12 completed, 11 recruiting, 4 unknown, 3 terminated. 15 Not applicable, 6 Phase 2, 5 Phase 1, 1 Early Phase 1.
Follow this drug Literature Review of Optical Imaging trials Research Report on Optical Imaging
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fluorescence-Guided Surgical Resection for Reducing Unexpected Positive Margins in Patients With Sarcoma, SarcoSIGHT Trial Electronic Health Record Review, Fluorescence Imaging, Fluorescence-Guided Surgery - High Grade Sarcoma, Sarcoma | Phase 2 | Recruiting | City of Hope Medical Center | 22 | 2026-08-14 | 2026-10-16 |
| Polarization Sensitive Optical Coherence Tomography (PS-OCT) for Retinal Imaging Polarization-Sensitive OFDI - Healthy | Not applicable | Not yet recruiting | Massachusetts General Hospital | 20 | 2026-06-01 | 2025-12-09 |
| High Resolution Imaging OCT Study Autofluorescence Imaging, Infrared reflectance imaging, OCT imaging - Normal Eyes, Age Related Macular Degeneration | Not applicable | Recruiting | Heidelberg Engineering GmbH | 97 | 2026-03-13 | 2026-08-26 |
| Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy Ureteral Stent Placement, No Ureteral Stent, Indocyanine Green with Fluorescence Imaging - Bladder Cancer, Muscle-Invasive Bladder Carcinoma | Not applicable | Recruiting | Thomas Jefferson University | 70 | 2025-12-23 | 2026-02-17 |
| Real-Time Diagnosis of Life-Threatening Necrotizing Soft Tissue Infections (NSTI) Using Indocyanine Green (ICG) Kinetic Modeling Administration of indocyanine green (ICG) and fluorescence imaging - Necrotizing Fascitis | Recruiting | Eric R. Henderson | 420 | 2025-09-26 | 2026-03-19 | |
| The Impact of Artificial Lighting on the Visual Capacity of Patients With Age-Related Macular Degeneration Distant Visual Acuity, Optical Coherence Tomography, Optical Coherence Tomography Angiography - AMD - Age-Related Macular Degeneration | Not yet recruiting | Democritus University of Thrace | 70 | 2025-06-30 | 2025-07-11 | |
| Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer Technetium (99mTc), Indocyanine Green, Sentinel lymph node biopsy - Breast Cancer, Sentinel Lymph Node Biopsy (SLNB) | Not applicable | Recruiting | Isabelle Henskens | 1760 | 2025-04-18 | 2026-06-25 |
| ICAS Screen Based on RIC fundus imaging - Intracranial Atherosclerosis | Recruiting | Xuanwu Hospital, Beijing | 2100 | 2024-09-05 | 2024-10-31 | |
| Fluorescence Imaging of IBD and RA Using Adalimumab-800CW Adalimumab-800CW, Fluorescence Imaging - IBD, Rheumatoid Arthritis | Phase 2 | Recruiting | University Medical Center Groningen | 36 | 2024-08-06 | 2025-08-19 |
| Evaluating the Use of Dual Imaging Techniques for Detection of Disease in Patients With Head and Neck Cancer Panitumumab-IRDye800, Indium In 111 Panitumumab, Single Photon Emission Computed Tomography - Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma | Phase 1 | Recruiting | Vanderbilt-Ingram Cancer Center | 40 | 2023-10-03 | 2025-10-03 |
| Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic Aortic/ cardiac magnetic resonance imaging, Vascular ultrasound, Transorbital Ultrasound - Giant Cell Arteritis, Polymyalgia Rheumatica | Recruiting | University of Bonn | 100 | 2023-09-01 | 2025-04-10 | |
| Fluorescence Imaging With Indocyanine Green(ICG) in Endoscopic Spinal Surgery Indocyanine Green, Fluorescence imaging - Disc Herniation | Phase 1 / Phase 2 | Completed | Zhongnan Hospital | 40 | 2023-04-11 | 2025-12-19 |
| Retrospective Database Review at LTC and SNFs MolecuLight - Non-Healing Ulcer of Skin, Autofluorescence Imaging | Completed | Wound Care Plus, LLC | 193 | 2022-04-20 | 2023-10-05 | |
