9 completed, 3 unknown, 1 terminated. 13 Phase 2, 4 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 13 | Completed 9, Unknown 3, Terminated 1 |
| Phase 1 | 4 | Completed 3, Unknown 1 |
| Phase 3 | 3 | Completed 3 |
Follow Intervertebral Disc Displacement: new trials by email Literature Review of Intervertebral Disc Displacement trials Research Report on Intervertebral Disc Displacement
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fluorescence Imaging With Indocyanine Green(ICG) in Endoscopic Spinal Surgery Indocyanine Green, Fluorescence imaging - Disc Herniation | Phase 1 / Phase 2 | Completed | Zhongnan Hospital | 40 | 2023-04-11 | 2025-12-19 |
| Lidocaine Versus Esmolol for Optimizing Surgical Field Visibility Lidocaine, Esmolol - Lumbar Disc Herniation | Phase 2 | Completed | Zagazig University | 70 | 2020-02-04 | 2020-07-02 |
| Microendoscopic Discectomy Vs Transforaminal Endoscopic Lumbar Discectomy Vs Open Discectomy open discectomy, microendoscopic discectomy, transforaminal endoscopic lumbar discectomy - Lumbar Disc Herniation | Phase 1 / Phase 2 | Unknown | Southeast University, China | 240 | 2015-03-01 | 2015-02-09 |
| The Efficacy and Safety of the 1,414 nm Nd:YAG Laser System for Alleviating Back Pain in a Lumbar Disc Patient 1,414nm Nd:YAG Laser System - Lumbar Herniated Intervertebral Disc | Phase 2 / Phase 3 | Completed | CynosureLutronic | 30 | 2014-10-01 | 2017-03-09 |
| A Study to Evaluate Safety and Exploratory Efficacy of KTP-001 in Subjects With Lumbar Disc Herniation KTP-001 - Lumbar Disc Herniation | Phase 1 / Phase 2 | Completed | Teijin America, Inc. | 24 | 2013-02-01 | 2020-02-11 |
| Safety and Efficacy With NOVOCART® Disc Plus (ADCT) for the Treatment of Degenerative Disc Disease in Lumbar Spine NOVOCART® Disc plus, NOVOCART® Disc basic - Intervertebral Disc Displacement, Intervertebral Disc Degeneration | Phase 1 / Phase 2 | Completed | Tetec AG | 120 | 2012-08-01 | 2021-10-12 |
| Clinical Trial to Evaluate Safety and Efficacy of Hyalospine® in Lumbar Laminectomy or Laminotomy Hyalospine - Degenerative Spinal Stenosis, Disk Herniation | Phase 2 / Phase 3 | Completed | AO Clinical Investigation and Publishing Documentation | 45 | 2009-11-01 | 2012-12-20 |
| Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy Gabapentin , Amitriptyline - Herniated Disc, Intervertebral Disc Displacement | Phase 2 | Unknown | Tabriz University | 120 | 2009-05-01 | 2009-11-17 |
| The Effect of Ozone Therapy for Lumbar Herniated Disc Discectomy/ micro discectomy, Ozone therapy, Oxygen therapy - Lumbar Herniated Disc | Phase 2 | Terminated | Kovacs Foundation | 156 | 2008-12-01 | 2019-08-28 |
| Randomized Controlled Study to Assess the Efficacy of a Dietary Ingredient in Patients With Herniated Lumbar Disc Compression Dietary supplement GVG 2 - Herniated Disc | Phase 2 / Phase 3 | Completed | Tel-Aviv Sourasky Medical Center | 79 | 2006-11-01 | 2008-04-10 |
| Study of REN-1654 in Patients With Sciatica Pain REN-1654 - Sciatica, Herniated Disc | Phase 2 | Unknown | Renovis | 72 | 2003-12-01 | 2005-06-24 |
| Do Benzodiazepines Improve the Outcome of Mechanical Physiotherapy for Lumbar Disk Prolapse benzodiacepine - Pain, Disability | Phase 2 | Completed | University Hospital Tuebingen | 2002-08-01 | 2007-09-21 | |
| Manipulation or Microdiscectomy For Sciatica? A Prospective Randomized Controlled Trial. Spinal Manipulation, Microdiscectomy - Sciatica, Intervertebral Disk Displacement | Phase 2 | Completed | McMorland, Gordon, D.C. | 40 | 2000-01-01 | 2006-12-22 |
Sciatica (2) · Intervertebral Disc Degeneration (1) · Low Back Pain (1) · Muscle Hypotonia (1) · Pain (1) · Paresis (1) · Radiculopathy (1)
Bone Diseases (13) · Hernia (13) · Musculoskeletal Diseases (13) · Pathological Conditions, Anatomical (13) · Pathological Conditions, Signs and Symptoms (13) · Spinal Diseases (13) · Neurologic Manifestations (4) · Signs and Symptoms (4) · Nervous System Diseases (3) · Pain (3) · Mononeuropathies (2) · Neuralgia (2) · Neuromuscular Diseases (2) · Peripheral Nervous System Diseases (2) · Sciatic Neuropathy (2)
Amitriptyline (1) · Diskectomy (1) · Gabapentin (1) · Indocyanine Green (1) · Lidocaine (1) · Manipulation, Spinal (1) · Optical Imaging (1) · Oxygen (1) · esmolol (1)
AO Clinical Investigation and Publishing Documentation (1) · CynosureLutronic (1) · Kovacs Foundation (1) · McMorland, Gordon, D.C. (1) · Renovis (1) · Southeast University, China (1) · Tabriz University (1) · Teijin America, Inc. (1) · Tel-Aviv Sourasky Medical Center (1) · Tetec AG (1) · University Hospital Tuebingen (1) · Zagazig University (1) · Zhongnan Hospital (1)
Germany (2) · United States (2) · Austria (1) · Canada (1) · China (1) · Egypt (1) · Iran (1) · Israel (1) · Netherlands (1) · Spain (1) · Switzerland (1)
Bernardino Clavo, MD (1) · Dawood Aghamohammadi, MD (1) · Francisco M Kovacs, MD, PhD (1) · Francisco Robaina, MD (1) · Gordon McMorland (1) · Hans-Joerg Meisel, Professor (1) · Keung-nyun Kim, Professor (1) · Michael Weller, Prof. (1) · Olfat Ibrahem Amin, M.D (1) · Ory Keynan, M.D. (1) · Paul Pavlov, MD (1) · Payman Vahedi, MD (1) · Randall W Moreadith, MD, PhD (1) · Samuel Dekel, M.D. (1)
PMID 17077737, PMID 19830485, PMID 20447305, PMID 26920137, PMID 40648907