11 unknown, 9 completed, 3 terminated, 2 recruiting. 17 Not applicable, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 17 | Unknown 7, Completed 6, Active not recruiting 1, Recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 4 | 2 | Unknown 2 |
| Phase 3 | 1 | Terminated 1 |
Follow Hypertrophic Obstructive Cardiomyopathy: new trials by email Literature Review of Hypertrophic Obstructive Cardiomyopathy trials Research Report on Hypertrophic Obstructive Cardiomyopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Stereotactic Body Radiotherapy in the Treatment of Hypertrophic Obstructive Cardiomyopathy Stereotactic Body Radiotherapy (SBRT) Treatment, Sham Procedure - Hypertrophic Obstructive Cardiomyopathy, Stereotactic Body Radiotherapy | Not applicable | Unknown | Second Xiangya Hospital of Central South University | 36 | 2023-12-15 | 2023-12-19 |
| The Safety and Influencing Factors of Liwen Procedure in The Treatment of Hypertrophic Cardiomyopathy Percutaneous Intramyocardial Septal Radiofrequency Ablation for hypertrophic obstructive cardiomyopathy (Liwen Procedure) - Hypertrophic Obstructive Cardiomyopathy | Unknown | Xijing Hospital | 486 | 2023-07-21 | 2023-08-22 | |
| Transapical Beating-Heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy: a Multi-Center Study Transapical beating-heart septal myectomy - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Unknown | Xiang Wei | 1000 | 2023-07-01 | 2023-07-24 |
| Quantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Transesophageal Echocardiography Under Provocative Dobutamine Stress Test Pre and post-CPB Drug: Dobutamine Hydrochloride, Post-CPB Drug: Dobutamine Hydrochloride - Hypertrophic Obstructive Cardiomyopathy | Phase 4 | Unknown | University Health Network, Toronto | 60 | 2023-03-01 | 2022-11-08 |
| Transapical Beating-heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy Transapical beating-heart septal myectomy - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Recruiting | Xiang Wei | 1000 | 2022-04-15 | 2024-11-07 |
| Electromechanically Optimised Right Ventricular Pacing In Hypertrophic Cardiomyopathy (EMORI-HCM) AV Delay Optimised RV Pacing - Hypertrophic Cardiomyopathy, Hypertrophic Obstructive Cardiomyopathy | Not applicable | Active not recruiting | Imperial College London | 60 | 2022-03-14 | 2025-05-11 |
| Comparison of Squat-to-Stand Maneuver With Amyl Nitrite, Valsalva, and Exercise Stress Echocardiography in Inducing Latent Left Ventricular Outflow Obstruction in Hypertrophic Cardiomyopathy Squat-to-stand maneuver, Amyl nitrite inhalation, Valsalva - Hypertrophic Cardiomyopathy, Hypertrophic Obstructive Cardiomyopathy | Not applicable | Withdrawn | Mayo Clinic | 2021-11-01 | 2022-01-11 | |
| Esmolol for Myocardial Protection in Hypertrophic Obstructive Cardiomyopathy Esmolol, Placebo - Hypertrophic Obstructive Cardiomyopathy | Phase 4 | Unknown | Meshalkin Research Institute of Pathology of Circulation | 80 | 2021-10-06 | 2021-10-11 |
| First-in-Man Early Feasibility Study for Transcatheter HOCM Septal Ablation TIRA catheter - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Terminated | Tau-MEDICAL Co., Ltd. | 5 | 2021-04-21 | 2025-04-16 |
| Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data Repository Hypertrophic Cardiomyopathy, Hypertrophic Obstructive Cardiomyopathy | Recruiting | Montreal Heart Institute | 2000 | 2021-02-23 | 2026-10-09 | |
| SterEotactic AbLative Radiotherapy in PatiEnts With HypertrophiC ObstrucTive Cardiomyopathy stereotactic ablative radiotherapy - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Completed | Second Xiangya Hospital of Central South University | 5 | 2021-01-12 | 2022-11-30 |
| Hyp Obst Cardiomyopathy The Septal myectom - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Unknown | Assiut University | 98 | 2020-05-01 | 2020-04-01 |
| Edge-to-edge Mitral Valve Repair in the Surgical Treatment for Hypertrophic Cardiomyopathy mitral valve repair by edge-to-edge technique, Septal myectomy - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 40 | 2020-03-12 | 2020-07-21 |
