10 completed, 2 terminated, 1 withdrawn. 13 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Completed 10, Terminated 2, Withdrawn 1 |
Follow Morphine: new trials by email Literature Review of Morphine trials Research Report on Morphine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Oliceridine Analgesia on Postoperative Nause and Vomiting Oliceridine, Morphine - Laparoscopic Colorectal Surgery, Postoperative Analgesia | Phase 4 | Completed | Peking University First Hospital | 252 | 2024-07-02 | 2026-06-24 |
| Rescue Quadratus Lumborum Blocks for Post-cesarean Pain Saline, Bupivacaine, Dexamethasone - Morphine, Analgesics | Phase 4 | Withdrawn | The University of Texas Health Science Center, Houston | 2022-01-01 | 2023-11-03 | |
| Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine 2% lidocaine with 1:200,000 epinephrine and epidural morphine, 3% 2-chloroprocaine and epidural morphine - Physiological Effect of Drugs, Morphine | Phase 4 | Completed | The University of Texas Health Science Center, Houston | 44 | 2020-05-11 | 2022-05-26 |
| MORphine Use in the Fascia Iliaca Compartment Block With UltraSound Levobupivacaine, Placebo, Acetaminophen - Humans, Anesthetics, Local | Phase 4 | Terminated | Zuyderland Medisch Centrum | 55 | 2019-01-28 | 2021-05-06 |
| PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery. Ketamine-Morphine, Morphine - Ketamine, Morphine | Phase 4 | Completed | National University of Malaysia | 60 | 2018-04-05 | 2023-08-24 |
| PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery Ketamine-Morphine, Morphine - Ketamine, Morphine | Phase 4 | Completed | Universiti Kebangsaan Malaysia Medical Centre | 60 | 2018-04-05 | 2023-09-01 |
| Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery. Morphine intrathecal, Bupivacaine + Sufentanil epidural, Morphine intravenous - Analgesia, Patient-Controlled, Epidural Analgesia | Phase 4 | Completed | Charles University, Czech Republic | 75 | 2017-04-10 | 2019-01-31 |
| Methylnaltrexone as a Method to Improve Ticagrelor Uptake in Morphine Treated STEMI Patients Methylnaltrexone bromide (Relistor®)., Sodium Chloride 9mg/mL - STEMI, Morphine | Phase 4 | Completed | Karolinska University Hospital | 82 | 2016-11-01 | 2018-04-09 |
| Spinal Morphine in Robotic Assisted Radical Prostatectomy Morphine, Lidocaine - Morphine, Injections, Spinal | Phase 4 | Completed | Maasstad Hospital | 160 | 2016-09-01 | 2018-08-07 |
| Palliation of Dyspnea With Morphine in Patients With Interstitial Lung Disease Morphine hydrochloride, Placebo - Interstitial Lung Disease, Dyspnea | Phase 4 | Completed | University of Aarhus | 36 | 2016-01-01 | 2019-04-10 |
| RCT Comparing Analgesia Post-VATS With Epimorph VS Placebo Intrathecal Morphine/Sufentanil, PCA - Thoracic Surgery, Video-assisted, Postoperative Pain | Phase 4 | Terminated | Université de Sherbrooke | 34 | 2013-04-01 | 2016-01-20 |
| Epidural Low Dose Morphine in Postoperative Pain After Posterior Lumbar Spinal Surgery 1 mg morphine soak in epidural oxidized cellulose, normal saline - Morphine | Phase 4 | Completed | Mahidol University | 19 | 2012-08-01 | 2014-02-20 |
| Peri -and Postoperative Drug Therapy Schedules for Morbidly Obese Patients Atracurium, TBW - Obese, Atracurium | Phase 4 | Completed | St. Antonius Hospital | 20 | 2009-11-01 | 2010-10-13 |
Pain, Postoperative (3) · Agnosia (2) · Dyspnea (1) · Emergencies (1) · Femoral Fractures (1) · Hip Fractures (1) · Lung Diseases, Interstitial (1) · Obesity (1) · Pain (1) · Patient Satisfaction (1) · Postoperative Nausea and Vomiting (1) · ST Elevation Myocardial Infarction (1)
Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (8) · Pathologic Processes (6) · Neurologic Manifestations (5) · Postoperative Complications (4) · Pain (3) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Behavior (1) · Body Weight (1) · Cardiovascular Diseases (1) · Disease Attributes (1) · Fractures, Bone (1) · Health Behavior (1)
Morphine (6) · Analgesia, Patient-Controlled (2) · Bupivacaine (2) · Lidocaine (2) · Sodium Chloride (2) · Sufentanil (2) · ((3-methoxythiophen-2-yl)methyl)((2-(9-(pyridin-2-yl)-6-oxaspiro(4.5)decan-9-yl)ethyl))amine (1) · Acetaminophen (1) · Analgesia, Epidural (1) · Atracurium (1) · Dexamethasone (1) · Epinephrine (1) · Injections (1) · Levobupivacaine (1) · Passive Cutaneous Anaphylaxis (1)
The University of Texas Health Science Center, Houston (2) · Charles University, Czech Republic (1) · Karolinska University Hospital (1) · Maasstad Hospital (1) · Mahidol University (1) · National University of Malaysia (1) · Peking University First Hospital (1) · St. Antonius Hospital (1) · Universiti Kebangsaan Malaysia Medical Centre (1) · University of Aarhus (1) · Université de Sherbrooke (1) · Zuyderland Medisch Centrum (1)
Netherlands (3) · Malaysia (2) · United States (2) · Canada (1) · China (1) · Czechia (1) · Denmark (1) · Sweden (1) · Thailand (1)
Linden Lee, MD (2) · Aart Jan W Teunissen, MD (1) · Chian Yong Liu, MMed (Anaes) (1) · Dong-Xin Wang, PHD (1) · Jiri Malek, M.D. (1) · Loghman Henareh, MD; PhD (1) · Mark V Koning, MD, DESA (1) · Nawzad Saleh, MD, PhD (1) · Per Tornvall, MD, PhD (1) · Sanne Postma, MD (1) · Seppe Koopman, MD, PhD (1) · Simone van Kralingen, MD (1) · Ulf Jensen, MD, PhD (1) · Yanick Sansoucy (1) · Yong C Liu, MMed (Anaes) (1)
PMID 1015603, PMID 10740539, PMID 11331167, PMID 11331334, PMID 11374619, PMID 11472277, PMID 12411815, PMID 12548273, PMID 12560416, PMID 14622770, PMID 16846542, PMID 17138203, PMID 17413915, PMID 18686750, PMID 18762870, PMID 19157368, PMID 19174373, PMID 19690943, PMID 22506940, PMID 23300227, PMID 23569691, PMID 23788067, PMID 23878064, PMID 24157979, PMID 25304008, PMID 2589650, PMID 26330019, PMID 26759680, PMID 27714758, PMID 27787895, PMID 28420629, PMID 28510797, PMID 30426190, PMID 30636504, PMID 30881102, PMID 31162798, PMID 31388805, PMID 31567573, PMID 31845316, PMID 32467512, PMID 32703194, PMID 33025536, PMID 33210266, PMID 33238043, PMID 34351590, PMID 36534717, PMID 36909334, PMID 37556070, PMID 37629444, PMID 37892882
2015 (1), 2016 (1)