51 completed, 5 unknown, 3 not yet recruiting, 2 recruiting. 63 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 63 | Completed 51, Unknown 5, Not yet recruiting 3, Recruiting 2, Terminated 1, Withdrawn 1 |
Follow Myelitis: new trials by email Literature Review of Myelitis trials Research Report on Myelitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase IV Clinical Study of Sequential Vaccination of Sabin Strain and Wild Strain Inactivated Poliovirus Vaccine 2wIPV+1sIPV, 1wIPV+2sIPV, 3wIPV - Poliomyelitis | Phase 4 | Recruiting | Sinovac Biotech Co., Ltd | 480 | 2025-11-27 | 2026-03-09 |
| Phase IV Clinical Study of sIPV Administration in Adolescent and Adult Populations sIPV, DTaP-IPV-Hib - Poliomyelitis | Phase 4 | Recruiting | Sinovac Biotech Co., Ltd | 180 | 2025-09-26 | 2026-01-21 |
| Study of Concomitant Administration of the sIPV and DTaP or MMR sIPV, DTaP, bOPV 1,3 - Polio, Diphteria, Tetanus and Pertussis | Phase 4 | Not yet recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 2640 | 2025-05-15 | 2025-04-17 |
| Immunogenicity of Different Primary Immunization Schedules with Inactivated Poliovirus Vaccine (IPV) Plus Pentavalent Vaccine (DTwP-HBV-Hib) or with Hexavalent Vaccine (DTwP-HBV-Hib-IPV) Pentavalent vaccine, Hexavalent vaccine, Inactivated poliovirus vaccine (IPV) - Polio | Phase 4 | Not yet recruiting | International Centre for Diarrhoeal Disease Research, Bangladesh | 1190 | 2025-01-28 | 2024-12-27 |
| Booster Dose of sIPV Co-administered With MMR and HepA-I. sIPV, MMR, HepA-I - Poliomyelitis | Phase 4 | Completed | Sinovac Biotech Co., Ltd | 889 | 2024-08-08 | 2026-01-16 |
| Phase IV Study of Concomitant Administration of the sIPV and HepA sIPV (booster dose at 18 months of age), HepA-L, HepA-I - Polio, Hepatitis A | Phase 4 | Not yet recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 2000 | 2024-06-15 | 2024-06-14 |
| Sequential Vaccination of Poliomyelitis Vaccine (Vero Cells), Inactivated, Sabin Strains From Different Manufacturers sIPV - Poliomyelitis | Phase 4 | Completed | Sinovac Biotech Co., Ltd | 200 | 2024-05-20 | 2025-03-14 |
| A Study to Evaluate Pharyngeal Immunity to Poliovirus Type-2 nOPV2 - Poliomyelitis | Phase 4 | Completed | Fidec Corporation | 501 | 2023-11-09 | 2026-09-03 |
| Immunogenicity of Novel Oral Poliovirus Vaccine Type 2 (nOPV2), bOPV and IPV polio vaccines: nOPV2, bOPV, IPV - Polio | Phase 4 | Unknown | International Centre for Diarrhoeal Disease Research, Bangladesh | 880 | 2023-11-01 | 2023-11-07 |
| Assessing Immunogenicity of Intramuscular Sabin Inactivated Poliovirus Vaccine and Non-inferiority of Intradermal Fractional Inactivated Poliovirus Vaccine Full dose Sabin Inactivated Poliovirus Vaccine produced by IMBCAMS, Fractional (1/5) Dose Sabin Inactivated Poliovirus Vaccine produced by IMBCAMS, Full dose Sabin Inactivated Poliovirus Vaccine produced by BIBP - Poliomyelitis | Phase 4 | Completed | Centers for Disease Control and Prevention | 1224 | 2022-07-26 | 2025-03-19 |
| A Safety Study of Sabin Inactivated Poliovirus Vaccine in Infants sIPV vaccine /DTaP vaccine, sIPV vaccine /Hepatitis A inactivated vaccine /MMR vaccine - Poliomyelitis | Phase 4 | Completed | Sinovac Biotech Co., Ltd | 3200 | 2022-06-13 | 2023-01-12 |
| Evaluation of Persistence of Immunity in 4-year-old Children Previously Immunised With IPV-Al AJV (Picovax®) IPV-Al - Poliomyelitis | Phase 4 | Completed | AJ Vaccines A/S | 163 | 2020-11-20 | 2021-06-22 |
| Immunogenicity and Safety of the Booster Dose of Polio Vaccine With Different Primary Sequential Schedules in China vaccinated with Sabin IPV, vaccinated with bOPV - Polio, Vaccine Reaction | Phase 4 | Completed | Zhejiang Provincial Center for Disease Control and Prevention | 387 | 2020-11-05 | 2022-03-07 |
| Immunogenicity of Intramuscular and Intradermal IPV fIPV (0.1 mL) ID, fIPV (0.1mL) IM, fIPV (0.2mL) IM - Poliomyelitis | Phase 4 | Terminated | Centers for Disease Control and Prevention | 958 | 2019-10-06 | 2022-05-18 |
| Monovalent Oral Poliovirus Vaccine Type 1 Intestinal and Humoral Immunity Study mOPV1, bOPV, fIPV - Poliomyelitis | Phase 4 | Completed | Centers for Disease Control and Prevention | 1256 | 2018-12-18 | 2021-02-21 |
