22 terminated. 22 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 22 | Terminated 22 |
| Phase 2 | 7 | Terminated 7 |
Follow Mouth Diseases: new trials by email Literature Review of Mouth Diseases trials Research Report on Mouth Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Azithromycin on Failure Proportion of Severe Periodontitis Non-surgical Treatment Non-surgical periodontal treatment and azithromycin treatment, Non-surgical periodontal treatment and placebo treatment - Severe Chronic Periodontitis | Phase 3 | Terminated | University Hospital, Strasbourg, France | 6 | 2021-11-02 | 2024-08-20 |
| Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer. Clonidine HCl Mucoadhesive Buccal Tablet, Placebo Mucoadhesive Buccal Tablet - Chemoradiotherapy-Induced Severe Oral Mucositis | Phase 2 / Phase 3 | Terminated | Monopar Therapeutics | 190 | 2021-02-11 | 2023-05-31 |
| Caphosol Study: Prevention of Oral Mucositis in Children, Adolescents and Young Adults Receiving Chemotherapy Caphosol, Biotene - Oral Mucositis | Phase 3 | Terminated | Medical College of Wisconsin | 1 | 2016-10-01 | 2020-03-09 |
| Efficacy and Safety Study of Gevokizumab to Treat Behcet's Disease Uveitis Placebo, Gevokizumab - Behcet's Disease Uveitis | Phase 3 | Terminated | XOMA (US) LLC | 4 | 2014-11-01 | 2015-12-29 |
| Randomized Trial of Glutamine in Patients With Mucositis or Esophagitis Placebo, Glutamine, Questionnaires - Advanced Cancers | Phase 3 | Terminated | M.D. Anderson Cancer Center | 77 | 2014-07-10 | 2022-06-15 |
| Evaluation of Oral Morphine Gel in Oral Mucositis Induced by Chemotherapy in Children and Young Adults morphine gel, placebo gel - Cancer | Phase 3 | Terminated | University Hospital, Strasbourg, France | 25 | 2014-06-01 | 2026-03-16 |
| Assessment of Mucosal Activity to Improve the Prognosis of Patients With Crohn's Disease Treated With Immunosuppressants ADALIMUMAB, Placebo - Crohn's Disease, Mucosal Inflammation | Phase 3 | Terminated | Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa | 15 | 2012-10-01 | 2016-05-04 |
| A Clinical Trial for CTD-ILD Treatment N-Acetylcysteine - Interstitial Lung Disease, Connective Tissue Disease | Phase 2 / Phase 3 | Terminated | University of Michigan | 5 | 2011-12-01 | 2017-04-06 |
| Prevention of Radiation-induced Severe Oral Mucositis in Oral Cavity, Oropharynx, Hypopharynx, and Cavum Cancer Homeodent®, 1.4% Sodium Bicarbonate solution - Oropharynx Cancer, Hypopharynx Cancer | Phase 3 | Terminated | Centre Leon Berard | 78 | 2009-05-01 | 2012-11-01 |
| Effect of Saliva Substitutes on Dental Hard Tissues in Situ Glandosane, Saliva natura - Hyposalivation | Phase 2 / Phase 3 | Terminated | Charite University, Berlin, Germany | 19 | 2009-01-01 | 2011-11-15 |
| A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal Neuralgia Amifostine, CyberKnife stereotactic radiosurgery - Trigeminal Neuralgia | Phase 3 | Terminated | Stanford University | 17 | 2008-09-01 | 2017-04-04 |
| A Study of ProQuad™ in Healthy Children in Korea (V221-023) Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live (ProQuad™), M-M-R™ II and Varivax™ - Measles, Mumps | Phase 3 | Terminated | Merck Sharp & Dohme LLC | 30 | 2008-02-01 | 2017-04-12 |
| Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen TOPICAL SIROLIMUS (RAPAMUNE*), TOPICAL BETAMETHASONE 0.05% - Oral Lichen Planus | Phase 3 | Terminated | University Hospital, Tours | 76 | 2008-02-01 | 2013-10-16 |
| EN3285 for the Prevention or Delay of Oral Mucositis in Patients With Head and Neck Cancer EN3285, Placebo, Standard of care - Oral Mucositis, Head and Neck Cancer | Phase 3 | Terminated | Endo USA Inc., a Keenova Therapeutics Company | 240 | 2007-12-01 | 2013-09-20 |
