43 completed, 16 unknown, 9 recruiting, 5 not yet recruiting. 45 Not applicable, 6 Phase 3, 4 Phase 1, 4 Phase 2, 3 Phase 4.
Follow Lower Back Pain: new trials by email Literature Review of Lower Back Pain trials Research Report on Lower Back Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Semaglutide for Low Back Pain Semaglutide (administered by PDS290 pen-injector), Placebo (administered by PDS290 pen-injector) - Lower Back Pain, Obesity (BMI>30) | Phase 2 | Not yet recruiting | Washington University School of Medicine | 250 | 2027-02-01 | 2026-07-28 |
| Adia Med of Winter Park LLC Lower Back Pain Research Study Umbilical Cord Blood-Derived Stem Cells and Exosomes, Placebo IV - Chronic Mechanical Lower Back Pain, Lower Back Pain | Phase 1 | Recruiting | Adia Med of Winter Park LLC | 100 | 2026-06-16 | 2026-06-17 |
| Association Between Trendelenburg Sign and Lumbar MRI Abnormalities Facet Joint Arthropathy, Lower Back Pain | Not yet recruiting | Bahçeşehir University | 120 | 2026-06-04 | 2026-06-10 | |
| Investigating Medical Massage Therapy for Patients With Sub-Acute Lower Back Pain Medical Massage Therapy, Provider Directed Care - Lower Back Pain, Subacute Lower Back Pain | Not applicable | Recruiting | The Geneva Foundation | 220 | 2026-06-01 | 2026-06-05 |
| Low Back and Neck Pain in Nursing Students at The University of The West Indies Clinical Control Group (Group A), Spine Exercise Program (Group B) - Back Pain, Low Back Pain | Not applicable | Not yet recruiting | The University of The West Indies | 400 | 2026-04-01 | 2026-02-24 |
| Safety and PK of Intrathecal CNTX-3001 for Intractable Chronic Low Back Pain CNTX-3001, Placebo - Lower Back Pain | Phase 1 | Recruiting | Centrexion Therapeutics | 16 | 2026-03-01 | 2026-03-23 |
| Electronic Approach to the Human Massage Therapist EMMA massage therapy, Clinical massage treatment - Lower Back Pain | Not applicable | Recruiting | Mayo Clinic | 40 | 2026-01-30 | 2026-10-15 |
| Peripheral Nerve Stimulation With the SPRINT® System in Chronic PSIJC Pain SPRINT PNS System - Lower Back Pain | Not applicable | Recruiting | Medical University of South Carolina | 10 | 2025-10-26 | 2025-11-14 |
| Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques Dry Needling, Dry needling with high-rate PENS, Dry needling with low-rate PENS - Pain, Back Pain | Not applicable | Recruiting | The University of Texas Medical Branch, Galveston | 42 | 2025-10-23 | 2026-08-17 |
| The Effects of Balanced Seating Pressure on Pelvic Asymmetry: A Pilot Study Dasuit Cusion, Placebo, Washout - Lower Back Pain, Scoliosis Patients | Not applicable | Completed | Chang Gung Memorial Hospital | 20 | 2025-09-12 | 2026-06-12 |
| Bone Enhanced Ultrasound (BEUS) Data Library Development Project spinal ultrasound - Lower Back Pain, Facet Joint Pain; Low Back Pain | Not yet recruiting | Queen's University | 100 | 2025-09-01 | 2025-07-29 | |
| Effect of Dynamic Sitting on Pain Development - Part 2 Dynamic office chair (saddle chair with standard pendulum mechanism), Dynamic Office Chair (office swivel chair with integrated newly developed pendulum mechanism) - Lower Back Pain | Not applicable | Recruiting | University of Applied Sciences for Health Professions Upper Austria | 20 | 2025-05-12 | 2025-09-29 |
| Qutenza 8% Capsaicin Topical System for the Treatment of Neuropathic Axial Lower Back Pain and Lumbosacral Radiculopathy Qutenza® 8% Capsaicin Topical System - Lower Back Pain, Lumbosacral Radiculopathy | Enrolling by invitation | Medical University of South Carolina | 50 | 2025-03-13 | 2026-03-20 | |
