7 terminated. 7 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Terminated 7 |
Follow Liver Failure: new trials by email Literature Review of Liver Failure trials Research Report on Liver Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DAA Treatment in Donor HCV-positive to Recipient HCV-negative Liver Transplant Treatment with Direct Acting Antiviral tablet - End Stage Liver Disease, Hepatitis C | Phase 4 | Terminated | Massachusetts General Hospital | 33 | 2017-11-21 | 2022-07-28 |
| Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic Encephalopathy Placebo, Rifaximin - Hepatic Encephalopathy | Phase 4 | Terminated | Bausch Health Americas, Inc. | 6 | 2013-04-03 | 2024-01-09 |
| Quality of Life and Nutritional Improvements in Cirrhotic Patients Rifaximin, Lactulose, Lactulose Placebo - Liver Cirrhosis, Hepatic Encephalopathy | Phase 4 | Terminated | Tampa General Hospital | 4 | 2013-04-01 | 2013-09-23 |
| Effect of Intrathoracic Pressure Regulation on Traumatic Brain Injury -7 cm H2O ITPR, -12cm H2O ITPR - Head Injury | Phase 4 | Terminated | Advanced Circulatory Systems | 1 | 2012-08-01 | 2015-02-16 |
| Study of N-Acetylcysteine in Acute Liver Failure (ALF) N-acetylcysteine - Acute Liver Failure, Fulminant Hepatic Failure | Phase 4 | Terminated | University of Texas Southwestern Medical Center | 255 | 2008-12-01 | 2020-06-01 |
| Trial of Calcineurin Inhibitor-Sparing Immunosuppression Regimen in Pediatric Liver Transplantation mycophenolate mofetil, placebo medication - End-stage Liver Disease, Renal Insufficiency | Phase 4 | Terminated | Baylor College of Medicine | 13 | 2004-11-01 | 2020-03-13 |
| Orthotopic Liver Transplantation Using a Living Donor donor right hepatic lobectomy - Liver Disease, Liver Neoplasms | Phase 4 | Terminated | University of Chicago | 20 | 2000-04-01 | 2013-09-27 |
End Stage Liver Disease (3) · Hepatic Encephalopathy (3) · Liver Diseases (3) · Brain Diseases (1) · Brain Injuries, Traumatic (1) · Craniocerebral Trauma (1) · Fibrosis (1) · Hepatic Insufficiency (1) · Hepatitis C (1) · Hydrocephalus (1) · Hypertension, Portal (1) · Intracranial Hemorrhages (1) · Liver Cirrhosis (1) · Liver Failure, Acute (1)
Digestive System Diseases (7) · Hepatic Insufficiency (6) · Liver Diseases (4) · Brain Diseases, Metabolic (3) · Central Nervous System Diseases (3) · Metabolic Diseases (3) · Nervous System Diseases (3) · Nutritional and Metabolic Diseases (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Brain Diseases (2) · Blood-Borne Infections (1) · Brain Injuries (1) · Cardiovascular Diseases (1)
Rifaximin (2) · Acetylcysteine (1) · Lactulose (1) · Mycophenolic Acid (1) · Sugars (1) · Therapeutics (1)
Advanced Circulatory Systems (1) · Bausch Health Americas, Inc. (1) · Baylor College of Medicine (1) · Massachusetts General Hospital (1) · Tampa General Hospital (1) · University of Chicago (1) · University of Texas Southwestern Medical Center (1)
United States (6)
Guy Neff, MD, MBA (1) · J. Michael Millis, MD (1) · John Goss, MD (1) · Raymond Chung, MD (1) · Varsha Bhatt, Ph.D. (1) · William M Lee, MD (1)