| Persistence of IPV Immunity Inactivated Polio Vaccine (IPV) - Poliomyelitis | Phase 4 | Completed | Tribhuvan University Teaching Hospital, Institute Of Medicine. | 502 | 2018-11-21 | 2020-04-07 |
| Assessment of Poliovirus Type 2 Immunogenicity of One and Two Dose Schedule With IPV and fIPV When Administered at 9-13 Months of Age in Bangladesh IPV - Poliomyelitis | Phase 4 | Unknown | International Centre for Diarrhoeal Disease Research, Bangladesh | 300 | 2018-09-27 | 2022-04-13 |
| A Study of Immunogenicity and Seroconversion With Sabin IPV Schedules in China. Sabin IPV - Poliomyelitis | Phase 4 | Completed | Centers for Disease Control and Prevention, China | 560 | 2018-05-28 | 2020-06-24 |
| Sero-conversion Study for a Two-dose Schedule of Sabin IPV in China Sabin IPV - Poliomyelitis | Phase 4 | Completed | Centers for Disease Control and Prevention, China | 280 | 2018-05-24 | 2020-06-24 |
| Consistency Study for Three Commercial Lots of Inactivated Poliomyelitis Vaccine Made From Sabin Strain sIPV batch 1, sIPV batch 2, sIPV batch 3 - Poliomyelitis | Phase 4 | Completed | Institute of Medical Biology, Chinese Academy of Medical Sciences | 1200 | 2018-04-15 | 2023-10-11 |
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Poliomyelitis (59) · Tetanus (20) · Diphtheria (19) · Whooping Cough (12) · Haemophilus Infections (8) · Hepatitis B (5) · Multiple Sclerosis (2) · Myelitis, Transverse (2) · Optic Neuritis (2) · Autoimmune Diseases of the Nervous System (1) · Cerebellar Diseases (1) · Demyelinating Autoimmune Diseases, CNS (1) · Demyelinating Diseases (1) · HIV Seropositivity (1) · HTLV-I Infections (1)
Central Nervous System Diseases (63) · Central Nervous System Infections (63) · Nervous System Diseases (63) · Neuroinflammatory Diseases (63) · Spinal Cord Diseases (63) · Infections (62) · Neuromuscular Diseases (60) · RNA Virus Infections (60) · Virus Diseases (60) · Enterovirus Infections (59) · Picornaviridae Infections (59) · Bacterial Infections (20) · Bacterial Infections and Mycoses (20) · Clostridium Infections (20)
Poliovirus Vaccine, Inactivated (7) · Tetanus Toxoid (5) · Aging (4) · Pentavac (3) · RIX4414 vaccine (3) · Diphtheria-Tetanus-acellular Pertussis Vaccines (2) · Interferon beta-1a (2) · Measles-Mumps-Rubella Vaccine (2) · Poliovirus Vaccine, Oral (2) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (2) · Blood Specimen Collection (1) · Hexavac (1) · HibTITER protein, Haemophilus influenzae (1) · Methotrexate (1) · Methylprednisolone (1)
GlaxoSmithKline (10) · Sanofi Pasteur, a Sanofi Company (8) · Centers for Disease Control and Prevention (7) · Sinovac Biotech Co., Ltd (5) · Aga Khan University (4) · Fidec Corporation (4) · Institute of Medical Biology, Chinese Academy of Medical Sciences (4) · Sanofi (4) · International Centre for Diarrhoeal Disease Research, Bangladesh (3) · Centers for Disease Control and Prevention, China (2) · Zhejiang Provincial Center for Disease Control and Prevention (2) · AJ Vaccines A/S (1) · Beth Israel Deaconess Medical Center (1) · London School of Hygiene and Tropical Medicine (1) · MP Biomedicals, LLC (1)
China (16) · Bangladesh (9) · United States (5) · Canada (4) · Pakistan (4) · Finland (3) · Germany (3) · Italy (3) · Australia (2) · Czechia (2) · France (2) · Norway (2) · Panama (2) · Philippines (2) · Russia (2)
Ali F Saleem, MBBS, MCR, FCPS (1) · Ali F Saleem, MBBS,FCPS,MSc (1) · Ali Saleem (1) · Anita K.M Zaidi, MBBS, SM (1) · Bianca Weinstock-Guttman, M.D. (1) · Concepcion Estivariz, MD (1) · Dr. K Zaman, PhD (1) · Ed Clarke, MD (1) · Edwin J Asturias, MD (1) · Farheen Quadri, MBBS, MSCR (1) · Gagandeep Kang, MD, PhD (1) · Harish Verma, DCH (1)
PMID 33487470, PMID 16831964, PMID 20448468, PMID 20616762, PMID 23077849, PMID 25882172, PMID 26318714, PMID 26407255, PMID 27212429, PMID 27364568, PMID 28444156, PMID 28455172, PMID 28495264, PMID 29477307, PMID 29571817, PMID 30376086, PMID 31104832, PMID 31776027, PMID 32442523, PMID 32621741, PMID 32798224, PMID 33612341, PMID 35575051, PMID 35575974, PMID 35961362, PMID 36064670, PMID 37283972, PMID 37368349, PMID 37652822, PMID 37774729, PMID 38388236, PMID 38400200, PMID 39088987, PMID 39146859, PMID 41295459, PMID 42610930
2014 (2), 2015 (1)