8 completed, 2 unknown, 1 active not recruiting, 1 recruiting. 6 Not applicable, 3 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 2, Unknown 2, Active not recruiting 1, Recruiting 1 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 4 | 1 | Completed 1 |
Follow Diagram B.V.: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| COMBINE-INTERVENE: COMBINEd Ischemia and Vulnerable Plaque Percutaneous INTERVENtion to Reduce Cardiovascular Events PCI revascularization strategy based on combined FFR and OCT assessment, PCI revascularization strategy based FFR assessment - Multivessel Coronary Artery Disease, Ischemia | Not applicable | Active not recruiting | Diagram B.V. | 1223 | 2022-03-16 | 2026-06-03 |
| Ultrasound Guided Transfemoral Complex Large-bore PCI Trial Ultrasound guided femoral access for complex PCI, Fluoroscopy guided femoral access for complex PCI - Complex Coronary Lesions, Percutaneous Coronary Intervention | Not applicable | Completed | Maatschap Cardiologie Zwolle | 544 | 2021-06-09 | 2023-06-18 |
| Rivaroxaban Plus Aspirin in Patients With Chronic Coronary Syndrome and High Ischemic Risk Rivaroxaban 2.5 MG [Xarelto] - Coronary Artery Disease (CAD), Peripheral Arterial Disease (PAD) | Completed | Maatschap Cardiologie Zwolle | 645 | 2020-12-21 | 2023-09-28 | |
| A Phase 2 Open Label Study to Assess the PK/PD Properties of RUC-4 in Patients With a ST-elevation Myocardial Infarction RUC-4 Compound - Coronary Disease, Myocardial Infarction | Phase 2 | Completed | CeleCor Therapeutics | 27 | 2020-06-02 | 2021-02-03 |
| Resting Full-cycle Flow Ratio (RFR) Versus Angiography to Guide Revascularization Strategy in Patients Undergoing Coronary Artery By-pass Grafting (CABG) RFR guided CABG, Angio guided CABG - Coronary Artery Disease | Not applicable | Recruiting | Diagram B.V. | 500 | 2020-02-03 | 2024-02-01 |
| Detection of Asymptomatic Atrial Fibrillation in Persons of 65 Year of Age or Older Subjects with asymptomatic atrial fibrillation will be screened by using a Mobile ECG Device - Atrial Fibrillation | Completed | Diagram B.V. | 2168 | 2018-07-02 | 2022-07-12 | |
| CFAE/Spatiotemporal Dispersion Guided Ablation Versus PVI Guided Ablation in Persistent AF CFAE guided ablation, PVI guided ablation - Chronic Atrial Fibrillation | Not applicable | Unknown | Diagram B.V. | 180 | 2016-10-12 | 2022-07-13 |
| Optical Coherence Tomography Morphologic and Fractional Flow Reserve Assessment in Diabetes Mellitus Patients Optical Coherence Tomography - Diabetes Mellitus, Coronary Artery Disease | Completed | Diagram B.V. | 550 | 2015-03-26 | 2021-09-05 | |
| Renal Nerve Stimulation and Renal Denervation in Patients With Sympathetic Ventricular Arrhythmias RNS and RDN - Arrhythmias, Cardiac | Phase 2 | Terminated | Diagram B.V. | 9 | 2015-03-03 | 2020-05-06 |
| Xience Versus Synergy in Left Main PCI Percutaneous coronary intervention, Dual antiplatelet therapy - Coronary Artery Disease | Not applicable | Unknown | NHS National Waiting Times Centre Board | 818 | 2014-12-01 | 2014-12-01 |
| Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent Treatment 90 days DAPT, Treatment 360 days DAPT - Acute Coronary Syndrome | Phase 4 | Completed | Diagram B.V. | 1500 | 2014-06-10 | 2019-02-08 |
| Treatment of Atrial Fibrillation in Patients by Pulmonary Vein Isolation in Combination With Renal Denervation or Pulmonary Vein Isolation Only procedure - Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation | Not applicable | Completed | Diagram B.V. | 145 | 2014-03-18 | 2022-07-12 |
| Renal Nerves Stimulation Study Electrical mapping, nerve stimulation checked renal denervation procedure, Electrial mapping, nerve stimulation guided renal denervation procedure - Hypertension, Renal Denervation | Phase 2 | Completed | Diagram B.V. | 56 | 2014-03-14 | 2020-05-06 |
Coronary Artery Disease (5) · Atrial Fibrillation (3) · Acute Coronary Syndrome (1) · Arrhythmias, Cardiac (1) · Coronary Disease (1) · Diabetes Mellitus (1) · Heart Diseases (1) · Hypertension (1) · Ischemia (1) · Myocardial Infarction (1) · Peripheral Arterial Disease (1) · ST Elevation Myocardial Infarction (1) · Vascular Diseases (1)
Aspirin (2) · 2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine (1) · Methods (1) · Percutaneous Coronary Intervention (1) · RUC-4 compound (1) · Rivaroxaban (1) · Single Person (1) · Therapeutics (1) · Ticagrelor (1) · Tomography, Optical Coherence (1)
Netherlands (10) · Belgium (2) · France (2) · Germany (2) · Japan (2) · Poland (2) · Slovakia (2) · Spain (2) · Australia (1) · Canada (1) · Denmark (1) · Estonia (1) · India (1) · Italy (1) · Malaysia (1)
Arif Elvan, MD, PhD (2) · E Kedhi, MD PhD (1) · Elvin Kedhi, Prof.dr. (1) · G. de Luca, Prof. dr. (1) · H. Suryapranata, Prof. dr. (1) · Jaap-Jan J. Smit, MD, PhD (1) · Maarten van Leeuwen, MD, PhD (1) · Rik Hermanides, MD, PhD (1)
PMID 34269911, PMID 34345911, PMID 34647513, PMID 35485232, PMID 36170036, PMID 38742577, PMID 38840580, PMID 39840429, PMID 40347200, PMID 42866922