13 completed, 5 recruiting, 4 unknown, 3 not yet recruiting. 9 Not applicable, 9 Phase 4, 2 Early Phase 1, 1 Phase 2, 1 Phase 3.
Follow Hypotension Drug-Induced: new trials by email Literature Review of Hypotension Drug-Induced trials Research Report on Hypotension Drug-Induced
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alveolar Recruitment Maneuver-Induced Hypotension: A Dynamic Consequence and Intraoperative Indicator of Fluid Responsiveness Alveolar Recruitment Maneuver (ARM), Passive Leg Raising (PLR) Test - Hypotension Drug-Induced, General Anesthesia Using Endotracheal Intubation | Not applicable | Not yet recruiting | University of Health Sciences Balikesir Hospital Eduation and Research | 70 | 2026-07-15 | 2026-08-17 |
| Effect of Lateral Decubitus Position After Spinal Anesthesia on Hemodynamic Stability in High-Risk Geriatric Patients Lateral Decubitus Positioning, Immediate Supine Positioning - Hypotension Drug-Induced, Spinal Aneshtesia | Not applicable | Not yet recruiting | University of Health Sciences Balikesir Hospital Eduation and Research | 70 | 2026-06-01 | 2026-05-19 |
| Hemodynamic Effects of Intravenous Paracetamol in Patients Undergoing Emergency Laparotomy Paracetamol (acetaminophen), Placebo Control - Paracetamol, Hypotension Drug-Induced | Not applicable | Recruiting | Cairo University | 90 | 2026-03-18 | 2026-03-20 |
| Incidence of Pruritus Using Intrathecal Fentanyl Versus Epidural Fentanyl to Initiate Labour Analgesia. Spinal analgesia, Epidural Analgesia - Pruritis, Hypotension Drug-Induced | Not applicable | Not yet recruiting | St. Justine's Hospital | 80 | 2026-01-01 | 2025-11-26 |
| Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal Surgeries Atenolol Succinate Oral Tablet, Metoprolol Succinate Oral Tablet - Hypotension Drug-Induced | Phase 4 | Recruiting | Damanhour Teaching Hospital | 60 | 2025-12-01 | 2026-09-21 |
| Dexmedetomidine vs Propofol in High-Risk ERCP Patients dexmedetomidin, Propofol - Respiratory Depression, Hypoxemia | Not applicable | Completed | Sisli Hamidiye Etfal Training and Research Hospital | 100 | 2025-09-03 | 2026-05-11 |
| Comparison of Pleth Variability Index vs. Diastolic Shock Index for Predicting Hypotension During Anesthesia Induction Pulse variability index measurement, Diastolic shock index - Anesthesia Induced Hypotension, Hypotension Drug-Induced | Completed | Kocaeli City Hospital | 126 | 2024-08-08 | 2025-05-30 | |
| Comparison of Supra vs Infra Inguinal Fascia Iliaca Blocks for Spinal Positioning and Analgesia in Lower Limb Surgery USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, USG GUIDED INFRA-INGUINAL FASCIA ILIACA BLOCK - Post Operative Analgesia, Bradycardia | Phase 2 / Phase 3 | Recruiting | Sahiwal medical college sahiwal | 60 | 2024-05-06 | 2026-01-29 |
| A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia Ephedrine-P, Phenylephrine-P, Norepinephrine-P - Hypotension Drug-Induced | Phase 4 | Recruiting | Dalian Municipal Central Hospital | 180 | 2024-03-05 | 2024-11-06 |
| AKI Risk Factors Analysis After Intentional Hypotensive Anesthesia Nitroglycerin - Acute Kidney Injury (Nontraumatic), Hypotension Drug-Induced | Recruiting | Kaohsiung Medical University Chung-Ho Memorial Hospital | 50 | 2024-03-01 | 2024-02-14 | |
| Hypotension Prediction Index vs Norepinephrine Infusion for Prevention of Spinal Hypotension for Cesarean Delivery Hypotension Prediction Index, Norepinephrine - Hypotension During Surgery, Hypotension Drug-Induced | Phase 4 | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 150 | 2023-09-01 | 2023-08-03 |
| Role of IV Calcium to Prevent Diltiazem-related Hypotension Sodium chloride, 90 mg of calcium, 180 mg Calcium - Atrial Fibrillation, Rapid Ventricular Response | Phase 4 | Completed | Haseki Training and Research Hospital | 217 | 2023-01-01 | 2024-07-11 |
| Diltiazem in the Treatment of Atrial Fibrillation or Atrial Flutter With Rapid Ventricular Rate Calcium pre-treatment, Placebo - Atrial Fibrillation With Rapid Ventricular Response, Hypotension Drug-Induced | Phase 4 | Completed | Wake Forest University Health Sciences | 92 | 2022-11-30 | 2025-11-10 |