| Risk Factors of Postoperative Complications in HCM Patients Hypertrophic Obstructive Cardiomyopathy | Unknown | Xijing Hospital | 120 | 2020-02-01 | 2020-02-19 | |
| Advancing Understanding of Transportation Options Driving Decision Aid, Older Drivers Website - Diabetic Retinopathy, Macular Degeneration | Not applicable | Completed | University of Colorado, Denver | 529 | 2019-12-12 | 2025-02-21 |
| Mitral Regurgitation in Hypertrophic Obstructive Cardiomyopathy: Fix it in a Simple, Effective and Durable Way! Septal myectomy and mitral valve repair with edge-to-edge technique - Hypertrophic Obstructive Cardiomyopathy, Mitral Regurgitation | Completed | Michele De Bonis | 26 | 2019-10-05 | 2023-05-09 | |
| A Cardiac Disease Quality of Life Study QOL Survey - Hypertrophic Obstructive Cardiomyopathy, Thoracic Aortic Dilatation | Terminated | The Cleveland Clinic | 380 | 2019-08-26 | 2026-09-17 | |
| The Clinical Research of the Safety and Effectiveness Evaluation for Using Echocardiography-guided Liwen RF Radiofrequency Ablation System to Treat Hypertrophic Obstructive Cardiomyopathy Echocardiography-guided Radiofrequency ablation for Hypertrophic obstructive Cardiomyopathy (HOCM). - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Unknown | Xijing Hospital | 150 | 2019-07-30 | 2021-01-15 |
| The Effect of TASH in Patients With HOCM alcohol septal ablation - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Completed | Steen Hvitfeldt Poulsen | 24 | 2019-05-29 | 2023-11-18 |
| Association Between Microvascular Resistance and Outcomes in Patients With Obstructive Hypertrophic Cardiomyopathy Microvascular Dysfunction, Hypertrophic Obstructive Cardiomyopathy | Completed | China National Center for Cardiovascular Diseases | 340 | 2017-01-01 | 2023-01-13 |
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Cardiomyopathy, Hypertrophic (27) · Mitral Valve Insufficiency (3) · Cardiomyopathies (2) · Postoperative Complications (2) · Acute Coronary Syndrome (1) · Arthritis (1) · Bites and Stings (1) · Brain Injuries (1) · Cardiomyopathy, Hypertrophic, Familial (1) · Death, Sudden, Cardiac (1) · Dementia (1) · Diabetes Mellitus, Type 1 (1) · Diabetic Retinopathy (1) · Dizziness (1) · Glaucoma (1)
Aortic Stenosis, Subvalvular (27) · Aortic Valve Disease (27) · Aortic Valve Stenosis (27) · Cardiovascular Diseases (27) · Heart Diseases (27) · Heart Valve Diseases (27) · Cardiomyopathies (25) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Chemically-Induced Disorders (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Genetic Diseases, Inborn (2) · Vascular Diseases (2) · Wounds and Injuries (2) · Apnea (1)
Aspirin (1) · Ethanol (1) · Lead (1) · Mitral Valve Annuloplasty (1) · Radiosurgery (1) · Therapeutics (1) · Valsalva Maneuver (1) · bis(p-chlorophenyl)acetic acid (1) · esmolol (1)
Xijing Hospital (5) · Meshalkin Research Institute of Pathology of Circulation (4) · Second Xiangya Hospital of Central South University (2) · Xiang Wei (2) · Assiut University (1) · China National Center for Cardiovascular Diseases (1) · Chinese Academy of Medical Sciences, Fuwai Hospital (1) · Imperial College London (1) · Mayo Clinic (1) · Michele De Bonis (1) · Montreal Heart Institute (1) · Ottawa Heart Institute Research Corporation (1) · Steen Hvitfeldt Poulsen (1) · Tau-MEDICAL Co., Ltd. (1) · The Cleveland Clinic (1)
China (10) · Russia (5) · Canada (2) · United States (2) · Denmark (1) · Italy (1) · South Korea (1) · United Kingdom (1)
Aleksandr V Bogachev-Prokophiev, PhD (2) · Alexander V. Bogachev-Prokophiev, MD, PhD (1) · Aun-Yeong Chong, MD, MRCP (1) · Azad Mashari, MD (1) · Elena Pavlyukova, MD, PhD (1) · Hailong Dong, MD, Ph.D (1) · Jacobo Moreno Garijo, MD (1) · Jeffrey Geske, MD (1) · Lihong Ma, MD (1) · Marian E Betz, MD, MPH (1) · Milind Desai, M. D. (1) · Rafik Tadros, Dr. (1) · Seung-Whan Lee, MD, PhD (1) · Steen Hvitfeldt Poulsen, DMSc (1) · Xiang Wei, M.D. (1)
PMID 16539843, PMID 20659762, PMID 23713888, PMID 28575282, PMID 31642911, PMID 33628143, PMID 33680117, PMID 33934709, PMID 35441700, PMID 36270787, PMID 37165977, PMID 37503357, PMID 37558369, PMID 38238666, PMID 38388470, PMID 38519968, PMID 39626218, PMID 39767669, PMID 40315478, PMID 40833749, PMID 40892619
R01AG059613 (1)