3 not yet recruiting, 3 recruiting, 1 unknown. 2 Phase 3, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Not yet recruiting 2 |
| Phase 2 | 1 | Not yet recruiting 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow HIE - Hypoxic - Ischemic Encephalopathy: new trials by email Literature Review of HIE - Hypoxic - Ischemic Encephalopathy trials Research Report on HIE - Hypoxic - Ischemic Encephalopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Stem Cells to Treat Perinatal Brain Injury to Combat Cerebral Palsy MSC, marrow, Placebo - Perinatal Arterial Ischemic Stroke, Perinatal Asphyxia | Phase 2 / Phase 3 | Not yet recruiting | UMC Utrecht | 162 | 2027-04-01 | 2026-09-21 |
| COMPARISON OF OUTCOME OF HYPOXIC ISCHEMIC ENCEPHLOPATHY MANAGED WITH COMBINATION OF MAGNESIUM SULPHATE AND MELATONIN VERSUS MAGNESIUM SULPHATE ALONE MgSO4 (seizure prevention), Melatonin , Mgso4 - HIE - Hypoxic - Ischemic Encephalopathy | Phase 3 | Not yet recruiting | University of Child Health Sciences and Children's Hospital, Lahore | 80 | 2026-07-01 | 2026-06-17 |
| Treatment of Seizures in Neonate With HIE Phenobarbital, Levetiracetam - Neonatal Seizures, HIE - Hypoxic - Ischemic Encephalopathy | Phase 4 | Not yet recruiting | Mansoura University | 66 | 2026-01-01 | 2025-12-16 |
| Speech of Kids After Neonatal Encephalopathy HIE - Hypoxic - Ischemic Encephalopathy, Language Delay | Recruiting | Semmelweis University | 93 | 2025-04-01 | 2025-08-22 | |
| Assessing Intellectual and Motor Outcomes in High-risk Infants Cerebral Palsy, Cerebral Palsy (CP) | Recruiting | University College Cork | 600 | 2025-03-21 | 2026-05-13 | |
| Biomarkers Study in Infants With Prior Neonatal Brain Injury HIE - Hypoxic - Ischemic Encephalopathy, Perinatal Anoxic-ischemic Brain Injury | Recruiting | University of Wisconsin, Madison | 100 | 2023-03-13 | 2026-02-17 | |
| Effect of Targeted Temperature Management on Cerebral Autoregulation in Patients With Neurocritical Diseases Ischemic Stroke, Subarachnoid Hemorrhage, Aneurysmal | Unknown | Xiangya Hospital of Central South University | 100 | 2021-01-22 | 2021-01-28 |
Hypoxia-Ischemia, Brain (2) · Premature Birth (2) · Attention Deficit Disorder with Hyperactivity (1) · Autistic Disorder (1) · Brain Injuries, Traumatic (1) · Cerebral Hemorrhage (1) · Cerebral Palsy (1) · Cognitive Dysfunction (1) · Developmental Disabilities (1) · Intellectual Disability (1) · Ischemic Stroke (1) · Language Development Disorders (1) · Sepsis (1) · Specific Language Disorder (1) · Subarachnoid Hemorrhage (1)
Nervous System Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Brain Diseases (3) · Cardiovascular Diseases (3) · Central Nervous System Diseases (3) · Cerebrovascular Disorders (3) · Signs and Symptoms (3) · Vascular Diseases (3) · Brain Ischemia (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Hypoxia (2) · Hypoxia, Brain (2) · Mental Disorders (2) · Neurodevelopmental Disorders (2) · Obstetric Labor Complications (2)
Levetiracetam (1) · Magnesium Sulfate (1) · Melatonin (1) · Phenobarbital (1)
Mansoura University (1) · Semmelweis University (1) · UMC Utrecht (1) · University College Cork (1) · University of Child Health Sciences and Children's Hospital, Lahore (1) · University of Wisconsin, Madison (1) · Xiangya Hospital of Central South University (1)
China (1) · Egypt (1) · Hungary (1) · Ireland (1) · United States (1)
Deirdre M Murray (1) · Lina Zhang, PhD (1) · Melisa Carrasco McCaul, MD, PhD (1) · Moetaza Soliman, Associate Professor (1) · Nada Abdelfattah, Associate Professor (1)
PMID 15791116, PMID 32385134, PMID 34124790, PMID 34867732, PMID 35311411, PMID 35673948, PMID 36401982, PMID 36578326, PMID 36823477, PMID 42575547, PMID 987769
2025 (1)