4 recruiting, 2 completed, 2 withdrawn, 1 active not recruiting. 9 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 9 | Recruiting 4, Completed 2, Withdrawn 2, Active not recruiting 1 |
Follow Mouth Abnormalities: new trials by email Literature Review of Mouth Abnormalities trials Research Report on Mouth Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery Methadone hydrochloride, Fentanyl/Hydromorphone - Cleft Palate, Pain | Phase 4 | Recruiting | Duke University | 60 | 2025-06-04 | 2026-04-14 |
| Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate Nebulization of dexmedetomidine and ketamine, Nebulization of dexmedetomidine - Sedation, Emergence Delirium | Phase 4 | Recruiting | Assiut University | 60 | 2024-04-10 | 2025-10-03 |
| Ketorolac in Palatoplasty Ketorolac, Placebo - Cleft Lip and Palate | Phase 4 | Recruiting | The University of Texas Health Science Center, Houston | 74 | 2021-09-17 | 2026-02-19 |
| Cost Effectiveness in Alveolar Bone Grafting in Patients With Cleft Lip and Palate Intervention group (DBM/BMP), Control group(autologous ICBG) - Cleft Lip and Palate | Phase 4 | Recruiting | The University of Texas Health Science Center, Houston | 40 | 2021-06-14 | 2026-02-19 |
| The Use of Fibrin Sealant to Reduce Post Operative Pain in Cleft Palate Surgery Tisseel - Cleft Palate | Phase 4 | Withdrawn | University of Alberta | 2019-09-01 | 2022-05-20 | |
| Evaluation of Trigeminal Nerve Blockade Ropivacaine, Sham Comparator - Mouth Abnormalities, Cleft Palate | Phase 4 | Active not recruiting | University of Florida | 40 | 2018-11-20 | 2026-07-21 |
| Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair Dexmedetomidine, Placebo - Cleft Palate | Phase 4 | Withdrawn | Baylor College of Medicine | 2017-12-31 | 2019-02-05 | |
| Dexmedetomidine as Adjuvant for Bupivacaine in Ultrasound Guided Infraorbital Nerve Block for Cleft Lip Repair Dexmedetomidine group, Dexamethasone group - Cleft Lip | Phase 4 | Completed | Mansoura University | 44 | 2017-08-01 | 2020-09-07 |
| Acid Tranexamic Effectiveness in Reducing the Intraoperative Bleeding in Palatoplasty Tranexamic Acid, Saline - Cleft Palate, Hemorrhage | Phase 4 | Completed | Professor Fernando Figueira Integral Medicine Institute | 66 | 2013-12-01 | 2015-04-21 |
Cleft Palate (6) · Cleft Lip (3) · Pain (2) · Agnosia (1) · Congenital Abnormalities (1) · Emergence Delirium (1) · Hemorrhage (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (9) · Mouth Diseases (9) · Stomatognathic Diseases (9) · Stomatognathic System Abnormalities (9) · Congenital Abnormalities (8) · Craniofacial Abnormalities (6) · Jaw Abnormalities (6) · Jaw Diseases (6) · Maxillofacial Abnormalities (6) · Musculoskeletal Abnormalities (6) · Musculoskeletal Diseases (6) · Pathological Conditions, Signs and Symptoms (4) · Lip Diseases (3) · Neurologic Manifestations (3)
Sodium Chloride (2) · Dexmedetomidine (1) · Fentanyl (1) · Fibrin Tissue Adhesive (1) · Hydromorphone (1) · Ketamine (1) · Ketorolac (1) · Methadone (1) · Ropivacaine (1) · Tranexamic Acid (1)
The University of Texas Health Science Center, Houston (2) · Assiut University (1) · Baylor College of Medicine (1) · Duke University (1) · Mansoura University (1) · Professor Fernando Figueira Integral Medicine Institute (1) · University of Alberta (1) · University of Florida (1)
United States (4) · Egypt (2) · Canada (1)
Cameron R Smith, MD, PhD (1) · Chris D. Glover, MD (1) · Enas Abd el Motlb, MD (1) · Guilherme C Arantes (1) · Jaret L Olson, MD FRCSC (1) · Lisa M. Einhorn, M.D. (1) · Matthew Greives, MD (1) · Matthew R Grieves, MD,MS,FACS (1)