93 completed. 93 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 93 | Completed 93 |
Follow Hyperglycemia: new trials by email Literature Review of Hyperglycemia trials Research Report on Hyperglycemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes. Metformin, Dulaglutide, Semaglutide 1.0 mg - Diabetes Mellitus Type 2 | Phase 4 | Completed | Fundación para la Investigación del Hospital Clínico de Valencia | 92 | 2025-05-26 | 2026-09-04 |
| Metformin Use in Patients Undergoing Total Joint Replacement Surgery Metformin, Placebo - Hyperglycemia | Phase 4 | Completed | Oregon Health and Science University | 40 | 2024-06-27 | 2025-12-05 |
| Effects of Dapagliflozin on Inflammatory Factorslevel and Prognosis in Type 2 Diabetes With Acute Myocardial Infarction Dapagliflozin 10mg/Tab, control group - Myocardial Infarction, Diabete Type 2 | Phase 4 | Completed | Qingdao Central Hospital | 143 | 2023-05-08 | 2026-01-05 |
| Insulin for Hyperglycemia in Stroke Trial Analog Insulin, Human insulin - Hyperglycemia, Stroke, Acute | Phase 4 | Completed | National Institute of Neurosciences and Hospital, Dhaka | 452 | 2021-04-05 | 2021-12-06 |
| GLP-1 Therapy: The Role of IL-6 Signaling and Adipose Tissue Remodeling in Metabolic Response Cyanocobalamin, Dulaglutide - Glucose Intolerance, Overweight and Obesity | Phase 4 | Completed | The University of Texas Health Science Center, Houston | 23 | 2020-05-15 | 2024-12-05 |
| Once Weekly GLP-1 in Persons With Spinal Cord Injury Semaglutide 1MG Injection [Ozempic], No Intervention - Spinal Cord Injuries, Insulin Resistance | Phase 4 | Completed | James J. Peters Veterans Affairs Medical Center | 5 | 2018-10-16 | 2023-03-14 |
| Effect of Ciprofloxacin Versus Levofloxacin on QTc-interval and Dysglycemia Ciprofloxacin 400 MG/200 ML Intravenous Solution, Levofloxacin 750 MG - QTc Prolongation, Hyperglycemia, Hypoglycemia | Phase 4 | Completed | Beni-Suef University | 200 | 2018-06-01 | 2020-07-02 |
| Peripheral Nerve Blocks for Above-the-knee Amputations Peripheral nerve block, Intravenous Sedatives, Lateral femoral cutaneous nerve blocks - Peripheral Vascular Diseases, Hyperglycaemia (Diabetic) | Phase 4 | Completed | University of Florida | 30 | 2018-02-09 | 2026-01-08 |
| Metformin and Its Impact on the Substances Associated With NO Production in Prediabetes Patients. Metformin - PreDiabetes, Impaired Fasting Glucose (IFG) | Phase 4 | Completed | Wroclaw Medical University | 47 | 2017-10-20 | 2022-05-27 |
| Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan Metformin and Glimepiride (Low Dosage), Metformin and Vildagliptin (Low Dosage), Metformin and Insulin Glargine U100 (Low Dosage) - Diabetes Mellitus, Type 2 | Phase 4 | Completed | University of Jordan | 687 | 2017-02-14 | 2020-02-11 |
| Effect of Dapagliflozin on Insulin Secretion and Insulin Sensitivity in Patients With Prediabetes Dapagliflozin, Placebo - Prediabetes, Impaired Fasting Glucose | Phase 4 | Completed | University of Guadalajara | 24 | 2016-10-01 | 2020-10-28 |
| Effect of Linagliptin + Metformin on Patients Who do Not Achieve Normoglucemia With Metformine Linagliptin / Metformin Oral Tablet, Metformin - Prediabetic State, Impaired Glucose Tolerance | Phase 4 | Completed | Universidad de Guanajuato | 31 | 2016-09-01 | 2019-09-13 |
| Sitagliptin in Non-Diabetic Patients Undergoing General Surgery Sitagliptin, Placebo, Supplemental insulin (insulin lispro) - Hyperglycemia | Phase 4 | Completed | Emory University | 80 | 2016-06-01 | 2018-06-27 |
| Improving Beta Cell Function in Mexican American Women With Prediabetes Liraglutide, Weight loss - Pre-Diabetes | Phase 4 | Completed | Ohio State University | 360 | 2016-05-01 | 2019-08-28 |
| Comparison of 2 Hyperglycemia-correction Scales in Hospitalized Patients Insulin, insulin - Diabete Type 2, Hyperglycemia | Phase 4 | Completed | Hospital Universitario Clinica San Rafael | 116 | 2016-01-01 | 2023-03-03 |
