22 completed, 20 unknown, 11 recruiting, 3 terminated. 59 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 59 | Completed 22, Unknown 20, Recruiting 11, Terminated 3, Not yet recruiting 2, Enrolling by invitation 1 |
Follow Hypothalamic Neoplasms: new trials by email Literature Review of Hypothalamic Neoplasms trials Research Report on Hypothalamic Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Standardized Patient Education in Pituitary Surgery Standardized Pituitary Training - Pituitary Adenoma | Not applicable | Not yet recruiting | Uludag University | 102 | 2026-06-01 | 2026-06-01 |
| DDAVP for Pituitary Adenoma Desmopressin acetate - Cushing's Disease, Pituitary Adenoma | Not applicable | Recruiting | National Institute of Neurological Disorders and Stroke (NINDS) | 22 | 2026-03-09 | 2026-04-09 |
| Clinical Trial of an Anti-Fog Drainage Device for Endoscopic Endonasal Sellar Region Tumor Surgery Anti-fog suction device-a 4 Fr multi-channel silicone catheter - Pituitary Adenoma, Craniopharyngioma | Not applicable | Recruiting | West China Hospital | 20 | 2026-03-01 | 2026-06-30 |
| Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region. Standard-of-care PET/CT, NeuroEXPLORER - Dementia, Movement Disorders | Not applicable | Enrolling by invitation | prof. dr. Koen Van Laere | 1600 | 2025-09-30 | 2026-05-19 |
| NoSeal Trial: Comparing Sealants Versus No Sealant for Preventing CSF Leak After Endonasal Skull Base Surgery Standard multilayer closure without sealant, Fibrin sealant application, Synthetic polyethylene glycol-based sealant - CerebroSpinal Fluid (CSF) Leak | Not applicable | Recruiting | Maria Sklodowska-Curie National Research Institute of Oncology | 225 | 2025-08-15 | 2025-10-14 |
| Proton Versus Photon Radiotherapy in Adults With Primary Brain Tumors Proton Beam Therapy, Photon Radiotherapy - Primary Brain Tumors, Diffuse Glioma | Not applicable | Recruiting | Tata Memorial Centre | 156 | 2025-07-01 | 2025-09-16 |
| KETO-TUMOR: a Study on Brain Tumors and Central Obesity Dietary intervention - Obese Patients, Hypothalamic Neoplasms | Not applicable | Recruiting | Meyer Children's Hospital IRCCS | 30 | 2025-05-08 | 2026-02-09 |
| Surgical and Pharmacological Efficacy of Knosp Grade 0-2 Prolactinoma Transnasal transsphenoidal pituitary lesion resection under neuroendoscopy, Bromocriptin 2.5mg, 2-3 times a day - Pituitary Tumor | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 600 | 2024-10-01 | 2024-08-15 |
| Effect of Foot Bath on Anxiety and Physiological Parameters Warm water foot bath - Pituitary Adenoma, Surgery | Not applicable | Completed | Trakya University | 100 | 2024-09-25 | 2026-04-21 |
| Molecular Pituitary Imaging Using 18F-FET PET 18F-Fluoro-ethyl-tyrosine (FET) PET - Pituitary Adenoma | Not applicable | Recruiting | University of Cambridge | 20 | 2024-09-03 | 2026-01-06 |
| Application of Augmented Reality Neuronavigation in Transnasal Endoscopic Skull Base Surgery Performing endoscopic transnasal skull base surgery with AR-integrated endoscope - Pituitary Neoplasms | Not applicable | Unknown | The First Affiliated Hospital of Xiamen University | 10 | 2024-01-22 | 2024-10-01 |
| Using Polyglycolic Acid Mesh Prevents Cerebrospinal Fluid Leakage polyglycolic acid(Neoveil) - Pituitary Tumor, Cerebrospinal Fluid Leakage | Not applicable | Unknown | National Taiwan University Hospital | 30 | 2023-12-01 | 2024-06-25 |
| Nasal Obstruction Compared by Rhinomanometry and Nasal Inspiratory Peak Flow After Endoscopic Nasal Surgery Nasal patency - rhinomanometry, Nasal patency - nasal inspiratory peak flow - Pituitary Adenoma Invasive, Nasal Obstruction | Not applicable | Unknown | University Hospital Ostrava | 30 | 2023-07-01 | 2023-09-07 |
| Bed Rest on the Effect of CSF Leakage Repair After Transsphenoidal Pituitary Surgery Bed rest - Adenoma Pituitary, CSF Leakage | Not applicable | Unknown | National Taiwan University Hospital | 180 | 2023-03-02 | 2024-04-16 |
| Neurocognition After Radiotherapy in CNS- and Skull-base Tumors Neurocognitive tests: WAIS digit span, HVLT-R, COWAT, MOCA, WAIS digit symbol substitution, TMT A&B, Stroop Color Word Test, MRI, Questionnaires: EORTC QLQ C30 & BN20, STAI, CFQ, BDI-II, BRIEF-A, FACIT-F, PSQI - Cognition, Brain Tumor | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 120 | 2023-02-08 | 2024-05-08 |
