5 active not recruiting. 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Active not recruiting 5 |
| Phase 1 | 2 | Active not recruiting 2 |
Follow Liver Failure: new trials by email Literature Review of Liver Failure trials Research Report on Liver Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RTX001 Autologous Engineered Macrophages for Liver Cirrhosis RTX001 - End-stage Liver Disease (ESLD), Cirrhosis, Liver | Phase 1 / Phase 2 | Active not recruiting | Resolution Therapeutics Limited | 30 | 2024-10-15 | 2026-10-05 |
| Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement Albumin Infusion - Cirrhosis, Hepatic Encephalopathy | Phase 2 | Active not recruiting | Hunter Holmes Mcguire Veteran Affairs Medical Center | 25 | 2023-11-02 | 2026-08-25 |
| TReatment for ImmUne Mediated PathopHysiology High-dose methylprednisolone, Equine anti-thymocyte globulin, Prednisolone - Acute Liver Failure, Fulminant Hepatic Failure | Phase 2 | Active not recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 44 | 2022-02-09 | 2026-08-12 |
| Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients QEL-001 - Rejection; Transplant, Liver, Liver Failure | Phase 1 / Phase 2 | Active not recruiting | Quell Therapeutics Limited | 33 | 2022-01-21 | 2026-07-02 |
| Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy Fecal Microbiota Transplant (FMT) oral capsules, Placebo oral capsule - Hepatic Encephalopathy | Phase 2 | Active not recruiting | Massachusetts General Hospital | 30 | 2018-04-01 | 2025-12-31 |
Hepatic Encephalopathy (4) · Liver Diseases (3) · Fibrosis (2) · End Stage Liver Disease (1) · Hepatic Insufficiency (1) · Inflammation (1) · Jaundice (1) · Liver Cirrhosis (1) · Liver Failure, Acute (1) · Rejection, Psychology (1)
Digestive System Diseases (5) · Brain Diseases (4) · Brain Diseases, Metabolic (4) · Central Nervous System Diseases (4) · Hepatic Insufficiency (4) · Metabolic Diseases (4) · Nervous System Diseases (4) · Nutritional and Metabolic Diseases (4) · Liver Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Behavior (1) · Hyperbilirubinemia (1) · Signs and Symptoms (1)
Albumins (1) · Antilymphocyte Serum (1) · Diphenhydramine (1) · Fecal Microbiota Transplantation (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1) · Prednisolone (1) · Sodium Chloride (1)
Hunter Holmes Mcguire Veteran Affairs Medical Center (1) · Massachusetts General Hospital (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Quell Therapeutics Limited (1) · Resolution Therapeutics Limited (1)
United States (3) · Spain (2) · United Kingdom (2) · Belgium (1)
Averell Sherker, MD (1) · Ed Doo, MD (1) · Estella M Alonso, MD (1) · Raymond T Chung, MD (1) · Valerie L Durkalski-Mauldin, PhD (1)
U01DK062436 (1)