7 completed, 3 unknown, 1 recruiting. 11 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 7, Unknown 3, Recruiting 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
Follow Jaw Abnormalities: new trials by email Literature Review of Jaw Abnormalities trials Research Report on Jaw Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Liposomal Bupivacaine Use in Alveolar Bone Graft Patients Liposomal Bupivacaine, Bupivacain, Epinephrine - Cleft Lip and Palate | Phase 3 | Unknown | Kerry O'Rourke | 60 | 2024-04-24 | 2024-07-03 |
| Pharmacological Treatment on the Recovery of Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy Orthognathic Surgery, Melatonin 10 MG Oral Tablet, Hydroxycobalamin - Retrognathism, Prognathism | Phase 2 / Phase 3 | Unknown | Universitat Internacional de Catalunya | 220 | 2022-09-30 | 2022-09-13 |
| A Single Bolus of Dexmedetomidine Versus Normal Saline in Postoperative Agitation Dexmedetomidine, 0.9% saline - Cleft Palate | Phase 3 | Completed | Assiut University | 60 | 2021-06-20 | 2026-05-07 |
| Nebulized Bupivacaine Analgesia for Cleft Palate Repair Bupivacaine Hydrochloride, 0.9% saline - Cleft Palate | Phase 3 | Recruiting | Assiut University | 60 | 2021-06-14 | 2026-09-09 |
| Preventive EXACYL® on Perioperative Bleeding During Orthognathism of Maxillary Surgery Tranexamic Acid, saline solution - Peri-operative Hemorrhage or Hematoma, Surgery | Phase 3 | Completed | University Hospital, Lille | 157 | 2016-01-03 | 2026-04-22 |
| Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate Surgery Levobupivacaine, Bupivacaine - Recovery After Cleft Palate Surgery | Phase 2 / Phase 3 | Completed | Assiut University | 60 | 2016-01-01 | 2017-09-07 |
| Comparative Results of Maxillary Deficiency Treatment by Fixed Tongue Appliance and Fixed Facemask in Growing Patients Fixed Tongue Appliance, Fixed Face Mask - Maxillary Deficiency | Phase 3 | Unknown | Shahid Beheshti University | 20 | 2009-06-01 | 2010-07-27 |
| Comparative Results of Maxillary Deficiency Treatment by Tongue Plate and Facemask in Growing Patients Tongue plate, Facemask - Maxillary Deficiency | Phase 3 | Completed | Shahid Beheshti University of Medical Sciences | 20 | 2007-09-01 | 2008-12-19 |
| Oral Cleft Prevention Program Folic acid: 4 mg versus 0.4 mg per day - Cleft Lip, Cleft Palate | Phase 3 | Completed | University of Iowa | 4000 | 2006-11-01 | 2017-03-31 |
| A Comparison of Bupivacaine and Ketorolac for Postoperative Analgesia After Iliac Crest Bone Harvesting Ketorolac, Bupivacaine, ketorolac + bupivacaine - Postoperative Pain | Phase 3 | Completed | The Hospital for Sick Children | 54 | 2006-05-01 | 2013-08-20 |
| Oral Cleft Prevention Trial in Brazil Folic acid (0.4mg vs. 4.0mg) - Cleft Lip, Cleft Palate | Phase 3 | Completed | NICHD Global Network for Women's and Children's Health | 2200 | 2004-01-01 | 2013-12-17 |
Cleft Palate (7) · Retrognathia (4) · Cleft Lip (3) · Agnosia (1) · Congenital Abnormalities (1) · Hematoma (1) · Pain, Postoperative (1) · Prognathism (1) · Sensation Disorders (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (11) · Craniofacial Abnormalities (11) · Jaw Diseases (11) · Maxillofacial Abnormalities (11) · Musculoskeletal Abnormalities (11) · Musculoskeletal Diseases (11) · Stomatognathic Diseases (11) · Stomatognathic System Abnormalities (11) · Congenital Abnormalities (10) · Mouth Abnormalities (7) · Mouth Diseases (7) · Mandibular Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Lip Diseases (3)
Bupivacaine (4) · Saline Solution (3) · Folic Acid (2) · Cytidine (1) · Dexmedetomidine (1) · Epinephrine (1) · Hydroxocobalamin (1) · Ketorolac (1) · Levobupivacaine (1) · Masks (1) · Melatonin (1) · Orthognathic Surgery (1) · Tablets (1) · Tranexamic Acid (1) · Uridine (1)
Assiut University (3) · Kerry O'Rourke (1) · NICHD Global Network for Women's and Children's Health (1) · Shahid Beheshti University (1) · Shahid Beheshti University of Medical Sciences (1) · The Hospital for Sick Children (1) · Universitat Internacional de Catalunya (1) · University Hospital, Lille (1) · University of Iowa (1)
Egypt (3) · Iran (2) · United States (2) · Brazil (1) · Canada (1) · France (1)
Chad A. Purnell, MD (1) · Elsa Jozefowicz, MD (1) · Jason Hayes, MD (1) · Jeff Murray, M.D. (1) · Jeffrey Murray, MD (1) · Lida Toomarian (1) · Mahkameh Mirkarimi (1) · Mohammad Behnaz (1) · Omar Soliman (1) · Omar Soliman, MD (1) · Pedro Sole, DMD, OMFS (1) · Rahman Showkatbakhsh (1) · Rahman Showkatbakhsh, Professor (1)
PMID 19854614, PMID 21091369, PMID 23181832, PMID 23669628, PMID 24525630, PMID 34465477
2015 (1), U01DE017958 (1)