapsing-Remitting (4) · Carpal Tunnel Syndrome (3) · Dementia (3) · Ischemic Stroke (3) · Migraine Disorders (3) · Myocardial Infarction (3) · Recurrence (3) · Depression (2) · Glycogen Storage Disease Type II (2)
Central Nervous System Diseases (36) · Pathological Conditions, Signs and Symptoms (33) · Brain Diseases (31) · Neurologic Manifestations (22) · Signs and Symptoms (22) · Pathologic Processes (20) · Immune System Diseases (15) · Mental Disorders (15) · Autoimmune Diseases (14) · Neuromuscular Diseases (14) · Neurocognitive Disorders (13) · Autoimmune Diseases of the Nervous System (12) · Demyelinating Diseases (12) · Vascular Diseases (12)
ocrelizumab (5) · Saline Solution (3) · Atorvastatin (2) · Cladribine (2) · Dexmedetomidine (2) · Fingolimod Hydrochloride (2) · Ibuprofen (2) · ofatumumab (2) · 1-((2-hydroxyethyl)amino)-2-amino-1,2-dideoxyglucose triphenyltin(IV) (1) · Abiraterone Acetate (1) · Acetaminophen (1) · Alemtuzumab (1) · Aspirin (1) · Botulinum Toxins (1) · Cannabidiol (1)
Novartis Pharmaceuticals (4) · Amgen (2) · Green Valley (Shanghai) Pharmaceuticals Co., Ltd. (2) · Hoffmann-La Roche (2) · Monash University (2) · Abant Izzet Baysal University (1) · Amsterdam UMC, location VUmc (1) · Biogen (1) · CanSino Biologics Inc. (1) · Centre Hospitalier Universitaire de Nice (1) · Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec (1) · Cerus Endovascular, Inc. (1) · Chinese University of Hong Kong (1) · Dan Liu (1) · Diakonhjemmet Hospital (1)
United States (25) · China (16) · Netherlands (7) · Canada (6) · Brazil (5) · Spain (5) · United Kingdom (5) · France (4) · Australia (3) · Czechia (3) · Germany (3) · Israel (3) · Italy (3) · Poland (3) · South Korea (3)
Sophia Zoungas, MBBS, FRACP (2) · Alex Martino Cinnera, PhD (1) · Alit Stark-Inbar, PhD (1) · Amit Bar-Or, M.D. (1) · Anke Snijders, PhD (1) · Bernhard Zapletal, M.D. (1) · Carukshi Arambepola, MSc, MD (1) · Daniel Ontaneda, MD, MSc (1) · David VanderWeele, M.D., M.P.H. (1) · Demetrius Lopes, MD (1)
PMID 10227938, PMID 10433490, PMID 10718794, PMID 11028830, PMID 11266262, PMID 11474424, PMID 11772809, PMID 11826129, PMID 14570668, PMID 15189396, PMID 1531705, PMID 1535245, PMID 16000093, PMID 16464423, PMID 16717343, PMID 17054284, PMID 19256134, PMID 19707145, PMID 20053272, PMID 20423760, PMID 20665856, PMID 20723861, PMID 21079721, PMID 21944510, PMID 22288883, PMID 23630439, PMID 24682348, PMID 25060026, PMID 25102706, PMID 2526302, PMID 25604089, PMID 25665674, PMID 25768238, PMID 25777666, PMID 26905574, PMID 26993976, PMID 27380615, PMID 27765196, PMID 27931603, PMID 28008467, PMID 28065447, PMID 28145040, PMID 28231907, PMID 28237044, PMID 28495432, PMID 29078868, PMID 29146668, PMID 29183961, PMID 29340809, PMID 29622159
2023 (3), 2008 (1), 2018 (1), 2019 (1), 2025 (1), U01AI195194 (1)