| Comparison of Two Different Norepinephrine Bolus Doses for Management of Spinal Anesthesia-Induced Maternal Hypotension Noradrenaline Bitartrate, Bupivacaine Hydrochloride - Spinal Anesthetic Toxicity, Hypotension Drug-Induced | Phase 4 | Completed | Mersin University | 200 | 2022-08-17 | 2023-01-18 |
| Pre-op Fluid Study Crystalloid Solutions - Hypotension Drug-Induced, Anesthesia | Not applicable | Active not recruiting | Medical University of Graz | 550 | 2021-11-01 | 2025-11-21 |
| Is Labetalol More Effective Than Metoprolol for Controlled Hypotensive Anesthesia During Endoscopic Nasal Surgeries? Labetalol Hydrochloride Oral Tablet, Metoprolol Tartrate Oral Tablet - Hypotension Drug-Induced | Phase 4 | Completed | Damanhour Teaching Hospital | 60 | 2021-04-01 | 2023-09-28 |
| Fractional Spinal Anesthesia and Systemic Hemodynamics in Frail Elderly Hip Fracture Patients. Bupivacain - Hip Fractures, Anesthesia | Not applicable | Completed | Sahlgrenska University Hospital | 15 | 2021-01-15 | 2021-11-01 |
| Norepinephrine Addition in Spinal Anesthesia of Caesarean Section Norepinephrine Bolus, Norepinephrine infusion, Normal Saline Flush, 0.9% Injectable Solution - Hypotension Drug-Induced | Not applicable | Completed | Fayoum University Hospital | 300 | 2020-10-16 | 2024-11-26 |
| Maternal Lateral Tilt and Cardiac Output in Caesarean Section Left Lateral Uterine Displacement - Hypotension Drug-Induced | Completed | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 46 | 2020-06-01 | 2021-12-03 | |
| Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair Etomidate, Sevoflurane - Blood Pressure, Hypotension Drug-Induced | Completed | Heidelberg University | 57 | 2019-04-01 | 2021-10-26 |
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Hypotension (26) · Bradycardia (3) · Acute Kidney Injury (1) · Atrial Fibrillation (1) · Cardiac Output, Low (1) · Hip Fractures (1) · Hypoxia (1) · Nausea (1) · Patient Satisfaction (1) · Postoperative Complications (1) · Pruritus (1) · Pulmonary Atelectasis (1) · Respiratory Insufficiency (1) · Urinary Retention (1)
Cardiovascular Diseases (26) · Vascular Diseases (26) · Pathological Conditions, Signs and Symptoms (7) · Heart Diseases (5) · Pathologic Processes (5) · Arrhythmias, Cardiac (4) · Signs and Symptoms (3) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Male Urogenital Diseases (2) · Respiratory Tract Diseases (2) · Urogenital Diseases (2) · Urologic Diseases (2) · Behavior (1) · Femoral Fractures (1)
Bupivacaine (4) · Crystalloid Solutions (2) · Labetalol (2) · Metoprolol (2) · Norepinephrine (2) · Acetaminophen (1) · Analgesia, Epidural (1) · Atenolol (1) · Calcium (1) · Dexmedetomidine (1) · Etomidate (1) · Fentanyl (1) · HES 130-0.4 (1) · Injections, Epidural (1) · Levobupivacaine (1)
Assiut University (2) · Damanhour Teaching Hospital (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · University of Health Sciences Balikesir Hospital Eduation and Research (2) · Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele (1) · Cairo University (1) · Dalian Municipal Central Hospital (1) · Fayoum University Hospital (1) · Haseki Training and Research Hospital (1) · Heidelberg University (1) · Istanbul University (1) · Kaohsiung Medical University Chung-Ho Memorial Hospital (1) · Kocaeli City Hospital (1) · Medical University of Graz (1) · Mersin University (1)
Turkey (Türkiye) (6) · Egypt (4) · Italy (2) · Austria (1) · Canada (1) · China (1) · Colombia (1) · Germany (1) · Indonesia (1) · Pakistan (1) · Sweden (1) · Taiwan (1) · United States (1)
Ahmed M Shaat, MD (2) · Adeel Riaz, MD (1) · Adem Az, M.D. (1) · Adrian E Stephan, MD (1) · Ahmet Yuksek, Associate Proffessor (1) · Andrea Kurz, Prof (1) · Ayse Sencan, Md (1) · Demet Altun (1) · Gaetano A Draisci, MD (1) · Gaetano A Draisci, Prof (1) · Hany M Yassin, M.D. (1) · Hong Fang, MD (1) · Kuang-I Cheng, Phd (1)
PMID 15093843, PMID 1539892, PMID 15758080, PMID 32303180, PMID 35410115, PMID 36442264, PMID 39577214, PMID 7056937