5 unknown, 4 completed, 1 not yet recruiting, 1 recruiting. 8 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Unknown 5, Completed 2, Not yet recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Cerebrospinal Fluid Rhinorrhea: new trials by email Literature Review of Cerebrospinal Fluid Rhinorrhea trials Research Report on Cerebrospinal Fluid Rhinorrhea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety Evaluation of Absorbable and Moldable Skull Base Support Plates in Extended Endoscopic Endonasal Transsphenoidal Surgery: A Prospective, Randomized, Controlled Study Absorbable and moldable skull base support plate - Sellar Tumor, Endonasal Surgery | Phase 2 | Recruiting | Nanfang Hospital, Southern Medical University | 126 | 2026-04-01 | 2026-04-20 |
| Bed Rest Duration and Outcomes in Endoscopic Skull Base Reconstruction non-bed-rest, 2-day bed-rest, 1-day bed-rest - Skull Base | Not applicable | Not yet recruiting | The Affiliated Hospital of Qingdao University | 316 | 2026-04-01 | 2026-04-07 |
| Using Polyglycolic Acid Mesh Prevents Cerebrospinal Fluid Leakage polyglycolic acid(Neoveil) - Pituitary Tumor, Cerebrospinal Fluid Leakage | Not applicable | Unknown | National Taiwan University Hospital | 30 | 2023-12-01 | 2024-06-25 |
| Bed Rest on the Effect of CSF Leakage Repair After Transsphenoidal Pituitary Surgery Bed rest - Adenoma Pituitary, CSF Leakage | Not applicable | Unknown | National Taiwan University Hospital | 180 | 2023-03-02 | 2024-04-16 |
| Comparison of Duration of CSF Leak in Post Traumatic Patients Managed by Early Lumbar Drain vs Conservative Treatment lumbar drain - CSF Leakage | Not applicable | Unknown | Rawalpindi Medical College | 60 | 2023-02-21 | 2023-03-31 |
| Free Middle Turbinate Flap for Repair of Low Flow Cerebrospinal Fluid Leak free middle turbinate flap, vascularized nasoseptal flap - CSF Leakage | Not applicable | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 100 | 2021-04-01 | 2021-03-05 |
| L-PRF in Cranial Surgery Dural closure with L-PRF, Dural closure with classical fibrin sealants - Cranial Sutures; Closure | Not applicable | Unknown | Universitaire Ziekenhuizen KU Leuven | 350 | 2018-12-01 | 2019-01-22 |
| Endoscopic Repair of Frontal Sinus CSF Leak Endonasal endoscopy - CSF Leakage | Completed | Al-Azhar University | 27 | 2015-05-01 | 2021-08-27 | |
| Chitosan Scaffold for Sellar Floor Repair in Endoscopic Endonasal Transsphenoidal Surgery Implant of bilaminar chitosan scaffold - Csf Leakage | Not applicable | Completed | University of Guadalajara | 1 | 2015-01-01 | 2019-03-14 |
| Performance and Safety of I-020805 in Prevention of Cerebrospinal Fluid (CSF) Leakage Following Elective Craniotomy I-020805 - Cerebrospinal Fluid Leakage | Not applicable | Completed | Kuros Biosurgery AG | 41 | 2011-02-01 | 2016-11-28 |
| Efficacy of Tachosil as Dural Sealant Compared to Standard Treatment Craniotomy supra- or infratentorial, dural closure - Subjects Scheduled for Supra-/Infratentorial Craniotomy | Phase 4 | Completed | University Hospital, Basel, Switzerland | 241 | 2009-10-01 | 2015-09-15 |
Cerebrospinal Fluid Leak (2) · Pituitary Neoplasms (2)
Craniocerebral Trauma (11) · Nervous System Diseases (11) · Neurologic Manifestations (11) · Pathological Conditions, Signs and Symptoms (11) · Rhinorrhea (11) · Signs and Symptoms (11) · Signs and Symptoms, Respiratory (11) · Trauma, Nervous System (11) · Wounds and Injuries (11) · Cerebrospinal Fluid Leak (9) · Brain Diseases (2) · Brain Neoplasms (2) · Central Nervous System Diseases (2) · Central Nervous System Neoplasms (2) · Endocrine Gland Neoplasms (2)
Bed Rest (2)
National Taiwan University Hospital (2) · Al-Azhar University (1) · Kuros Biosurgery AG (1) · Nanfang Hospital, Southern Medical University (1) · Rawalpindi Medical College (1) · The Affiliated Hospital of Qingdao University (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · Universitaire Ziekenhuizen KU Leuven (1) · University Hospital, Basel, Switzerland (1) · University of Guadalajara (1)
China (2) · Taiwan (2) · Belgium (1) · Germany (1) · Hungary (1) · Mexico (1) · Pakistan (1) · Switzerland (1)
Abel Huang, MD (1) · Brenda Vega Ruiz, PhD (1) · Ivan Segura Duran, M.D. (1) · Mariani Luigi, Prof. (1) · Tom Theys, Prof (1) · Virginia Jamieson, MD (1)
PMID 12102194, PMID 15147817, PMID 18395825, PMID 19301105, PMID 21672441, PMID 22120335, PMID 22771458, PMID 22800729, PMID 22823893, PMID 24243224, PMID 24524819, PMID 25036199, PMID 26504833, PMID 26517563, PMID 28117963, PMID 28324618, PMID 28456077, PMID 36959672, PMID 38394657