| Survey of the Facial Bacteriome fluorescence imaging with 405nm light - Understanding Skin Health and the Microbiome, Microbial Colonization | Completed | University Health Network, Toronto | 30 | 2019-11-25 | 2021-03-29 | |
| Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease Swept-Source (SS) OCT Angiography, Spectral-Domain (SD) OCT Angiography, Fundus Imaging - Diabetic Retinopathy, Retinal Vein Occlusion | Not applicable | Recruiting | Johns Hopkins University | 1050 | 2019-10-01 | 2026-06-17 |
| Fluorescence Image Guided Surgery in Cholangiocarcinoma Bevacizumab-IRDye800CW, near infrared (NIR) fluorescence imaging - Hilar Cholangiocarcinoma | Phase 1 / Phase 2 | Unknown | University Medical Center Groningen | 12 | 2019-04-01 | 2021-04-28 |
| China Lung Cancer Screening (CLUS) Study Version 2.0 Low Dose Computed Tomography, artificial intelligence (AI), autofluorescence imaging (AFI) - Lung Neoplasms | Not applicable | Unknown | Shanghai Chest Hospital | 6000 | 2018-08-01 | 2022-06-01 |
| Retinal Microvascularization and Cardiovascular Disease Optical Coherence Tomography angiography, Fundus, cardiac ultrasound scan - High Cardiovascular Risk Patients, Low Cardiovascular Risk Patients | Terminated | Centre Hospitalier Universitaire Dijon | 155 | 2018-03-14 | 2020-05-27 | |
| Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery Fluorescence Imaging, Panitumumab, Panitumumab-IRDye800 - Pancreatic Adenocarcinoma | Phase 1 / Phase 2 | Recruiting | George Poultsides | 27 | 2018-02-07 | 2026-03-17 |
| Prevalence of Age Related Macular Degeneration (ARMD) in Parkinson's Patients and Assesment of the Role of L-DOPA Color retinography, Optical coherence tomography, Fundus autofluorescence imaging - Parkinson Disease, Age Related Macular Degeneration | Completed | Fondation Ophtalmologique Adolphe de Rothschild | 133 | 2018-01-19 | 2019-02-01 |
Showing 20 of 36. Sign in to see all of them.
Macular Degeneration (4) · Breast Neoplasms (3) · Carcinoma, Renal Cell (3) · Mouth Neoplasms (3) · Diabetic Retinopathy (2) · Parkinson Disease (2) · Skin Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Urinary Bladder Neoplasms (2) · Anastomotic Leak (1) · Arthritis, Rheumatoid (1) · Carcinoma, Transitional Cell (1) · Colonic Diseases (1) · Colonic Neoplasms (1) · Colonic Polyps (1)
M.D. Anderson Cancer Center (3) · City of Hope Medical Center (2) · Fondation Ophtalmologique Adolphe de Rothschild (2) · Massachusetts General Hospital (2) · Mayo Clinic (2) · University Health Network, Toronto (2) · University Medical Center Groningen (2) · Centre Hospitalier Universitaire Dijon (1) · Democritus University of Thrace (1) · Eric R. Henderson (1) · George Poultsides (1) · Heidelberg Engineering GmbH (1) · Imperial College London (1) · Intuitive Surgical (1) · Isabelle Henskens (1)
United States (18) · China (3) · France (3) · Netherlands (3) · Canada (2) · Germany (1) · Greece (1) · Hong Kong (1) · Italy (1) · Mexico (1) · United Kingdom (1)
Amir Kashani, MD, MPH (1) · Ann Gillenwater (1) · Ann M Gillenwater (1) · Ann M. Gillenwater, MD (1) · Annemiek Doeksen, MD, PhD (1) · Benjamin Vakoc, Ph.D. (1) · Benjamin Vakoc, PhD (1) · Clayton Lau, MD (1) · Donald W. Northfelt, M.D. (1) · Eben Rosenthal, MD (1) · G. M. van Dam, MD, PhD (1) · George Poultsides (1) · Julian P Teare, MD FRCP (1) · Kristin McNamara, DDS, MS (1)
PMID 32416764, PMID 33647286, PMID 34261044, PMID 36451312, PMID 38580386, PMID 41498537, PMID 42342397
P30CA016672 (2), P01CA084203 (1), P30CA015083 (1), P30CA033572 (1), R01AI184513 (1), R01CA190306 (1), R01CA266233 (1), R01EY030564 (1), R21DE016485 (1)