10 completed, 4 unknown, 3 terminated, 2 withdrawn. 9 Not applicable, 5 Phase 2, 2 Phase 1, 2 Phase 3.
Follow Enema: new trials by email Literature Review of Enema trials Research Report on Enema
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients Dietary Fiber, Enema Administration, Loperamide Hydrochloride - Low Anterior Resection Syndrome, Rectal Carcinoma | Not applicable | Recruiting | Ohio State University Comprehensive Cancer Center | 80 | 2027-02-15 | 2026-10-06 |
| Tacrolimus Lipid Suspension for Enema in Adult Subjects with Mild to Moderately Active Left-sided/Distal Ulcerative Colitis Who Had an Inadequate Response to the Treatment Tacrolimus Lipid Suspension for enema, Identical Tacrolimus-free Lipid Suspension for Enema - Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate | Phase 2 | Not yet recruiting | Jina Pharmaceuticals Inc. | 150 | 2025-04-01 | 2025-03-12 |
| Bowel Preparation in Minimally Invasive Gynecologic Surgery Bowel Preparation, No bowel preparation - Gynecologic Disease | Not applicable | Withdrawn | Henry Ford Health System | 2025-02-17 | 2026-08-10 | |
| Comparison Study of the Effect of Enema in Anal Surgery enema, no enema - Hemorrhoids, Fistula | Not applicable | Completed | Taipei Medical University Shuang Ho Hospital | 282 | 2022-11-14 | 2023-11-22 |
| Efficacy of Preoperative Enema in the Prevention of Catheter Dysfunction in Peritoneal Dialysis enema - Peritoneal Dialysis Access Failure | Not applicable | Unknown | Air Force Military Medical University, China | 136 | 2022-02-01 | 2022-02-28 |
| RELISTOR's Effects on Opioid-Induced Constipation Relistor Injectable Product, Docusate Calcium, Bisacodyl - OIC | Withdrawn | Methodist Health System | 2021-07-01 | 2026-03-23 | ||
| Bowel Preparation Impact on the Intestinal Microbiome: Oral Preparation vs Enema Oral-agents/Enema - Colorectal Cancer | Not applicable | Completed | Vilnius University | 40 | 2021-04-08 | 2023-11-08 |
| The Necessity of Preoperative Bowel Preparation Enema - Pain, Postoperative, Analgesia | Completed | Taipei Medical University Shuang Ho Hospital | 273 | 2020-03-01 | 2021-09-22 | |
| Griffithsin-based Rectal Microbicide for PREvention of Viral ENTry (PREVENT) Q-Griffithsin (Q-GRFT) enema, Placebo enema - HIV Prevention | Phase 1 | Terminated | Rhonda Brand | 18 | 2019-07-10 | 2023-07-06 |
| Faecal Bacteriotherapy for Ulcerative Colitis Faecal bacterial transplantation, Mesalazine 4G Enema - Ulcerative Colitis | Phase 2 | Completed | Institute for Clinical and Experimental Medicine | 61 | 2017-06-19 | 2021-10-01 |
| MRI in Normal Ileal Pouches, and a Feasibility Study of Dynamic MRI Enema and Defaecating MRI Pouchography MRI with ileal pouch contrast and enema. - Colitis, Ulcerative, Ileal Pouches | Completed | London North West Healthcare NHS Trust | 19 | 2017-05-10 | 2020-02-26 | |
| Does Simethicone Improve Operative Field in Gynecological Operations Simethicone, Enema - Benign Gynecologic Neoplasm | Phase 3 | Unknown | Assiut University | 90 | 2017-01-01 | 2017-01-04 |
| Fecal Microbiota Transplantation as a Treatment for Ulcerative Colitis Colonoscopy, Gastroscopy, Fecal Microbiota - Ulcerative Colitis | Phase 2 | Terminated | Tel-Aviv Sourasky Medical Center | 80 | 2015-07-01 | 2020-06-17 |