| Remifentanil and Glycemic Response in Cardiac Surgery Remifentanil, Fentanyl - Heart Diseases, Hyperglycemia | Phase 4 | Completed | Kathirvel Subramaniam | 116 | 2016-01-01 | 2020-04-21 |
| Sitagliptin for Hyperglycemia in Patients With T2DM Undergoing Cardiac Surgery Sitagliptin, Placebo, Regular Human Insulin - Hyperglycemia | Phase 4 | Completed | Emory University | 202 | 2016-01-01 | 2019-12-23 |
| Benefits of Insulin Supplementation for Correction of Hyperglycemia in Patients With Type 2 Diabetes Insulin glargine, Insulin aspart, Supplemental insulin aspart - Diabetes Mellitus, Type 2 | Phase 4 | Completed | Emory University | 226 | 2015-10-01 | 2023-09-28 |
| Glucose Control During Glucocorticoid Therapy in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Dapagliflozin, Sliding scale insulin - Hyperglycemia Steroid-induced | Phase 4 | Completed | Slotervaart Hospital | 46 | 2015-02-01 | 2018-05-22 |
| Hyperglycemia and Effects of Daily 100 mg Versus 200 mg of Hydrocortisone Therapy in Patients With Septic Shock Hydrocortisone - Hyperglycemia | Phase 4 | Completed | Srinakharinwirot University | 80 | 2014-10-01 | 2017-10-06 |
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Glucose Intolerance (37) · Diabetes Mellitus, Type 2 (30) · Diabetes Mellitus (22) · Insulin Resistance (19) · Hypoglycemia (10) · Obesity (8) · Hypertension (7) · Prediabetic State (5) · Diabetes Mellitus, Type 1 (4) · Metabolic Syndrome (4) · Dyslipidemias (3) · Myocardial Infarction (3) · Overweight (3) · Schizophrenia (3)
Metabolic Diseases (93) · Nutritional and Metabolic Diseases (93) · Glucose Metabolism Disorders (92) · Endocrine System Diseases (54) · Diabetes Mellitus (31) · Hyperinsulinism (21) · Pathological Conditions, Signs and Symptoms (21) · Cardiovascular Diseases (12) · Signs and Symptoms (12) · Vascular Diseases (12) · Nutrition Disorders (11) · Body Weight (10) · Overnutrition (10) · Pathologic Processes (10)
Insulin Glargine (16) · Insulin (15) · Metformin (12) · Sitagliptin Phosphate (9) · Exenatide (7) · Insulin Aspart (6) · Insulin Lispro (6) · Pioglitazone (5) · dapagliflozin (4) · Acarbose (3) · Insulin Detemir (3) · Insulin, Isophane (3) · Linagliptin (3) · Liraglutide (3) · Vildagliptin (3)
Emory University (6) · Karolinska Institutet (3) · Novartis Pharmaceuticals (3) · Baylor College of Medicine (2) · Carl T. Hayden VA Medical Center (2) · Cook County Health (2) · Medical University of Graz (2) · Nathan Kline Institute for Psychiatric Research (2) · Northwestern University (2) · Ohio State University (2) · The University of Texas Health Science Center at San Antonio (2) · University of Florida (2) · University of Oslo School of Pharmacy (2) · University of Pittsburgh (2) · Beni-Suef University (1)
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Guillermo Umpierrez, MD (5) · Mark E Molitch, M.D. (2) · Robert C Smith, MD PhD (2) · Aaron S. Kelly, Ph.D. (1) · Absalon D Gutierrez, MD (1) · Adrian Vella, M.D. (1) · Adriana Franzese, Dr (1) · Adrienne M Lynn, FRACP (1) · Ahmed A Elberry, professor (1) · Amalia Gastaldelli, PhD (1) · Ambika Babu, MD,MS (1) · Andrew R Hoffman, MD (1)
PMID 17513708, PMID 23435159, PMID 37526194, PMID 11889147, PMID 15793249, PMID 15823767, PMID 16123520, PMID 17229660, PMID 19156705, PMID 19158048, PMID 19190104, PMID 19318384, PMID 19336639, PMID 19454394, PMID 19719706, PMID 19814947, PMID 20039889, PMID 20200309, PMID 20409690, PMID 20457512, PMID 20536957, PMID 20557887, PMID 20923490, PMID 21228246, PMID 21861845, PMID 22040840, PMID 22223765, PMID 22232134, PMID 22456695, PMID 22475524, PMID 22681705, PMID 22688337, PMID 22871230, PMID 22992074, PMID 23186969, PMID 23200554, PMID 23877988, PMID 24035165, PMID 25168125, PMID 25466315, PMID 25835492, PMID 25838513, PMID 26116695, PMID 26197707, PMID 26336609, PMID 26492541, PMID 26620049, PMID 26656289, PMID 26786573, PMID 27405306
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