10 completed, 3 not yet recruiting, 3 recruiting, 3 unknown. 8 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 4.
Follow Ischaemic Stroke: new trials by email Literature Review of Ischaemic Stroke trials Research Report on Ischaemic Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Minocycline in Patients With Acute Ischaemic Stroke Receiving Intravenous Thrombolysis Minocycline Hydrochloride Capsule (50 mg per capsule), Placebo of Minocycline Hydrochloride Capsule (50 mg per capsule, containing 0 mg of minocycline) - Ischaemic Stroke | Phase 3 | Recruiting | Beijing Tiantan Hospital | 934 | 2026-06-05 | 2026-07-01 |
| Cognitive Care Bundle for Ischaemic Stroke : A Pilot Randomised Controlled Trial Cognitive care bundle, Standard Medical Care (SMC) - Ischaemic Stroke, Cognitive Impairment, Mild | Not applicable | Not yet recruiting | National University of Malaysia | 50 | 2026-06-01 | 2026-07-13 |
| Head Cooling in Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy (COOLHEAD-2b) Non-invasive convective head cooling, Standard of Care (SOC) - Stroke, Acute Ischemic Stroke | Not applicable | Not yet recruiting | Auckland City Hospital | 182 | 2026-04-10 | 2026-04-13 |
| Digital Application for Stroke Health StrokeApp, Standard care - Haemorrhagic Stroke, Ischaemic Stroke | Not applicable | Not yet recruiting | VASCage GmbH | 500 | 2026-04-01 | 2026-04-06 |
| Impact of Processing Speed on Motor, Balance, Gait, and Quality of Life in Stroke" Stroke, Ischaemic Stroke | Enrolling by invitation | Istanbul Aydın University | 100 | 2025-09-05 | 2025-09-11 | |
| The RETRAIN Trial Phase 2 Intermittent Pneumatic Compression, geko® T3 - Ischaemic Stroke | Not applicable | Completed | Firstkind Ltd | 53 | 2025-07-01 | 2026-09-15 |
| A Clinical Study to Investigate the Effect of Oral Neflamapimod on Motor Recovery After Acute Ischaemic Stroke Neflamapimod, Placebo - Moderate to Severe Acute Ischaemic Stroke, Ischaemic Stroke | Phase 2 | Active not recruiting | EIP Pharma Inc | 90 | 2025-06-20 | 2026-07-08 |
| Exploratory Study on the Potential Cross-System Effects of BCI-FES Hand Therapy on Dysphagia and Aphasia in Chronic Stroke Patients closed-loop BCI-FES device - Ischaemic Stroke, Hemorrhagic Stroke | Not applicable | Recruiting | VASCage GmbH | 10 | 2025-06-04 | 2025-11-26 |
| Carotid Endarterectomy Versus Stenting in Patients With Acute Stage of Ischemic Stroke. Carotid Artery Stent Placement, carotid endarterectomy - Ischaemic Stroke, Carotid Endarterectomy | Not applicable | Enrolling by invitation | Pirogov Russian National Research Medical University | 50 | 2025-05-21 | 2026-07-29 |
| The RETRAIN Trial (Phase 1) Ischaemic Stroke | Completed | Countess of Chester NHS Foundation Trust | 18 | 2024-10-08 | 2025-03-25 | |
| a Cohort Study of Ischemic Cerebrovascular Disease Intravenous thrombolysis - Ischaemic Stroke | Recruiting | Xiangya Hospital of Central South University | 5000 | 2022-11-01 | 2023-06-28 | |
| SITS-IVT in Patients >80 Years Study Alteplase - Ischaemic Stroke | Completed | Boehringer Ingelheim | 1655 | 2020-05-14 | 2024-07-05 | |
| Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®), Late treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®) - Ischaemic Stroke | Not applicable | Completed | Insel Gruppe AG, University Hospital Bern | 2013 | 2017-11-06 | 2023-07-18 |
| Cerebral Haemodynamics in Stroke Thrombolysis Study (CHIST) intravenous thrombolysis - Ischaemic Stroke | Completed | University of Leicester | 22 | 2016-04-01 | 2020-01-30 | |