| Use of Gastrografin in the Management of Fecal Impaction in Patients With Severe Chronic Constipation Gastrografin, enemas - Fecal Impaction | Phase 2 | Unknown | Jinling Hospital, China | 83 | 2015-04-01 | 2017-08-09 |
| Feasibility Study of Ultrasound Elastography Detecting Prostate Cancer Fleet Enema, Aixplorer® ShearWave Elastography (SWE™), Pre-surgery Ultrasound - Prostate Cancer | Not applicable | Completed | H. Lee Moffitt Cancer Center and Research Institute | 10 | 2013-04-11 | 2017-03-13 |
| Study of the Safety and Tolerability of ALTH12 Versus Mesalamine Enema in Subjects With Left-Sided Ulcerative Colitis mesalamine, ALTH12-1:4, ALTH12-2:4 - Ulcerative Colitis | Phase 1 | Completed | Altheus Therapeutics, Inc. | 9 | 2009-11-01 | 2011-03-29 |
| Will Cleaning the Bowel With an Enema Before Vaginal Prolapse Surgery Prevent Complications? enema - Colon Cleansing | Not applicable | Unknown | Illinois Urogynecology, Ltd. | 310 | 2009-09-01 | 2009-09-22 |
| Enemas Before Elective Cesarean Section enema - Complications After Cesarean Section | Phase 2 | Completed | Wolfson Medical Center | 130 | 2009-01-01 | 2016-04-04 |
| Comparison of Mechanical Bowel Preparation Versus Enema for Candidates to Colorectal Resection for Adenocarcinoma mechanical bowel preparation, enema - Colorectal Cancer | Not applicable | Completed | European Institute of Oncology | 440 | 2007-10-01 | 2018-11-07 |
| Comparison Trial of Enema vs. PEG 3350 for Constipation PEG 3350, milk and molasses enema - Constipation | Not applicable | Terminated | Children's Mercy Hospital Kansas City | 80 | 2006-12-01 | 2020-11-02 |
Showing 20 of 21. Sign in to see all of them.
Colitis, Ulcerative (6) · Colorectal Neoplasms (2) · Fecal Impaction (2) · Agnosia (1) · Colitis (1) · Constipation (1) · Fistula (1) · Genital Diseases, Female (1) · Hemorrhoids (1) · Inflammatory Bowel Diseases (1) · Low Anterior Resection Syndrome (1) · Pain, Postoperative (1) · Patient Satisfaction (1) · Prostatic Neoplasms (1) · Rectal Neoplasms (1)
Taipei Medical University Shuang Ho Hospital (2) · Air Force Military Medical University, China (1) · Altheus Therapeutics, Inc. (1) · Assiut University (1) · Bausch Health Americas, Inc. (1) · Children's Mercy Hospital Kansas City (1) · European Institute of Oncology (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Henry Ford Health System (1) · Illinois Urogynecology, Ltd. (1) · Institute for Clinical and Experimental Medicine (1) · Jina Pharmaceuticals Inc. (1) · Jinling Hospital, China (1) · London North West Healthcare NHS Trust (1) · Methodist Health System (1)
United States (9) · Taiwan (2) · China (1) · Czechia (1) · Egypt (1) · Israel (1) · Italy (1) · Lithuania (1) · United Kingdom (1)
Alessandra C Gasior, DO (1) · Bruno Andreoni, MD (1) · Emilio Bertani, MD (1) · Guy HT Worley, BMBS MRCS (1) · Julio Pow-Sang, M.D. (1) · Ken Ho, MD (1) · Melissa K Miller, MD (1) · Muhammad Aslam, MD (1) · Ning Li, MD (1) · Philip B Miner, M.D. (1) · Richard Meyrat, MD (1) · Roberto Biffi, MD (1) · Samuel Lurie, MD (1) · Susan K Clark, PhD (1) · Tung Cheng Chang, MD, PHD (1)
PMID 22516178, PMID 33251157, PMID 39222391, PMID 40596170
U19AI113182 (1)