38 completed. 38 Phase 3, 9 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 38 | Completed 38 |
| Phase 2 | 9 | Completed 9 |
Follow Foot Ulcer: new trials by email Literature Review of Foot Ulcer trials Research Report on Foot Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Restoring Tissue and Evaluating Novel Treatments for Efficacy in Wounds Lavior Diabetic Wound Gel, Smith & Nephew Solosite Gel Hydrogel Wound Dressing - Diabetic Foot Ulcer | Phase 2 / Phase 3 | Completed | Lavior Pharma Inc. | 75 | 2022-12-15 | 2024-10-08 |
| Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Wagner Grade 2 Foot Ulcers. ALLO-ASC-DFU, Vehicle Sheet - Diabetic Foot Ulcer | Phase 3 | Completed | Anterogen Co., Ltd. | 104 | 2020-07-14 | 2025-09-22 |
| Phase 3 Study to Evaluate the Safety and Efficacy of Galnobax® in Treating Diabetic Foot Ulcers Esmolol Hydrochloride, Only Standard of Care, Vehicle Gel - Diabetic Foot Ulcer | Phase 3 | Completed | Novalead Pharma Private Limited | 176 | 2018-12-26 | 2023-09-22 |
| Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Foot Ulcers. ALLO-ASC-DFU, Vehicle sheet - Diabetic Foot Ulcer | Phase 3 | Completed | Anterogen Co., Ltd. | 150 | 2018-06-27 | 2023-08-25 |
| Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers Dermacell, Integra - Diabetic Foot Ulcer, Deep Diabetic Foot Ulcer | Phase 2 / Phase 3 | Completed | Baylor College of Medicine | 34 | 2018-04-02 | 2023-07-07 |
| Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot Ulcers Gentamicin Collagen sponge, Placebo - Foot Ulcer, Diabetic, Infection | Phase 3 | Completed | Innocoll | 524 | 2015-06-01 | 2021-09-29 |
| Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers Chitosan, Isosorbide dinitrate, Placebo - Diabetic Foot Ulcers | Phase 3 | Completed | University of Guadalajara | 68 | 2015-06-01 | 2021-01-12 |
| Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot Ulcers Gentamicin collagen sponge, Placebo - Foot Ulcer, Diabetic, Infection | Phase 3 | Completed | Innocoll | 612 | 2015-05-01 | 2021-08-25 |
| Clinical Efficacy of Platelet Gel From Cord Blood for the Treatment of Diabetic Foot Ulcers Allogeneic cord blood platelet gel-CBPG, Standard Local Medications-SLM - Diabetic Foot Ulcers | Phase 3 | Completed | Centro Nazionale Sangue | 50 | 2015-01-01 | 2017-07-21 |
| A Phase 3 Clinical Trial to Assess the Effectiveness of BioChaperone PDGF-BB In the Treatment of Chronic Diabetic Foot Ulcer BioChaperone PDGF-BB, Standard of Care - Diabetic Foot Ulcer | Phase 3 | Completed | Adocia | 252 | 2014-12-01 | 2017-06-29 |
| Effect of Topic Pirfenidone in Diabetic Ulcers Pirfenidone, Debridement - Diabetic Foot Ulcers | Phase 3 | Completed | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | 36 | 2013-10-01 | 2016-02-15 |
| Efficacy & Safety of Pedyphar Ointment in Diabetic Foot Ulcer Treatment Pedyphar Ointment, Panthenol - Diabetic Foot Ulcer | Phase 3 | Completed | European Egyptian Pharmaceutical Industries | 80 | 2013-04-01 | 2015-03-05 |
| Medico-economical Assessment of Telemedicine During Chronic Diabetes-related Foot Wound Management telemedicine, conventional - Diabetes, Diabetic Foot Ulcer | Phase 2 / Phase 3 | Completed | University Hospital, Grenoble | 14 | 2013-03-01 | 2018-05-29 |
| Evaluate the Efficacy and Safety of ON101 Cream for the Treatment of Chronic Diabetic Foot Ulcers ON101 Cream, Aquacel® Hydrofiber® dressing - Diabetic Foot | Phase 3 | Completed | Oneness Biotech Co., Ltd. | 236 | 2012-11-23 | 2021-04-14 |