| Penumbra and Recanalisation Acute Computed Tomography in Ischaemic Stroke Evaluation control imaging, additional multimodal imaging - Ischaemic Stroke | Not applicable | Unknown | NHS Greater Glasgow and Clyde | 400 | 2015-02-01 | 2018-08-03 |
| Pilot Investigation of Stem Cells in Stroke Phase II Efficacy CTX DP - Ischaemic Stroke, Cerebral Infarction | Phase 2 | Completed | ReNeuron Limited | 23 | 2014-06-01 | 2018-07-23 |
| XILO-FIST, the Effect of Allopurinol on the Brain Heart and Blood Pressure After Stroke Allopurinol, Placebo - Ischaemic Stroke | Phase 4 | Completed | NHS Greater Glasgow and Clyde | 464 | 2014-05-01 | 2021-11-12 |
| Combinational Rehabilitative Therapy and Functional Brain Imaging for Patients Recovering From Motor Stroke Levodopa, Virtual Reality based therapy - Ischaemic Stroke | Phase 3 | Completed | Singapore General Hospital | 9 | 2014-01-01 | 2017-02-10 |
| Atrial Fibrillation Detected by ELR and Holter Recording, a Comparison in Patients With Ischemic Stroke or TIA Stroke, Ischaemic Stroke | Completed | University of Aarhus | 1507 | 2013-06-01 | 2018-05-07 | |
| Diagnosis and Treatment of Minor Ischaemic Stroke According to the Etiology and Pathogenesis Ischaemic Stroke | Unknown | Li Haiyan | 1000 | 2011-06-01 | 2012-08-15 |
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Ischemic Stroke (22) · Stroke (5) · Alzheimer Disease (2) · Atrial Fibrillation (2) · Hemorrhagic Stroke (2) · Angina, Stable (1) · Angina, Unstable (1) · Aortic Aneurysm, Abdominal (1) · Aphasia (1) · Brain Ischemia (1) · Cardiovascular Diseases (1) · Cerebral Infarction (1) · Cognitive Dysfunction (1) · Coronary Disease (1) · Death, Sudden, Cardiac (1)
Brain Diseases (22) · Central Nervous System Diseases (22) · Cerebrovascular Disorders (22) · Nervous System Diseases (22) · Vascular Diseases (22) · Cardiovascular Diseases (21) · Stroke (17) · Pathological Conditions, Signs and Symptoms (6) · Pathologic Processes (5) · Heart Diseases (3) · Mental Disorders (3) · Neurocognitive Disorders (3) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Arrhythmias, Cardiac (2)
Standard of Care (2) · Allopurinol (1) · Dabigatran (1) · Endarterectomy, Carotid (1) · Intermittent Pneumatic Compression Devices (1) · Levodopa (1) · Minocycline (1) · Rivaroxaban (1) · Tissue Plasminogen Activator (1) · VX-745 (1) · apixaban (1) · benserazide, levodopa drug combination (1) · edoxaban (1)
NHS Greater Glasgow and Clyde (2) · VASCage GmbH (2) · Auckland City Hospital (1) · Beijing Tiantan Hospital (1) · Boehringer Ingelheim (1) · Countess of Chester NHS Foundation Trust (1) · EIP Pharma Inc (1) · Firstkind Ltd (1) · Insel Gruppe AG, University Hospital Bern (1) · Istanbul Aydın University (1) · Li Haiyan (1) · National University of Malaysia (1) · Pirogov Russian National Research Medical University (1) · ReNeuron Limited (1) · Singapore General Hospital (1)
United Kingdom (8) · Austria (3) · China (3) · Australia (2) · Belgium (1) · Denmark (1) · Finland (1) · Germany (1) · Greece (1) · India (1) · Ireland (1) · Israel (1) · Italy (1) · Japan (1) · Malaysia (1)
Alan Barber, PhD (1) · Amy G Brodtmann, MBBS PhD (1) · Anxin Wang, PhD (1) · Doug Campbell, MBChB (1) · Harry Hemingway, FRCP (1) · Jesse Dawson (1) · Kausik Chatterjee (1) · Keith Muir, MBChB, MSc, MD, FRCP (1) · Keith W Muir (1) · Michael Knoflach, Assoc.-Prof. (1) · Michala H Sejr, MD (1) · Steven Bell, PhD (1)
PMID 25938519, PMID 26752061, PMID 28331015, PMID 30246149, PMID 30898849, PMID 32772680, PMID 34744989, PMID 35482768, PMID 36792378, PMID 36864979, PMID 37222476, PMID 38753452, PMID 38805207, PMID 39700448, PMID 39874037, PMID 40177749, PMID 40402090, PMID 40785636, PMID 41614485, PMID 42237624
2017 (1)