| The Effect of Kinesio Taping Applied to Operating Room Nurses on Low Back Pain, Fatigue, and Sleep Quality Kinesiotape Application - Lower Back Pain, Kinesio Taping | Not applicable | Not yet recruiting | Nigde Omer Halisdemir University | 100 | 2025-01-01 | 2025-01-06 |
| Effects of a Lower Back Wrap Device on Lower Back Pain, Physical Function, and Quality of Life Low back pain wrap - Lower Back Pain, Lower Back Pain Chronic | Not applicable | Completed | State University of New York at Buffalo | 153 | 2024-12-02 | 2025-08-13 |
| Anxiety Level Among Patients With Chronic Low Back Pain Anxiety Disorders, Anxiety Disorders and Symptoms | Completed | Medical University of Silesia | 202 | 2024-11-27 | 2026-05-19 | |
| Measuring Reliability of Spine Mobilization in Low Back Pain Spinal mobilization - Low Back Pain, Low Back Ache | Completed | University of Kansas Medical Center | 50 | 2024-10-02 | 2026-05-13 | |
| Precise and Objective Identification of Bertolotti Syndrome Using Novel Kinematic Biomarkers Bertolotti's Syndrome, Lower Back Pain | Active not recruiting | The Cleveland Clinic | 40 | 2024-01-17 | 2026-04-08 | |
| What Are Persistent Lower Back Pain Patients' Views of Sleep Health Within an Outpatient Musculoskeletal Physiotherapy Setting? Interview - Persistent Lower Back Pain, Sleep Disturbance | Unknown | Sheffield Hallam University | 10 | 2023-12-01 | 2023-10-23 | |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
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Low Back Pain (78) · Back Pain (15) · Pain (8) · Chronic Pain (6) · Neck Pain (5) · Intervertebral Disc Degeneration (4) · Musculoskeletal Pain (4) · Osteoarthritis (4) · Arthralgia (3) · Marijuana Abuse (3) · Myalgia (3) · Osteoarthritis, Knee (3) · Radiculopathy (3) · Agnosia (2) · Arthritis, Rheumatoid (2)
Neurologic Manifestations (78) · Pathological Conditions, Signs and Symptoms (78) · Signs and Symptoms (78) · Pain (70) · Back Pain (63) · Musculoskeletal Diseases (18) · Nervous System Diseases (13) · Neuromuscular Diseases (9) · Joint Diseases (7) · Mental Disorders (7) · Muscular Diseases (7) · Arthritis (6) · Bone Diseases (6) · Peripheral Nervous System Diseases (6) · Spinal Diseases (6)
Transcutaneous Electric Nerve Stimulation (3) · Carisoprodol (2) · Control Groups (2) · Musculoskeletal Manipulations (2) · Braces (1) · Capsaicin (1) · Computed Tomography Angiography (1) · Dry Needling (1) · Ice (1) · Interviews as Topic (1) · Music Therapy (1) · Myofascial Release Therapy (1) · Naltrexone (1) · Physical Therapy Modalities (1) · Pregnenolone (1)
Medical University of South Carolina (3) · Apurano Pharmaceuticals GmbH (2) · Chang Gung Memorial Hospital (2) · Meda Pharmaceuticals (2) · The University of The West Indies (2) · University of Applied Sciences for Health Professions Upper Austria (2) · Adia Med of Winter Park LLC (1) · Annette C. Toledano MD (1) · Assistance Publique Hopitaux De Marseille (1) · Bahçeşehir University (1) · Baylis Medical Company (1) · Benjamin L. England and Associates, LLC (1) · Benvenue Medical, Inc. (1) · Boston Medical Center (1) · Brigham and Women's Hospital (1)
United States (36) · Germany (5) · Austria (3) · Canada (3) · France (3) · Taiwan (3) · Israel (2) · Jamaica (2) · Malaysia (2) · Norway (2) · Pakistan (2) · South Korea (2) · Switzerland (2) · Turkey (Türkiye) (2) · Belgium (1)
Lewis M. Fredane, MD (2) · Afifa Safdar, PhD* (1) · Alphonse Lubansu, M.D. (1) · Ameet Nagpal (1) · Anna-Christina Bevelaqua, M.D (1) · Annette C Toledano, MD (1) · Arnaud Dupeyron, MD, PhD (1) · Aslam Khan, DC (1) · Bahman Jabbari, MD (1) · Bernhard Schwartz, Dr. BSc MSc (1) · Bruce Vrooman, M.D. (1) · Burel R Goodin, PhD (1)
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1IK2RX000908-01A1 (1), 1UG3NS123965-01 (1), K12NS130673 (1), K23AT010487 (1), R21DA044503 (1)