| A Study of High-Risk Oral Cavity Cancer Thalidomide, Celebrex, Cyclophosphamide, Dexamethasone - Oral Cavity Cancer | Phase 2 / Phase 3 | Terminated | National Health Research Institutes, Taiwan | 150 | 2007-06-01 | 2015-02-25 |
| OraTest in Combination With Visual Examination and Visual Examination Alone Visual Examination, OraTest - Head And Neck Cancer, Oropharynx Cancer | Phase 3 | Terminated | M.D. Anderson Cancer Center | 1 | 2006-11-01 | 2016-05-13 |
| Palifermin in Lessening Oral Mucositis in Patients Undergoing Radiation Therapy and Chemotherapy for Locally Advanced Head and Neck Cancer palifermin, cisplatin, placebo - Head and Neck Cancer, Mucositis | Phase 3 | Terminated | Radiation Therapy Oncology Group | 21 | 2006-07-01 | 2017-12-26 |
| Study of Proxinium Plus Best Supportive Care Versus Best Supportive Care for Patients With Advanced Head and Neck Cancer Proxinium - Carcinoma, Squamous Cell of Head and Neck, Carcinoma, Squamous Cell | Phase 2 / Phase 3 | Terminated | Sesen Bio, Inc. | 165 | 2005-12-01 | 2015-12-23 |
| Lamictal in the Treatment of Post-Herpetic Neuralgia Lamictal in the treatment of Post-Herpetic Neuralgia - Neuralgia, Postherpetic | Phase 2 / Phase 3 | Terminated | George Washington University | 2005-02-01 | 2013-03-13 | |
| Periodontal Infection and Prematurity Study Scaling and root planing - Periodontal Diseases, Premature Birth | Phase 3 | Terminated | University of Pennsylvania | 2100 | 2004-10-01 | 2016-08-15 |
Showing 20 of 22. Sign in to see all of them.
Mucositis (6) · Head and Neck Neoplasms (5) · Stomatitis (4) · Mouth Neoplasms (3) · Neoplasms (3) · Oropharyngeal Neoplasms (3) · Carcinoma, Squamous Cell (2) · Pain (2) · Squamous Cell Carcinoma of Head and Neck (2) · Arthritis, Rheumatoid (1) · Behcet Syndrome (1) · Chickenpox (1) · Chronic Periodontitis (1) · Connective Tissue Diseases (1) · Crohn Disease (1)
Stomatognathic Diseases (22) · Neoplasms (7) · Neoplasms by Site (7) · Digestive System Diseases (6) · Gastroenteritis (6) · Gastrointestinal Diseases (6) · Pathological Conditions, Signs and Symptoms (4) · Skin Diseases (4) · Skin and Connective Tissue Diseases (4) · Carcinoma (3) · Neoplasms by Histologic Type (3) · Neoplasms, Glandular and Epithelial (3) · Nervous System Diseases (3) · Neurologic Manifestations (3)
Acetylcysteine (1) · Adalimumab (1) · Amifostine (1) · Biotene (1) · Celecoxib (1) · Chemotherapy, Adjuvant (1) · Chickenpox Vaccine (1) · Cisplatin (1) · Cyclophosphamide (1) · Dexamethasone (1) · Fibroblast Growth Factor 7 (1) · Glandosane (1) · Glutamine (1) · Ketamine (1) · Lamotrigine (1)
M.D. Anderson Cancer Center (2) · University Hospital, Strasbourg, France (2) · Assistance Publique - Hôpitaux de Paris (1) · Centre Leon Berard (1) · Charite University, Berlin, Germany (1) · Endo USA Inc., a Keenova Therapeutics Company (1) · George Washington University (1) · Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa (1) · Medical College of Wisconsin (1) · Merck Sharp & Dohme LLC (1) · Monopar Therapeutics (1) · National Health Research Institutes, Taiwan (1) · Radiation Therapy Oncology Group (1) · Sesen Bio, Inc. (1) · Stanford University (1)
United States (11) · France (9) · Germany (3) · Spain (3) · Argentina (1) · Belgium (1) · Brazil (1) · Canada (1) · Croatia (1) · Hungary (1) · India (1) · Israel (1) · Italy (1) · Mexico (1) · Poland (1)
Aung Naing, MD (1) · Clara Choi (1) · David I. Rosenthal, MD (1) · George A Macones, M.D. (1) · Georges Bettega, Dr (1) · Holli Carlson (1) · Mark Chambers, DMD (1)
PMID 20840689, PMID 21477333, PMID 33580845
2008 (1)