6 recruiting, 5 completed, 5 not yet recruiting, 2 unknown. 19 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 19 | Recruiting 6, Completed 5, Not yet recruiting 5, Unknown 2, Active not recruiting 1 |
Follow Multivessel Coronary Artery Disease: new trials by email Literature Review of Multivessel Coronary Artery Disease trials Research Report on Multivessel Coronary Artery Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Expand Management of Blood Pressure With Renal Denervation in Patients Undergoing Staged PCI for Advanced Coronary Artery diseasE Renal denervation - Multivessel Coronary Artery Disease, Hypertension Resistant to Conventional Therapy | Not applicable | Not yet recruiting | Ceric Sàrl | 1000 | 2026-11-01 | 2026-05-22 |
| The CORE - μFR Clinical Trial Angiography-guided PCI, μFR based-PCI - Acute Coronary Syndromes (ACS), NSTEMI - Non-ST-Segment Elevation Myocardial Infarction | Not applicable | Not yet recruiting | University of Roma La Sapienza | 350 | 2026-05-18 | 2026-05-22 |
| Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL) CABG, PCI - Coronary Artery Disease, Coronary Artery Disease (CAD) | Not applicable | Recruiting | University Medical Center Groningen | 358 | 2026-05-01 | 2026-05-12 |
| Revascularization Strategies in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome (NSTE-ACS) and Severe Coronary Artery Disease PCI, CABG - Multivessel Coronary Artery Disease, Acute Coronary Syndrome | Not applicable | Recruiting | American Heart of Poland | 1000 | 2025-08-25 | 2026-07-08 |
| Ticin Pilot Study: Sirolimus-Eluting Balloon for Stabilization and Regression of Non-Obstructive Coronary Plaques. Sirolimus drug eluting ballooon therapy, Optimal guidelines-directed medical therapies (GDMT) - Coronary Arterial Disease (CAD), Vulnerable Coronary Plaques | Not applicable | Not yet recruiting | Cardiocentro Ticino | 24 | 2025-04-01 | 2025-04-15 |
| Multivessel Balloon Occlusion to Investigate Obstructive Coronary Artery Disease and aNgina Percutaneous coronary intervention (PCI), Symptom assessment during experimentally induced ischaemia - Stable Angina, Multivessel Coronary Artery Disease | Not applicable | Recruiting | Imperial College London | 50 | 2024-06-13 | 2026-10-28 |
| Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery Coronary Artery Bypass Graft, Robotically-assisted minimally-invasive direct coronary artery bypass, Percutaneous Coronary Intervention - Coronary Artery Disease, Multivessel Coronary Artery Disease | Not applicable | Not yet recruiting | Cardiology Research UBC | 80 | 2024-05-01 | 2024-04-23 |
| Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI Culprit-lesion revascularization, Non-culprit-lesion revascularization - Non-ST-elevation Myocardial Infarction, Multivessel Coronary Artery Disease | Not applicable | Recruiting | Leipzig Heart Science gGmbH | 3390 | 2023-10-27 | 2025-01-16 |
| Complete Revascularization Via Inferior Part-sternotomy Inferior part-sternotomy, Full median sternotomy - Complete Revascularization, Coronary Artery Bypass Grafting | Not applicable | Not yet recruiting | China National Center for Cardiovascular Diseases | 260 | 2023-05-05 | 2023-04-28 |
| Temporary MCS With the iVAC 2L Transaortic Device in High-risk PCI iVAC 2L - Ischemic Cardiovascular Disease, Multivessel Coronary Artery Disease | Not applicable | Recruiting | National Medical Research Center for Cardiology, Ministry of Health of Russian Federation | 100 | 2023-02-17 | 2025-09-08 |
| The FAVOR V AMI Trial FAST Technique, Angiography - ST-Segment Elevation Myocardial Infarction, Multivessel Coronary Artery Disease | Not applicable | Recruiting | China National Center for Cardiovascular Diseases | 5000 | 2023-01-17 | 2026-09-24 |
| COMBINE-INTERVENE: COMBINEd Ischemia and Vulnerable Plaque Percutaneous INTERVENtion to Reduce Cardiovascular Events PCI revascularization strategy based on combined FFR and OCT assessment, PCI revascularization strategy based FFR assessment - Multivessel Coronary Artery Disease, Ischemia | Not applicable | Active not recruiting | Diagram B.V. | 1223 | 2022-03-16 | 2026-06-03 |
| Efficacy and Safety of One-Stage Hybrid Coronary Revascularization coronary revascularization - Multivessel Coronary Artery Disease | Not applicable | Unknown | Shanghai East Hospital | 200 | 2020-12-30 | 2021-03-23 |