| VA MERIT: A Comparative Efficacy Study: Treatment of Non-Healing Diabetic SECONDARY dressing gauze and tape, debridement, irrigation, Dermagraft - Diabetic Foot Ulcer | Phase 3 | Completed | VA Office of Research and Development | 120 | 2011-10-01 | 2019-09-17 |
| Ertapenem Sodium (MK-0826) Versus Piperacillin/Tazobactam Sodium for the Treatment of Diabetic Foot Infections in Chinese Adults (MK-0826-061) Ertapenem sodium, Piperacillin/tazobactam sodium, Piperacillin/tazobactam-matching placebo - Infection; Diabetic Foot | Phase 3 | Completed | Merck Sharp & Dohme LLC | 565 | 2011-09-02 | 2018-08-27 |
| Evaluation of CureXcell® in Treating Lower Extremity Chronic Ulcers in Adults With Diabetes CureXcell®, Sham injection - Lower Extremity Chronic Ulcers in Diabetics | Phase 3 | Completed | Macrocure Ltd. | 285 | 2011-08-01 | 2015-12-07 |
| Off- Loading Shoe to Improve Healing and Prevention of Recurrence of Neuropathic Diabetic Plantar Foot Ulcers SANIDIAB, BAROUK - Diabetes Mellitus, Diabetic Neuropathic Foot Ulcer | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 33 | 2011-06-01 | 2013-11-14 |
| The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Northern Europe The TRANS-North Study Trafermin 0.01% spray - Diabetic Foot Ulcer of Neuropathic Origin | Phase 3 | Completed | Olympus Biotech Corporation | 207 | 2010-12-01 | 2014-08-05 |
| The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Southern Europe The TRANS-South Study Trafermin 0.01% spray - Diabetic Foot Ulcer of Neuropathic Origin | Phase 3 | Completed | Olympus Biotech Corporation | 201 | 2010-11-01 | 2014-08-05 |
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Diabetic Foot (38) · Diabetes Mellitus (10) · Ulcer (8) · Infections (3) · Wounds and Injuries (3) · Diabetes Complications (2) · Osteomyelitis (2) · Abscess (1) · Bacterial Infections (1) · Cellulitis (1) · Diabetic Neuropathies (1) · Patient Compliance (1) · Soft Tissue Infections (1) · Wound Infection (1)
Cardiovascular Diseases (38) · Diabetic Angiopathies (38) · Endocrine System Diseases (38) · Leg Ulcer (38) · Skin Diseases (38) · Skin Ulcer (38) · Skin and Connective Tissue Diseases (38) · Vascular Diseases (38) · Diabetic Neuropathies (37) · Diabetes Complications (36) · Diabetes Mellitus (28) · Glucose Metabolism Disorders (10) · Metabolic Diseases (10) · Nutritional and Metabolic Diseases (10)
Standard of Care (3) · Dalteparin (2) · Debridement (2) · Ertapenem (2) · Ofloxacin (2) · Piperacillin (2) · Tazobactam (2) · pexiganan (2) · salicylhydroxamic acid (2) · trafermin (2) · Acetylcysteine (1) · Amoxicillin (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Chitosan (1) · Congresses as Topic (1)
Abeona Therapeutics, Inc (2) · Anterogen Co., Ltd. (2) · Innocoll (2) · Olympus Biotech Corporation (2) · Organogenesis (2) · Pfizer (2) · Abbott Nutrition (1) · Adocia (1) · Assistance Publique - Hôpitaux de Paris (1) · Bayer (1) · Baylor College of Medicine (1) · Centro Nazionale Sangue (1) · Chinese University of Hong Kong (1) · Diabetica Solutions Inc. (1) · European Egyptian Pharmaceutical Industries (1)
United States (16) · Italy (9) · United Kingdom (8) · Germany (7) · Poland (7) · Spain (7) · Belgium (6) · Austria (5) · Denmark (5) · France (5) · Hungary (5) · Russia (5) · Sweden (5) · Canada (4) · Czechia (4)
Jean-Charles Kerihuel, MD (2) · Nigel Jones (2) · Paul Litka, MD (2) · Anne Voss, PhD, RD (1) · Arturo Orduz, MD (1) · Arun Bal, MD (1) · Ashu Rastogi, MD (1) · BaekKyu Kim, MD. Ph D (1) · C. Mauli Agrawal, Ph.D. (1) · Carlos A Calderon, PhD (1) · Changsik Park, MD. Ph D. (1) · Christian F Rueda-Clausen, MD (1)
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