37 completed, 5 terminated, 4 unknown, 2 not yet recruiting. 37 Not applicable, 8 Phase 2, 6 Phase 4, 2 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psyllium Husk in Pediatric IBS Psyllium Husk, Conventional therapy group - Prebiotic, IBS (Irritable Bowel Syndrome) | Not applicable | Not yet recruiting | Eman ElHaddad | 70 | 2026-10-10 | 2026-10-19 |
| This Study Aims to Evaluate the Safety and Efficacy of Fiber Supplementation on Constipation in Neurologically Impaired Children Using Rectal Wall Thickness Measurement by Ultrasound. Psyllium Husk, Fiber - Constipation, Neurologically Impaired | Not applicable | Active not recruiting | Ain Shams University | 60 | 2025-11-10 | 2026-08-03 |
| Psyllium in Pediatric IBS Psyllium (0.7 g/year of age per day), Psyllium (0.5 g/year of age per day), Placebo - Irritable Bowel Syndrome | Phase 2 | Recruiting | Dr Bruno Chumpitazi, M.D. | 110 | 2025-02-20 | 2026-05-26 |
| NutriPlant - Opportunities for Increasing Consumption of Local Fruits and Vegetables Psyllium, Sauerkraut, Fresh apples - Functional Constipation, Irritable Bowel Syndrome | Not applicable | Not yet recruiting | Institute of Nutrition, Slovenia (Nutris) | 120 | 2025-01-20 | 2025-01-21 |
| Bowel Dysfunction After Low Rectal Resection. An Pilot Study Using Psyllium Husk In Rectal Cancer Patients. Psyllium husk - Low Anterior Resection Syndrome, Quality of Life (QOL) | Not applicable | Completed | Sykehuset Telemark | 24 | 2025-01-01 | 2026-05-11 |
| The Effects of Psyllium Seed on Body Weight and Metabolic Syndrome Indicators in Patients with Schizophrenia psyllium husk - Overweight and Obesity, Metabolic Cardiovascular Syndrome | Not applicable | Completed | Ru-Shin Zhang | 24 | 2024-05-01 | 2025-01-23 |
| Effect of MethylceIlulose or Psyllium on Fermentation of Inulin Assessed Using a Gas Sensing Capsule psyllium, methylcellulose, maltodextrin - Irritable Bowel Syndrome | Not applicable | Completed | University of Nottingham | 20 | 2024-01-01 | 2025-04-01 |
| Synergistic Effects of Natural Oils and Herbal Extracts on Cholesterol Gallstone Dissolution: In Vitro Comparison With Rowachol® Sesame Oil (SO) at 100 mg/mL in dissolving fluid., Extra Virgin Olive Oil (EVOO) at 100 mg/mL in dissolving fluid., 50% Sesame Oil (SO) + 50% Extra Virgin Olive Oil (EVOO). - Cholesterol Gallstone Dissolution | Not applicable | Completed | University of Duhok | 55 | 2023-12-15 | 2025-05-18 |
| The Safety and Efficacy of 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Fecal Incontinence Ramosetron, Psyllium - Fecal Incontinence | Phase 2 / Phase 3 | Unknown | Seoul National University Hospital | 148 | 2023-12-15 | 2023-12-12 |
| Effect of Psyllium (Plantago Ovata) on Digestive Disorders in Familial Amyloidosis Psyllium - Familial Amyloidosis | Not applicable | Withdrawn | Centre Hospitalier Universitaire de Nice | 2023-11-01 | 2023-11-18 | |
| Effect of Methylcellulose or Psyllium on Fermentation of inUlin Assessed USing MRI Psyllium, Methylcellulose, Inulin - Colon, Irritable | Not applicable | Completed | University of Nottingham | 22 | 2023-10-15 | 2024-08-12 |
| Exploring Mechanism of Action of Dietary Fibre on the Gut Microbiota and Metabolites Inulin, Psyllium, Maltodextrin - Psyllium, Inulin | Not applicable | Completed | University of Aberdeen | 40 | 2023-09-07 | 2026-02-12 |
| Effect of Modified Cellulose on Colonic Fermentation of Inulin Psyllium, Methylcellulose, Maltodextrin - Irritable Bowel Syndrome | Not applicable | Completed | University of Nottingham | 30 | 2023-05-09 | 2024-08-15 |