| In-hospital Versus After-discharge Complete Revascularization In-hospital nonculprit-lesions percutaneous coronary intervention (PCI), After-discharge nonculprit-lesions percutaneous coronary intervention (PCI) - STEMI - ST Elevation Myocardial Infarction, Multivessel Coronary Artery Disease | Not applicable | Completed | Hospital General Universitario de Valencia | 250 | 2018-01-20 | 2023-04-24 |
| Myocardial Hybrid Revascularization Versus Coronary artERy Bypass GraftING for Complex Triple-vessel Disease Hybrid Revascularization, Conventional Coronary Artery Bypass Surgery - Multivessel Coronary Artery Disease | Not applicable | Unknown | InCor Heart Institute | 60 | 2014-08-01 | 2018-11-29 |
| Functional Testing Underlying Coronary Revascularisation invasive coronary angiography, Functional testing by fractional flow reserve measurement - Multivessel Coronary Artery Disease, Vessel Disease | Not applicable | Completed | Hospices Civils de Lyon | 941 | 2013-05-27 | 2025-09-26 |
| Comparison of the Biolimus A9-eluting Stent With the Zotarolimus -Eluting Stent in Multi-vessel PCI Percutaneous Coronary Intervention - Multivessel Coronary Artery Disease | Not applicable | Completed | Keimyung University Dongsan Medical Center | 932 | 2013-03-01 | 2021-09-01 |
| Comparison Between FFR Guided Revascularization Versus Conventional Strategy in Acute STEMI Patients With MVD. FFR-guided revascularisation strategy, randomised to guidelines group - Myocardial Infarction, Multivessel Coronary Artery Disease | Not applicable | Completed | Maasstad Hospital | 885 | 2011-07-01 | 2020-08-11 |
| Plasmonic Nanophotothermal Therapy of Atherosclerosis Transplantation of nanoparticles, Transplantation of iron-bearing nanoparticles, Stenting - Stable Angina, Heart Failure | Not applicable | Completed | Ural State Medical University | 180 | 2007-04-01 | 2021-03-17 |
Coronary Artery Disease (4) · Acute Coronary Syndrome (3) · Angina, Stable (3) · ST Elevation Myocardial Infarction (3) · Heart Failure (2) · Angina Pectoris (1) · Angina, Unstable (1) · Atherosclerosis (1) · Hypertension Resistant to Conventional Therapy (1) · Ischemia (1) · Myocardial Infarction (1) · Non-ST Elevated Myocardial Infarction (1) · Shock, Cardiogenic (1)
Cardiovascular Diseases (14) · Heart Diseases (14) · Myocardial Ischemia (14) · Vascular Diseases (14) · Pathological Conditions, Signs and Symptoms (10) · Pathologic Processes (7) · Infarction (6) · Ischemia (6) · Necrosis (6) · Arterial Occlusive Diseases (5) · Arteriosclerosis (5) · Myocardial Infarction (5) · Coronary Disease (4) · Chest Pain (3) · Neurologic Manifestations (3)
Percutaneous Coronary Intervention (5) · Coronary Artery Bypass (2) · Angiography (1) · Biomatrix preparation (1) · Coronary Angiography (1) · Stents (1) · Surgical Procedures, Operative (1)
China National Center for Cardiovascular Diseases (2) · American Heart of Poland (1) · Cardiocentro Ticino (1) · Cardiology Research UBC (1) · Ceric Sàrl (1) · Diagram B.V. (1) · Hospices Civils de Lyon (1) · Hospital General Universitario de Valencia (1) · Imperial College London (1) · InCor Heart Institute (1) · Keimyung University Dongsan Medical Center (1) · Leipzig Heart Science gGmbH (1) · Maasstad Hospital (1) · National Medical Research Center for Cardiology, Ministry of Health of Russian Federation (1) · Shanghai East Hospital (1)
Netherlands (4) · Germany (3) · Poland (3) · China (2) · France (2) · Italy (2) · Russia (2) · Spain (2) · Sweden (2) · Australia (1) · Austria (1) · Brazil (1) · Canada (1) · Czechia (1) · Denmark (1)
Alexander Kharlamov, M.D., FESC, FACC, FEACVI (1) · Bo Xu, MBBS (1) · Chang-Wook Nam, Postdoctoral (1) · Dmitry Pevzner, MD (1) · Elmir Omerovic, MD PhD (1) · Elvin Kedhi, Prof.dr. (1) · Erik Lipsic, Dr (1) · Eva Rumiz Gonzalez, MD, PhD (1) · Evgeniy Merkulov, MD (1) · Felix Mahfoud, Prof. (1) · Franz-Josef Neumann, MD PhD (1) · Gert Richardt, MD PhD (1) · Holger Thiele, MD, Prof. Dr. (1) · Jan Gabinsky, MD, PhD, DSc (1) · Krzysztof Sanetra, MD, PhD (1)
PMID 25864858, PMID 28317428, PMID 28644056, PMID 30823897, PMID 34736563, PMID 35045732, PMID 38743727, PMID 40097279, PMID 40209841, PMID 42276410, PMID 42866922