45 completed, 18 unknown, 5 not yet recruiting, 5 recruiting. 39 Not applicable, 9 Phase 1, 8 Phase 2, 4 Phase 4, 3 Phase 3.
Follow Lead: new trials by email Literature Review of Lead trials Research Report on Lead
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Identification of Neuromusculoskeletal Variables Associated With Injury Risk and Performance in High School Athletes. Pre-season strength and conditioning program - Athletic Injuries | Not yet recruiting | The University of Texas Medical Branch, Galveston | 250 | 2028-08-01 | 2026-02-10 | |
| Study of XNW5004 Tablets in Advanced Prostate Cancer XNW5004 1200 mg BID in Combination with Abiraterone plus Prednisone, XNW5004 1200 mg BID in Combination with Docetaxel plus Prednisone, XNW5004 800 mg or 1200 mg (1:1 randomization), PO, BID; Abiraterone 1000 mg PO, taken on an empty stomach at least 1 hour before and at least 2 hours after a meal, QD; plus Prednisone 5 mg PO BID - Advanced Prostate Cancer | Phase 2 | Not yet recruiting | Evopoint Biosciences Inc. | 242 | 2026-07-13 | 2026-07-28 |
| Biomarkers of Response to SEEG Thermocoagulation Quality of life questionnaires (QOLIE, EFIQUACEE for children), psychiatric questionnaires (NDDIE, GAD-7, PCL-5) at Visit 1 (V1), V5, V6 and V7, Resting state SEEG recording 30min before and 30 min after RFTC, Blood sample at Visit 1 (V1), V2, V4 and V5 - Drug Resistant Epilepsy | Not applicable | Recruiting | Assistance Publique Hopitaux De Marseille | 45 | 2026-06-19 | 2026-06-26 |
| Implementation Guided by aN Iterative, adapTivE Strategy - Induction of Labor BASE, LEAD, TEAM - Birth; Induced | Not applicable | Active not recruiting | University of Michigan | 64 | 2026-06-12 | 2026-07-10 |
| Evaluation of Occlusal Contact Distribution in Digitally Fabricated Implant-Retained Fixed Partial Dentures in Mandibular Kennedy Class II Patients Following Artificial Intelligence Bite Optimization: A Quasi-Experimental Study After, Before - Partially Edentulous Mandible | Not applicable | Not yet recruiting | Cairo University | 15 | 2026-06-01 | 2026-06-18 |
| Navigator-Assisted Hypofractionation (NAVAH) on Radiation Therapy Completion in Breast Cancer and Prostate Cancer Pre & Post Surveys, Opt Out of Questionnaire - Breast Cancer, Prostate Cancer | Recruiting | University of Oklahoma | 420 | 2025-10-16 | 2025-12-17 | |
| Drug-drug Interaction Study of Omeprazole and Bemnifosbuvir/Ruzasvir Treatment A-Bemnifosbuvir/Ruzasvir FDC administered fasting, Treatment B-Omeprazole 20 mg dose administered fasting, Treatment C-Bemnifosbuvir/Ruzasvir FDC administered simultaneously with 20 mg dose of Omeprazole fasting - Healthy Volunteer Study | Phase 1 | Completed | Atea Pharmaceuticals, Inc. | 20 | 2025-05-09 | 2025-08-29 |
| Impact of a Perioperative Physical Exercise and Respiratory Physiotherapy Program on the Patient Undergoing Bariatric Surgery Pre- and post-operative physical exercise programme, Pre- and post-operative respiratory physiotherapy - Bariatric Surgery and Physical Activity, Obesity/Therapy | Not applicable | Recruiting | Fundacin Biomedica Galicia Sur | 132 | 2025-05-07 | 2026-10-13 |
| Pelvic Floor Dysfunction and Quality of Life in Patient Undergoing Gynecological Surgery Pre and Post op pelvic floor muscle training, Only post op pelvic floor muscle training, Routine medical care - Pelvic Floor Dysfunction | Not applicable | Completed | Riphah International University | 48 | 2025-04-25 | 2025-12-01 |
| Comparing Back Extensor and Core Stability Training in Kyphosis Back Extensor Strengthening Exercises, Core Stability Exercises - Thoracic Kyphosis | Not applicable | Completed | Riphah International University | 40 | 2025-04-15 | 2026-02-25 |
| Mental Health Treatment to Improve Father Depression and Child Outcomes in Kenya LEAD (Learn, Engage, Act, Dedicate) - Father-Child Relations, Depression | Not applicable | Completed | Florida International University | 114 | 2025-04-15 | 2026-10-29 |
| Interactive Oral Health Educational Program for Children With Intellectual Disability and Their Caregivers A Before and After study, before and after study - Intellectual Disability, Caregiver Burden | Not yet recruiting | Cairo University | 30 | 2025-02-14 | 2025-02-20 | |