| To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrhea Rifaximin 550 MG, Mebeverine 135 MG, Psyllium Husk - Irritable Bowel Syndrome With Diarrhea | Phase 4 | Completed | Bahria University | 162 | 2023-01-03 | 2023-07-27 |
| Effect of Rate Of Delivery on Colonic Fermentation of inuliN (EON) psyllium, inulin - Irritable Bowel | Not applicable | Completed | University of Nottingham | 17 | 2022-10-28 | 2024-05-01 |
| Effect of Alpha Tocopherol and Psyllium on Lipid Levels in Dyslipidaemia Patients Alpha tocopherol, Combination therapy (Alpha Tocopherol and Psyllium husk), Placebo Control - Dyslipidaemia | Phase 2 | Completed | NUR International University | 60 | 2022-06-15 | 2026-05-27 |
| Reducing Pain and Anxiety Through Dietary Fiber Supplementation in Children With Abdominal Pain Psyllium, Placebo - Functional Abdominal Pain Syndrome | Not applicable | Withdrawn | University of Calgary | 2022-06-01 | 2023-01-26 | |
| Psyllium-enriched Hamburger Meatballs: Effects on Postprandial Lipidemia, Glycemia, Appetite, and Food Intake Psyllium - Nutrition, Healthy, Appetitive Behavior | Not applicable | Completed | Ahmet Murat Günal | 28 | 2022-04-12 | 2024-01-03 |
| Efficacy of Dietary Fiber Supplementation (Soloways) in Patients With Specific Genetic Polymorphisms glucomannan, inulin, and psyllium, placebo - Obesity | Not applicable | Completed | S.LAB (SOLOWAYS) | 108 | 2022-03-02 | 2025-03-27 |
| The Role of Fiber in the Prevention and Treatment of Fecal Incontinence Psyllium - Fecal Incontinence, Irritable Bowel Syndrome With Diarrhea | Not applicable | Completed | Massachusetts General Hospital | 31 | 2021-07-21 | 2026-06-30 |
Showing 20 of 53. Sign in to see all of them.
Irritable Bowel Syndrome (11) · Constipation (9) · Fecal Incontinence (5) · Obesity (4) · Diarrhea (3) · Overweight (3) · Diabetes Mellitus, Type 2 (2) · Dyslipidemias (2) · Hyperlipidemias (2) · Kidney Failure, Chronic (2) · Abdominal Pain (1) · Amyloidosis, Familial (1) · Anxiety Disorders (1) · Appetitive Behavior (1) · Breast Feeding (1)
University of Nottingham (8) · Procter and Gamble (4) · Augusta University (2) · University Medical Centre Ljubljana (2) · Ahmet Murat Günal (1) · Ain Shams University (1) · Bahria University (1) · Centre Hospitalier Universitaire de Nice (1) · Dr Bruno Chumpitazi, M.D. (1) · East Carolina University (1) · Eman ElHaddad (1) · Institute of Nutrition, Slovenia (Nutris) (1) · Massachusetts General Hospital (1) · Mayo Clinic (1) · NUR International University (1)
United States (24) · United Kingdom (9) · Slovenia (3) · Italy (2) · Pakistan (2) · Russia (2) · Canada (1) · Egypt (1) · France (1) · Norway (1) · Spain (1) · Syria (1) · Taiwan (1) · Turkey (Türkiye) (1)
Jernej Pajek, MD, PhD (2) · Alayne D Markland, DO MSc (1) · Anne E Kiltie, Prof (1) · Bobbi Langkamp-Henken, PhD, RD (1) · Bruno Chumpitazi, MD, MPH (1) · Caroline Hoad, PhD (1) · Ching Lam, MB BCh (1) · Clifford Y Wai, MD (1) · Donna Z Bliss, phD (1) · Ece Mutlu, MD (1) · Freny V Mody, MD (1) · Gerald Giesbrecht, PhD (1) · Gianmarco Giorgetti (1)
PMID 34353864, PMID 11820919, PMID 15856043, PMID 18590586, PMID 20686513, PMID 26347971, PMID 26541606, PMID 28821315, PMID 29174952, PMID 29185927, PMID 29634945, PMID 30046155, PMID 31345839, PMID 32421208, PMID 32619212, PMID 32811478, PMID 33982068, PMID 35060943, PMID 36537785, PMID 38398881, PMID 39732438, PMID 41078451, PMID 41194155, PMID 41636227, PMID 42728685
R01NR007756 (1)