7 completed, 2 withdrawn, 1 recruiting. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 7, Withdrawn 2, Recruiting 1 |
Follow Filariasis: new trials by email Literature Review of Filariasis trials Research Report on Filariasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases Moxidectin, Ivermectin - Onchocerciasis, Ascaris Lumbricoides Infection | Phase 4 | Recruiting | Kirby Institute | 52000 | 2025-08-04 | 2025-11-21 |
| Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin Administration of Albendazole on Day 1, Administration of Ivermectin on Day 1, Administration of Azithromycin on Day 1 - Trachoma, Lymphatic Filariases | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 13511 | 2021-12-01 | 2022-08-19 |
| Loiasis Cross-reactive Antigenemia and Treatment-related Adverse Events Ivermectin - Loiasis | Phase 4 | Completed | Washington University School of Medicine | 41 | 2021-07-30 | 2022-09-29 |
| Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy Ivermectin - Ivermectin, Onchocerciasis | Phase 4 | Completed | Robert Colebunders | 91 | 2017-10-01 | 2019-01-07 |
| Twice Yearly Treatment for the Control of LF 400 μg/kg Ivermectin + 400 mg Albendazole - Lymphatic Filariasis, Helminth Infection | Phase 4 | Completed | Noguchi Memorial Institute for Medical Research | 1462 | 2017-05-19 | 2020-02-26 |
| Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis Praziquantel - Schistosomiasis | Phase 4 | Withdrawn | National Institute of Allergy and Infectious Diseases (NIAID) | 2016-04-06 | 2019-12-17 | |
| Safety Study of Combined Azithromycin, Ivermectin and Albendazole for Trachoma and Lymphatic Filariasis azithromycin, ivermectin, albendazole - Trachoma, Lymphatic Filariasis | Phase 4 | Withdrawn | Emory University | 2014-02-01 | 2014-05-22 | |
| Post-treatment Effects of Ivermectin (IVM) or Diethylcarbamazine (DEC) in Loiasis Diethylcarbamazine, Ivermectin - Loiasis | Phase 4 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 155 | 2012-04-01 | 2016-11-09 |
| Alternate Chemotherapy Regimens for the Clearance of W.Bancrofti Infection Diethylcarbamazine, Albendazole, Doxycycline - Filarial; Infestation | Phase 4 | Completed | Indian Council of Medical Research | 146 | 2009-02-01 | 2013-12-09 |
| Impact of Albendazole -Ivermectin on Wuchereria Bancrofti in Mali ''albendazole'' and ''ivermectin'' - Lymphatic Filariasis | Phase 4 | Completed | Centre d'Appui à la lutte contre la Maladie | 1139 | 2001-05-01 | 2016-05-27 |
Elephantiasis, Filarial (5) · Loiasis (2) · Onchocerciasis (2) · Trachoma (2) · Coinfection (1) · Epilepsy (1) · Hookworm Infections (1) · Neglected Diseases (1) · Parasitic Diseases (1) · Scabies (1) · Schistosomiasis (1) · Trematode Infections (1) · Trichuriasis (1)
Helminthiasis (10) · Infections (10) · Nematode Infections (10) · Secernentea Infections (10) · Spirurida Infections (10) · Parasitic Diseases (9) · Vector Borne Diseases (6) · Hemic and Lymphatic Diseases (5) · Lymphatic Diseases (5) · Lymphedema (5) · Mosquito-Borne Diseases (5) · Bacterial Infections (2) · Bacterial Infections and Mycoses (2) · Chlamydia Infections (2)
Ivermectin (7) · Albendazole (4) · Diethylcarbamazine (2) · Albumins (1) · Azithromycin (1) · Doxycycline (1) · Praziquantel (1) · moxidectin (1)
National Institute of Allergy and Infectious Diseases (NIAID) (2) · Centre d'Appui à la lutte contre la Maladie (1) · Emory University (1) · Indian Council of Medical Research (1) · Kirby Institute (1) · London School of Hygiene and Tropical Medicine (1) · Noguchi Memorial Institute for Medical Research (1) · Robert Colebunders (1) · Washington University School of Medicine (1)
Cameroon (2) · Angola (1) · Democratic Republic of the Congo (1) · Ethiopia (1) · Ghana (1) · India (1) · Mozambique (1)
Amy D Klion, M.D. (2) · Dziedzom K de Souza, PhD (1) · Huub C Gelderblom, MD, PhD, MPH (1) · Lourduraj J De Britto, M.D (1) · Michel Mandro, MD (1) · Ricardo Thompson, PhD (1) · Susana V Nery, PhD (1)
PMID 23981378, PMID 26691247, PMID 28329346, PMID 28855148, PMID 28969715, PMID 31314757, PMID 31923177, PMID 37152362