| Application Research on Endoscopic Pseudocapsule-Based Resection for Pituitary Adenomas Excision of pituitary tumor outside pseudocapsule - Pituitary Adenoma | Not applicable | Unknown | Affiliated Hospital of Nantong University | 30 | 2022-12-28 | 2023-02-06 |
| Nasoseptal Double Flap Versus Rescue Flap in Endoscopic Transsphenoidal Pituitary Surgery Endoscopic Transsphenoidal pituitary surgery : Double Nasoseptal Flap Technique, Endoscopic Transsphenoidal pituitary surgery : Rescue Flap Technique - Pituitary Adenoma | Not applicable | Completed | Mansoura University | 56 | 2022-12-12 | 2024-08-12 |
| Comparison of Extent of Resection of Pituitary Adenoma Via Transnasal Transsphenoidal Approach Using Endoscope Versus Microscope Endoscopic surgery, Microscopic surgery - Pituitary Adenoma | Not applicable | Completed | Sir Ganga Ram Hospital | 38 | 2022-12-04 | 2026-10-21 |
| Evaluation of the CONVIVO System CONVIVO system, Conventional histologic evaluation - Glioblastoma, Glial Tumor | Not applicable | Recruiting | Dartmouth-Hitchcock Medical Center | 30 | 2022-06-28 | 2026-02-06 |
| Comparative Effectiveness of Different Surgical Approaches for Giant Pituitary Adenomas Two different approaches, Non-combined approach - Surgery, Pituitary Adenoma | Not applicable | Completed | Huashan Hospital | 600 | 2022-01-01 | 2024-10-29 |
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Pituitary Neoplasms (58) · Brain Neoplasms (5) · Meningioma (4) · Pituitary Diseases (4) · Acromegaly (2) · Cerebrospinal Fluid Rhinorrhea (2) · Glioma (2) · Hyponatremia (2) · Neurilemmoma (2) · Prolactinoma (2) · ACTH-Secreting Pituitary Adenoma (1) · Adenoma (1) · Adrenal Insufficiency (1) · Agnosia (1) · Amyotrophic Lateral Sclerosis (1)
Brain Diseases (59) · Central Nervous System Diseases (59) · Central Nervous System Neoplasms (59) · Hypothalamic Diseases (59) · Neoplasms (59) · Neoplasms by Site (59) · Nervous System Diseases (59) · Nervous System Neoplasms (59) · Supratentorial Neoplasms (59) · Endocrine Gland Neoplasms (58) · Endocrine System Diseases (58) · Brain Neoplasms (54) · Pituitary Diseases (54) · Neoplasms by Histologic Type (9)
Desflurane (2) · Hydrocortisone (2) · Propofol (2) · Proton Therapy (2) · Acetaminophen (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Bed Rest (1) · Bromocriptine (1) · Cabergoline (1) · Deamino Arginine Vasopressin (1) · Dexamethasone (1) · Diet Therapy (1) · Early Intervention, Educational (1) · Endoscopic Mucosal Resection (1) · Endoscopy (1)
Huashan Hospital (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · National Taiwan University Hospital (2) · Peking Union Medical College Hospital (2) · Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · St. Joseph's Hospital and Medical Center, Phoenix (2) · Unity Health Toronto (2) · University Hospital Ostrava (2) · Washington University School of Medicine (2) · Affiliated Hospital of Nantong University (1) · Beijing Tiantan Hospital (1) · Cardiff University (1) · Centre Hospitalier Universitaire de Nice (1) · Dartmouth-Hitchcock Medical Center (1) · Emory University (1)
United States (10) · China (9) · France (5) · Canada (4) · South Korea (3) · Taiwan (3) · Turkey (Türkiye) (3) · United Kingdom (3) · Belgium (2) · Czechia (2) · Italy (2) · Egypt (1) · Germany (1) · India (1) · Netherlands (1)
Bing Xing, MD (2) · Prashant Chittiboina, M.D. (2) · Wei Lian, MD (2) · Abel Huang, MD (1) · Ahmad M. Al-Arman (1) · Aled Rees, MB BCh, PhD (1) · Andrej Pala, MD (1) · Andrew Little, MD (1) · Andrew S Little, MD (1) · Anne Klibanski, M.D (1) · Arif Janjua, MD (1) · Bree R Eaton (1) · DongJun Lim, M.D, PhD. (1)
PMID 16509142, PMID 1738293, PMID 17695407, PMID 17862444, PMID 18780796, PMID 19240574, PMID 19970261, PMID 21748460, PMID 22863387, PMID 27864853, PMID 28820308, PMID 30144606, PMID 30649445, PMID 30901746, PMID 31079156, PMID 31377966, PMID 31567997, PMID 31731279, PMID 31857533, PMID 36383383, PMID 38498406, PMID 38918132, PMID 38963694, PMID 39202235, PMID 39852769, PMID 40084913, PMID 41689093, PMID 42770164
2004 (1), P30CA138292 (1)