3 completed. 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 3 | Completed 3 |
Follow Geriatric Depression: new trials by email Literature Review of Geriatric Depression trials Research Report on Geriatric Depression
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketamine for Older Adults Pilot Ketamine - Treatment Resistant Depression, Refractory Depression | Phase 4 | Completed | Washington University School of Medicine | 25 | 2020-10-22 | 2023-02-14 |
| RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT) Aripiprazole Augmentation, Bupropion Augmentation, Switch to bupropion - Depression, Dementia | Phase 4 | Completed | Centre for Addiction and Mental Health | 87 | 2019-08-01 | 2024-11-25 |
| Optimizing Outcomes of Treatment-Resistant Depression in Older Adults Aripiprazole Augmentation, Bupropion Augmentation, Switch to bupropion - Treatment Resistant Depression, Major Depressive Disorder | Phase 4 | Completed | Washington University School of Medicine | 742 | 2017-02-24 | 2024-10-03 |
Depressive Disorder, Treatment-Resistant (3) · Depressive Disorder, Major (2) · Cognitive Dysfunction (1) · Dementia (1) · Depression (1)
Depressive Disorder (3) · Mental Disorders (3) · Mood Disorders (3) · Behavior (1) · Behavioral Symptoms (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Cognition Disorders (1) · Nervous System Diseases (1) · Neurocognitive Disorders (1)
Aripiprazole (2) · Bupropion (2) · Lithium Carbonate (2) · Nortriptyline (2) · Ketamine (1)
Washington University School of Medicine (2) · Centre for Addiction and Mental Health (1)
Canada (3) · United States (3)
Eric Lenze, MD (2) · Aristotle Voineskos, MD (1)
PMID 36867173, PMID 37392089, PMID 38822571, PMID 41237789
R01MH114966 (1), R01MH114970 (1), R01MH114980 (1), R01MH114981 (1)