32 completed, 11 unknown, 4 recruiting, 3 not yet recruiting. 10 Not applicable, 9 Phase 1, 8 Phase 4, 6 Phase 2, 2 Phase 3.
Follow Liver Dysfunction: new trials by email Literature Review of Liver Dysfunction trials Research Report on Liver Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Normothermic Oxygenated Perfusion (NMP) Viability Testing Before Transplantation of Discarded Livers NMP viability testing - Organ Transplantation, Liver Dysfunction | Phase 2 | Not yet recruiting | Rennes University Hospital | 99 | 2025-12-15 | 2025-08-15 |
| DEscripitive Patient Analysis to Enable Risk-based Quality Improvement Measures in a lArge iNternal mediCIne grouP Practice Liver Dysfunction, Thyroid | Not yet recruiting | Imed19 | 1000 | 2025-12-01 | 2025-05-07 | |
| Prevalence of Liver Dysfunction in Pediatric Patients With Congenital Heart Disease at Assiut. Ultrasonography, Blood Sampling - Congenital Heart Disease, Liver Dysfunction | Not applicable | Not yet recruiting | Assiut University | 40 | 2025-09-15 | 2025-08-27 |
| A Study of Lepodisiran (LY3819469) in Participants With Normal, Mild, Moderate, or Severe Liver Function Lepodisiran - Liver Dysfunction, Healthy | Phase 1 | Completed | Eli Lilly and Company | 30 | 2025-04-23 | 2026-08-19 |
| Assessing Changes in Gadoxetate Metabolism by the Liver Using MRI Liver Dysfunction | Completed | Sheffield Teaching Hospitals NHS Foundation Trust | 12 | 2024-12-02 | 2026-04-21 | |
| N-Acetyl Cysteine Effect on Liver Function After Mitral Valve Replacement N acetyl cysteine, normal saline - Oxidative Stress, Liver Dysfunction | Phase 4 | Completed | Kasr El Aini Hospital | 54 | 2024-06-30 | 2025-08-29 |
| Mecobalamin Combined With Ceftriaxone Sodium in the Treatment of Sepsis Liver Injury Mecobalamin, Ceftriaxone Sodium, Saline - Sepsis, Liver Dysfunction | Phase 4 | Unknown | Sichuan Provincial People's Hospital | 40 | 2024-01-15 | 2024-01-24 |
| Clinical Retrospective Study Analysis of Postoperative Complications Following Hepatectomy International Study Group for Liver Surgery (ISGLS) - Liver Failure, Liver Dysfunction | Unknown | Nanfang Hospital, Southern Medical University | 2000 | 2024-01-01 | 2024-08-01 | |
| SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury FibroScan® Expert 630 - End Stage Liver Disease, Jaundice | Recruiting | Nanfang Hospital, Southern Medical University | 411 | 2024-01-01 | 2025-05-21 | |
| Application of High-dose Insulin Therapy to Improve Liver Function and Regeneration High-Dose Insulin Therapy - Liver Dysfunction, Liver Metastasis Colon Cancer | Not applicable | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 70 | 2023-11-08 | 2024-11-20 |
| Endoscopic Ultrasound Guided Liver Biopsy and Portal Pressure Registry Liver Diseases, Liver Neoplasms | Withdrawn | Sheikh Shakhbout Medical City | 2023-04-01 | 2024-11-19 | ||
| FC Change From Day 1 to Day 3 Associated With SALD Fecal Calprotectin - Liver Dysfunction | Completed | Chinese Medical Association | 96 | 2023-01-01 | 2024-05-08 | |
| Pharmacokinetic Study of Anlotinib Hydrochloride Capsules in Healthy Subjects and Liver Dysfunction Patients Anlotinib Hydrochloride Capsule - Liver Dysfunction | Phase 1 | Unknown | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 30 | 2022-10-01 | 2022-09-29 |
| Global Utilization And Registry Database for Improved preservAtion of doNor Livers LIVERguard - Liver Diseases, Liver Dysfunction | Enrolling by invitation | Paragonix Technologies | 2000 | 2022-03-15 | 2026-09-17 | |
| Variants Of Intrahepatic Biliary Radicals in Nepali Population Magnetic Resonance Imaging - Liver Dysfunction | Completed | Grande International Hospital, Nepal | 384 | 2022-01-01 | 2025-01-27 | |
| Diaphragm Ultrasound to Evaluate the Antagonistic Effect of Sugammadex sugammadex - Diaphragm Ultrasonography, Liver Dysfunction | Phase 4 | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 99 | 2021-07-01 | 2021-09-05 |
| Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation Surgical Loupes, Microscope - Liver Failure, Liver Diseases | Not applicable | Completed | Istanbul Medipol University Hospital | 52 | 2020-12-02 | 2025-12-18 |
| Single-center Prospective Study of Non-invasive Methods for the Diagnosis of Postoperative Complications in Liver Transplant Recipients Rejection Acute Hepatic, Transplant; Failure, Liver | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 100 | 2020-07-06 | 2023-03-31 | |
| Role of Ajwa Derived Polyphenols in Dyslipidaemias Ajwa Date (phoenix dactylifera) - Dyslipidemias, Hyperglycemia | Not applicable | Unknown | Aga Khan University | 60 | 2019-03-20 | 2019-11-12 |
| An Investigational Study of BMS-986165 in Participants With Normal Liver Function and Participants With Mild to Severe Liver Damage BMS-986165 - Liver Dysfunction, Healthy Volunteers | Phase 1 | Completed | Bristol-Myers Squibb | 32 | 2019-02-26 | 2020-08-26 |
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Liver Diseases (53) · Liver Failure (6) · Hepatic Insufficiency (3) · Acute-On-Chronic Liver Failure (2) · Diabetes Mellitus, Type 2 (2) · Heart Failure (2) · Jaundice (2) · Liver Cirrhosis (2) · Liver Failure, Acute (2) · Liver Neoplasms (2) · Multiple Organ Failure (2) · Neoplasms (2) · Renal Insufficiency (2) · Agnosia (1) · Anemia (1)
Digestive System Diseases (52) · Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (8) · Hepatic Insufficiency (6) · Cardiovascular Diseases (4) · Endocrine System Diseases (4) · Glucose Metabolism Disorders (4) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Signs and Symptoms (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Digestive System Neoplasms (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Liver Failure (3)
Morphine (2) · Tacrolimus (2) · 4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazin-2-one (1) · Acetylcysteine (1) · Adrenal Cortex Hormones (1) · Amoxicillin (1) · Antilymphocyte Serum (1) · Asian ginseng (1) · Azithromycin (1) · Blood Specimen Collection (1) · Ceftriaxone (1) · Cisplatin (1) · Control Groups (1) · Dexamethasone (1) · Irinotecan (1)
Bristol-Myers Squibb (2) · Chinese Medical Association (2) · Nanfang Hospital, Southern Medical University (2) · Seoul National University Hospital (2) · Aga Khan University (1) · Assiut University (1) · Bausch Health Americas, Inc. (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · Chong Kun Dang Pharmaceutical (1) · Chuncheon Sacred Heart Hospital (1) · Dong-A ST Co., Ltd. (1) · Eli Lilly and Company (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Genzyme, a Sanofi Company (1) · Grande International Hospital, Nepal (1)
China (11) · United States (7) · South Korea (6) · Canada (3) · France (3) · Hungary (3) · United Kingdom (3) · Egypt (2) · Poland (2) · Taiwan (2) · Australia (1) · Austria (1) · Belgium (1) · Croatia (1) · Czechia (1)
Antonio Liguori, MD (1) · Argyro Fassoulaki, MD,PhD,DEAA (1) · Benjamin Rea (1) · Chun Pan, ph.D (1) · Dana Tomescu, Prof (1) · Duaa Raafat, Professor (1) · Felicity Williams (1) · Guido Beldi, MD (1) · Hai Li (1) · Hui-Chuan Sun, MD (1) · James Ferguson, phD (1)
PMID 11231856, PMID 1506645, PMID 17464971, PMID 20940288, PMID 22643348, PMID 23474284, PMID 23863086, PMID 23913844, PMID 24224656, PMID 24607624, PMID 26047908, PMID 26176387, PMID 27476767, PMID 28209134, PMID 28223101, PMID 28928275, PMID 29140542, PMID 29358444, PMID 29471812, PMID 29653741, PMID 29729368, PMID 30345856, PMID 30420883, PMID 30819510, PMID 31172417, PMID 31444849, PMID 32090446, PMID 32109631, PMID 32121065, PMID 32911703, PMID 33039403, PMID 33042916, PMID 33419900, PMID 33595110, PMID 33841012, PMID 33935773, PMID 34090929, PMID 34412498, PMID 34780106, PMID 34904404, PMID 35037228, PMID 35047957, PMID 35105573, PMID 35120736, PMID 36052222, PMID 36356684, PMID 37517452, PMID 38686365, PMID 39780312, PMID 40630620
2016 (1), 2017 (1), 2018 (1)