| Effect of Cognitive Empathy Training on Dementia Caregivers Cognitive Empathy Training, Control Condition, Pre and post intervention blood spot collection - Caregivers of People Living With Dementia, Dementia | Not applicable | Recruiting | Emory University | 118 | 2025-02-13 | 2026-08-18 |
| Preoperative Partial Breast Reirradiation and Repeat Breast-conserving Surgery in Patients With Recurrent Breast Cancer: the REPEAT Trial ablative single-dose PBI - Recurrent Breast Carcinoma, Ipsilateral Recurrence | Phase 2 | Recruiting | Amsterdam UMC, location VUmc | 25 | 2025-01-01 | 2026-07-16 |
| Role Of Non-Specific Effects in The Treatment of Depression With Esketamine Pre and Post Treatment Presentations - Depressive Episode | Not applicable | Terminated | Yale University | 1 | 2024-07-13 | 2026-01-14 |
| PROSpECT-PRIOR-2-CHEMO: PRIOR Dental Intervention Before Chemo to Reduce Chemotherapy Complications PRIOR [Proactive Intensive Oral Review & Treatment] - Oncology, Periodontitis | Not applicable | Not yet recruiting | University of Leeds | 60 | 2024-07-01 | 2024-06-10 |
| Developing School Health Champions to Increase Health Literacy Both in School Adolescents and Community People Through Providing Health Education by the School Nurses in Bangladesh: Community-based Pre- and Post-experimental Design pre and post test (health educational intervention) - Health Literacy | Not applicable | Completed | Hiroshima University | 138 | 2024-02-24 | 2026-02-19 |
| Prednisone Plus IVIg vs. Prednisone for ITP During Pregnancy Prednisone, IVIg - Immune Thrombocytopenia | Phase 2 | Unknown | Peking University People's Hospital | 100 | 2023-10-19 | 2024-08-29 |
| Comparison of the Effects of Sacrospinous Fixation and V-notes Lateral Suspension Operations pre and post operative POP-Q results, pre and post operative PİSQ-12 results - Genital Prolapse, Unspecified | Not applicable | Completed | Gaziosmanpasa Research and Education Hospital | 70 | 2023-09-01 | 2025-11-25 |
| Perioperative Energy Expenditure in Major Liver Resection Pre- and postoperative assessment - Cancer, Liver Diseases | Unknown | Academisch Ziekenhuis Maastricht | 20 | 2023-05-01 | 2024-08-05 |
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Breast Neoplasms (6) · Brain Neoplasms (3) · HIV Infections (3) · Diabetes Mellitus, Type 1 (2) · Lung Neoplasms (2) · Motor Activity (2) · Neoplasms (2) · Pain (2) · Pneumonia (2) · Acquired Immunodeficiency Syndrome (1) · Adenocarcinoma (1) · Agnosia (1) · Alcohol Drinking (1) · Anxiety Disorders (1) · Athletic Injuries (1)
Dong-A ST Co., Ltd. (4) · George Washington University (3) · Memorial Sloan Kettering Cancer Center (3) · Assistance Publique - Hôpitaux de Paris (2) · Cairo University (2) · GlaxoSmithKline (2) · Riphah International University (2) · The Leeds Teaching Hospitals NHS Trust (2) · Aalborg University (1) · Academisch Ziekenhuis Maastricht (1) · Alexandria University (1) · Amsterdam UMC, location VUmc (1) · Assistance Publique Hopitaux De Marseille (1) · Atea Pharmaceuticals, Inc. (1) · Barretos Cancer Hospital (1)
United States (26) · France (8) · South Korea (6) · Netherlands (5) · United Kingdom (5) · Canada (4) · China (4) · Germany (4) · Brazil (3) · India (3) · Italy (3) · Pakistan (3) · Bangladesh (2) · Belgium (2) · Egypt (2)
Ahmed M ElMenshawy, Lecturer (1) · Ajay Gupta, MD, PhD (1) · Aleksander Goch, Prof. (1) · Alexandre Jacinto, MD (1) · Ali Giusto, PhD (1) · Andrei Holodny, MD (1) · Andrew Peterson, MD (1) · Arnaud Robitaille, MD, FRCPC (1) · Aurimery G Chermont (1) · Auro del Giglio, phD (1) · Ayesha Sadiq, MSPT (OMPT) (1)
PMID 17132678, PMID 19948613, PMID 20117459, PMID 20730056, PMID 20730057, PMID 22965962, PMID 22971152, PMID 23538593, PMID 24428927, PMID 25079400, PMID 25910919, PMID 27248436, PMID 28484424, PMID 32079919, PMID 32748394, PMID 32755891, PMID 33059633, PMID 33114652, PMID 33407753, PMID 33603701, PMID 34319575, PMID 34333603, PMID 36352294, PMID 36751400, PMID 36813015, PMID 36854456, PMID 37312017, PMID 38985220, PMID 40063847, PMID 40296638, PMID 40570024, PMID 40681188, PMID 40685160, PMID 40978500, PMID 42329680, PMID 42814235
2016 (1), 2UL1TR001863-06 (1), R01AG087216 (1), R34MH081760 (1), R34MH112445 (1)