250 completed, 128 unknown, 79 recruiting, 38 not yet recruiting. 588 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 588 | Completed 250, Unknown 128, Recruiting 79, Not yet recruiting 38, Active not recruiting 30, Terminated 27, Withdrawn 21, Enrolling by invitation 13, Suspended 2 |
Follow Knee Injuries: new trials by email Literature Review of Knee Injuries trials Research Report on Knee Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Reducing Disparities in Knee Arthroscopy for Adolescents Educational program and patient navigator - Knee Injury, ACL Injury | Not applicable | Not yet recruiting | Ann & Robert H Lurie Children's Hospital of Chicago | 80 | 2027-10-01 | 2026-06-18 |
| Intraoperative Analysis of Knee Kinematics During ACL Reconstruction - an Exploratory Study Knee Cinematics - ACL - Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 30 | 2027-07-01 | 2026-06-18 |
| Exercise Program for ITB Syndrome Individualized Exercise Program, Standard Physical Therapy - Iliotibial Band Syndrome | Not applicable | Not yet recruiting | NYU Langone Health | 100 | 2027-03-01 | 2026-08-07 |
| Personalized Weight-Bearing With Smart Crutch Tips After Surgery for Tibial Plateau Fractures Crutch Tip Biofeedback System, Individualized FEA-Guided Postoperative Weight-Bearing, Usual-Care Postoperative Weight-Bearing - Tibial Plateau Fracture | Not applicable | Not yet recruiting | Comeback Mobility Inc | 86 | 2026-11-15 | 2026-10-27 |
| SharkScrew ACL RCT ACL Reconstruction with a Biocomposite Screw, ACL Reconstruction using a PEEK Screw, ACL Reconstruction using an Allograft Screw - ACL - Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | Austrian Workers Compensation Board Styria | 33 | 2026-11-01 | 2026-10-05 |
| Magnesium Alloy Scaffold With Controlled Degradation for Periarticular Bone Defects Magnesium Alloy Scaffold, Calcium Sulfate Bone Graft Substitute - Periarticular Bone Defect, Proximal Humerus Fracture | Not applicable | Not yet recruiting | Peking University Third Hospital | 120 | 2026-11-01 | 2026-10-30 |
| Clinical and Biological Outcomes of BioBrace-Augmented ACL Reconstruction BioBrace® Reinforced BioInductive Implant - Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | Yonsei University | 30 | 2026-11-01 | 2026-10-30 |
| Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Recovery Quality in Patients Undergoing Anterior Cruciate Ligament Reconstruction Experimental-Active taVNS, Sham transcutaneous auricular vagus nerve stimulation - Anterior Cruciate Ligament Injuries, Recovery Quality | Not applicable | Not yet recruiting | Peking University Third Hospital | 144 | 2026-10-28 | 2026-10-29 |
| Description of Return to Sport in Amateur Athletes Who Underwent Several Functional Tests (K-STARTS, Vertical Jumps and Soleus Muscle Strength) After Initial ACL Reconstruction Physical tests - ACL - Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 230 | 2026-10-01 | 2026-08-20 |
| Supporting Athletes' Return to Sports After ACL Reconstruction: A Study of a Psychological Readiness Program Unbroken Comeback - Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injuries | Not applicable | Not yet recruiting | Inova Health Care Services | 30 | 2026-10-01 | 2026-10-15 |
| Correlation Study Between the Classification of Arthrogenic Motor Inhibition (AMI) and Clinical Assessment After ACL Rupture Clinical testing - ACL - Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 90 | 2026-10-01 | 2026-08-20 |
| Therapeutic Benefits of a Motor Imaging Protocol Following Anterior Cruciate Ligament Reconstruction Surgery Reconstructive surgery after anterior cruciate ligament rupture, sessions from a physical therapist - Anterior Cruciate Ligament Tear | Not applicable | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 70 | 2026-10-01 | 2026-09-21 |
| Quadriceps Strengthening ACL Reconstruction NMES and BFR, Standard physical therapy - ACL Tear | Not applicable | Recruiting | Stanford University | 20 | 2026-09-29 | 2026-10-15 |
| Effect of Tourniquet Use on the Pivot Shift Test Thigh Tourniquet Inflation - Anterior Cruciate Ligament Injury | Not applicable | Not yet recruiting | Umraniye Education and Research Hospital | 34 | 2026-09-16 | 2026-09-22 |
