10 completed, 3 recruiting, 1 not yet recruiting. 14 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 14 | Completed 10, Recruiting 3, Not yet recruiting 1 |
| Phase 2 | 6 | Completed 4, Not yet recruiting 1, Recruiting 1 |
Follow Essential Tremor: new trials by email Literature Review of Essential Tremor trials Research Report on Essential Tremor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Motor and Non-Motor Effects of Low-Intensity Focused Ultrasound (LIFU) as a Neuromodulation Tool in Essential Tremor Low-Intensity Focused Ultrasound (LIFU) - NeuroFUS PRO - Essential Tremor (ET) | Phase 1 / Phase 2 | Not yet recruiting | University of Sao Paulo General Hospital | 20 | 2026-03-17 | 2026-03-19 |
| Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor Deep Brain Stimulation - Tremor, Essential Tremor | Phase 1 | Recruiting | The Cleveland Clinic | 12 | 2026-01-15 | 2026-07-10 |
| Dual-Site Transcranial Magnetic Stimulation of the Supplementary Motor Area and Cerebellum for the Treatment of Essential Tremor. Dual-site repetitive transcranial magnetic stimulation (rTMS) of the supplementary motor area and cerebellum, Transcranial Magnetic Stimulation Sham - Essential Tremor | Phase 1 / Phase 2 | Recruiting | São Paulo State University | 36 | 2026-01-15 | 2026-01-21 |
| Coordinated Reset Deep Brain Stimulation for Essential Tremor Deep brain stimulation - Essential Tremor, Upper Extremity Essential Tremor | Phase 1 | Recruiting | University of Minnesota | 23 | 2023-09-11 | 2026-10-20 |
| Trial of Cannabis for Essential Tremor CBD/THC, Placebo oral capsule - Essential Tremor | Phase 1 / Phase 2 | Completed | University of California, San Diego | 7 | 2019-01-22 | 2022-10-13 |
| Effects of Octanoic Acid for Treatment of Essential Voice Tremor Octanoic acid, Inactive capsule - Essential Voice Tremor, Vocal Tremor | Phase 1 / Phase 2 | Completed | Syracuse University | 17 | 2013-07-01 | 2018-08-20 |
| Magnetic Resonance (MR) Guided Functional Ultrasound-Neurosurgery for Movement Disorders Non-invasive intervention with focused ultrasound (ExAblate 4000) - Essential Tremor, Dystonia | Phase 1 | Completed | University Children's Hospital, Zurich | 10 | 2012-11-01 | 2014-10-09 |
| Octanoic Acid for Essential Tremor Octanoic Acid - Essential Tremor | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 18 | 2011-10-28 | 2019-12-16 |
| ExAblate Transcranial MR Guided Focused Ultrasound in the Treatment of Essential Tremor ExAblate Transcranial MRgFUS System - Essential Tremor | Phase 1 | Completed | InSightec | 10 | 2011-02-01 | 2016-03-08 |
| ExAblate Transcranial MR Guided Focused Ultrasound in the Treatment of Essential Tremor ExAblate Transcranial MRgFUS System - Essential Tremor | Phase 1 | Completed | InSightec | 15 | 2011-01-01 | 2013-08-26 |
| Double-Blind, Placebo Controlled Pilot Study of Octanoic Acid in Essential Tremor Octanoic Acid, Placebo - Essential Tremor | Phase 1 / Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 29 | 2009-02-01 | 2012-12-27 |
| Efficacy of Levetiracetam in Essential Tremor levetiracetam, placebo - Essential Tremor | Phase 1 / Phase 2 | Completed | Southern California Institute for Research and Education | 10 | 2005-01-01 | 2009-04-17 |
| 1-Octanol to Treat Essential Tremor 1-Octanol - Essential Tremor | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 42 | 2001-05-01 | 2008-03-04 |
| 1-Octanol to Treat Essential Tremor 1-Octanol - Essential Tremor | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 12 | 2000-01-01 | 2008-03-04 |
Tremor (6) · Movement Disorders (3) · Dysphonia (1) · Dystonia (1) · Neuralgia (1) · Parkinson Disease (1) · Voice Disorders (1)
Central Nervous System Diseases (14) · Nervous System Diseases (14) · Movement Disorders (11) · Dyskinesias (7) · Neurologic Manifestations (7) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Basal Ganglia Diseases (1) · Brain Diseases (1) · Laryngeal Diseases (1) · Neurodegenerative Diseases (1) · Neuromuscular Diseases (1) · Otorhinolaryngologic Diseases (1) · Pain (1) · Parkinsonian Disorders (1)
octanoic acid (3) · 1-Octanol (2) · Deep Brain Stimulation (2) · Cannabidiol (1) · Dronabinol (1) · Levetiracetam (1) · Transcranial Magnetic Stimulation (1) · nabiximols (1)
National Institute of Neurological Disorders and Stroke (NINDS) (4) · InSightec (2) · Southern California Institute for Research and Education (1) · Syracuse University (1) · São Paulo State University (1) · The Cleveland Clinic (1) · University Children's Hospital, Zurich (1) · University of California, San Diego (1) · University of Minnesota (1) · University of Sao Paulo General Hospital (1)
United States (10) · Brazil (1) · South Korea (1) · Switzerland (1)
Fatta Nahab, MD (1) · Jin Woo Chang, Prof. (1) · Jing Wang, PhD (1) · Mark Hallett, M.D. (1) · Rubens Gisbert Cury (1) · Soren Y Lowell, PhD (1) · Steven S Schreiber, MD (1)
PMID 14718713, PMID 15210907, PMID 21594724, PMID 22454323, PMID 23408867, PMID 23944301, PMID 26927672
R03DC012429 (1)