| Identification of Kinematic Variables Specific of Patellar Tendinopathy in Athletes at Risk The intervention consists of a series of vertical jump tests captured using high-resolution cameras with markerless motion capture technology., The intervention consists of a series of vertical jump tests captured using high-resolution cameras with markerless motion capture technology at 6 months and 12 months - Patellar Tendinitis, Jumper's Knee | Not applicable | Recruiting | University Hospital, Montpellier | 60 | 2026-09-15 | 2026-09-21 |
| Effectiveness of a Digital Prehabilitation Programme Before ACL Reconstruction Digital Prehabilitation Programme, Usual Care - Anterior Cruciate Ligament Injury | Not applicable | Not yet recruiting | Alejandro Caña Pino | 60 | 2026-09-15 | 2026-06-11 |
| Conservative Versus Operative - First Time Patella Dislocations medial patellofemoral reconstruction, Non-operative group - Patella Dislocation | Not applicable | Withdrawn | Columbia University | 2026-09-01 | 2026-09-21 | |
| Assessment of Electromyographic Activity in the Quadriceps and Hamstrings of the Operated Limb Versus the Unaffected Limb in Patients Who Have Undergone ACL Surgery, With and Without Post-operative AMI - an Exploratory Study Electromyography - ACL - Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 40 | 2026-09-01 | 2026-06-22 |
| Anterior Cruciate Ligament (ACL) Reconstruction With Bone Tendon Bone Autograft With Versus Without Internal Bracing ACL reconstruction with BTB autograft with internal brace augmentation (suture tape), ACL reconstruction with BTB autograft without internal brace augmentation (suture tape), Standardized Rehabilitation Protocol - ACL Tear | Not applicable | Withdrawn | Columbia University | 2026-09-01 | 2026-09-21 | |
| Assessment of NEURO-K-STARTS Following Primary Anterior Cruciate Ligament (ACL) Reconstruction NEURO-K-STARTS - ACL - Anterior Cruciate Ligament Rupture | Not applicable | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 144 | 2026-09-01 | 2026-06-22 |
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Anterior Cruciate Ligament Injuries (407) · Osteoarthritis, Knee (29) · Patellar Dislocation (23) · Wounds and Injuries (20) · Iliotibial Band Syndrome (18) · Pain, Postoperative (16) · Athletic Injuries (15) · Tibial Plateau Fractures (15) · Disease (11) · Ankle Injuries (10) · Patella Fracture (8) · Pain (7) · Patellofemoral Pain Syndrome (7) · Muscle Weakness (6)
Leg Injuries (584) · Wounds and Injuries (568) · Musculoskeletal Diseases (79) · Joint Diseases (68) · Pathological Conditions, Signs and Symptoms (52) · Neurologic Manifestations (38) · Signs and Symptoms (38) · Pathologic Processes (36) · Rheumatic Diseases (32) · Arthritis (30) · Fractures, Bone (30) · Osteoarthritis (27) · Joint Dislocations (25) · Knee Fractures (23)
Blood Flow Restriction Therapy (18) · Anterior Cruciate Ligament Reconstruction (14) · Physical Therapy Modalities (12) · Exercise (8) · Ropivacaine (6) · Resistance Training (5) · Control Groups (4) · Plyometric Exercise (4) · Surgical Procedures, Operative (4) · Arthroplasty, Subchondral (3) · Athletic Tape (3) · Bone-Patellar Tendon-Bone Grafting (3) · Bupivacaine (3) · Electric Stimulation (3) · Exercise Therapy (3)
Peking University Third Hospital (22) · GCS Ramsay Santé pour l'Enseignement et la Recherche (10) · Riphah International University (10) · Cairo University (9) · University of Michigan (9) · Mayo Clinic (8) · Stanford University (8) · Chang Gung Memorial Hospital (7) · Chinese University of Hong Kong (7) · Istituto Ortopedico Rizzoli (7) · University of North Carolina, Chapel Hill (7) · Universitas Indonesia (6) · Keller Army Community Hospital (5) · University of Colorado, Denver (5) · Aarhus University Hospital (4)
United States (167) · Turkey (Türkiye) (38) · France (34) · China (27) · Pakistan (24) · Canada (21) · Egypt (21) · Spain (21) · Poland (15) · United Kingdom (15) · Brazil (13) · Belgium (12) · Denmark (12) · Italy (12) · Switzerland (11)
Gregory D Myer, PhD (4) · Robert F LaPrade, MD, PhD (3) · Adam Anz, MD (2) · Adam Weaver, PT, DPT (2) · Brian Pietrosimone, PhD (2) · Chandramouli Krishnan, PT, PhD (2) · Chandramouli Krishnan, PhD (2) · Enejd Veizi, MD (2) · Guillem Gonzalez-Lomas, MD (2) · Hongshi Huang, Doctor (2) · Joseph M Hart, Ph.D. (2) · Juan P Martinez, MD (2) · Konrad Malinowski, MD PhD (2) · Nathan Skelley, MD (2) · Philippe Marchand, MD (2)
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R01AR055563 (2), R21AR082643 (2), 2023 (1), 2025 (1), K01AR082421 (1), K08AR053152 (1), K23AR079056 (1), K23AR084596 (1), P20GM109090 (1), P2CHD086844 (1), P30AR072572 (1), R01AR047910 (1), R01AR074131 (1), R01AR074973 (1), R01AR076153 (1)