11 completed. 11 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 11 |
| Phase 2 | 4 | Completed 4 |
Follow Endothelial Dysfunction: new trials by email Literature Review of Endothelial Dysfunction trials Research Report on Endothelial Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Endothelial Protection in Post COVID-19 Patients With Sulodexide Sulodexide - Post COVID-19, Endothelial Dysfunction | Phase 3 | Completed | Centro Medico del Noroeste | 206 | 2023-06-01 | 2024-08-09 |
| Adrecizumab in Cardiogenic Shock Adrecizumab, Placebo - Cardiogenic Shock, Endothelial Dysfunction | Phase 2 / Phase 3 | Completed | Dr. med. Mahir Karakas | 150 | 2019-04-04 | 2021-10-08 |
| Effect of Febuxostat on Endothelial Dysfunction in Hemodialysis Patients. Febuxostat, Placebo - Endothelial Dysfunction, Endstage Renal Disease | Phase 2 / Phase 3 | Completed | Ain Shams University | 57 | 2016-08-01 | 2018-01-02 |
| Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air Oxygen, Air - Hyperbaric, Diving Medicine | Phase 2 / Phase 3 | Completed | Göteborg University | 48 | 2015-05-01 | 2022-05-27 |
| Effect of Eplerenone on Endothelial Function in Metabolic Syndrome Eplerenone - Metabolic Syndrome, Endothelial Dysfunction | Phase 3 | Completed | University of Erlangen-Nürnberg Medical School | 42 | 2010-09-01 | 2013-04-17 |
| Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Progenitor Cells and Coronary Atherosclerosis in Humans darapladib, placebo - Endothelial Dysfunction | Phase 3 | Completed | Mayo Clinic | 70 | 2010-02-04 | 2017-04-18 |
| Vildagliptin and Endothelium-dependent Vasodilatation vildagliptin + acarbose, acarbose + vildagliptin - Type 2 Diabetes, Endothelial Dysfunction | Phase 3 | Completed | Radboud University Medical Center | 16 | 2010-01-01 | 2010-11-05 |
| Effects of Exercise Training and AGE-crosslink Breaker on Cardiovascular Structure and Function Alt-711, Physical exercise training - Cardiovascular Disease, Aging | Phase 2 / Phase 3 | Completed | Radboud University Medical Center | 48 | 2008-11-01 | 2013-09-09 |
| Prevention of Type 2 Diabetes Mellitus by L-Arginine in Patients With Metabolic Syndrome L-arginine, Placebo - Metabolic Syndrome, Impaired Glucose Tolerance | Phase 3 | Completed | IRCCS San Raffaele | 142 | 2005-12-01 | 2009-06-10 |
| Acute Effects of Sildenafil on Endothelial Function in People With Diabetes Sildenafil - Type 2 Diabetes Mellitus, Endothelial Dysfunction | Phase 3 | Completed | Ruhr University of Bochum | 40 | 2001-08-01 | 2007-09-11 |
| Correlation of Endothelial Function and Early Coronary Artery Disease in Humans Atrasentan, atrasentan - Endothelial Dysfunction | Phase 3 | Completed | Mayo Clinic | 200 | 2001-07-01 | 2010-04-30 |
Diabetes Mellitus, Type 2 (3) · Metabolic Syndrome (2) · Cardiovascular Diseases (1) · Coronary Vasospasm (1) · Decompression Sickness (1) · Glucose Intolerance (1) · Inflammation (1) · Insulin Resistance (1) · Motor Activity (1) · Shock, Cardiogenic (1) · Thrombosis (1)
Glucose Metabolism Disorders (4) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Cardiovascular Diseases (3) · Diabetes Mellitus (3) · Endocrine System Diseases (3) · Vascular Diseases (3) · Heart Diseases (2) · Hyperinsulinism (2) · Myocardial Ischemia (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Barotrauma (1) · Behavior (1) · Coronary Disease (1)
Acarbose (1) · Air (1) · Arginine (1) · Atrasentan (1) · Eplerenone (1) · Exercise (1) · Febuxostat (1) · Oxygen (1) · Sildenafil Citrate (1) · Sodium Chloride (1) · Vildagliptin (1) · alagebrium (1) · darapladib (1) · enibarcimab (1) · glucuronyl glucosamine glycan sulfate (1)
Mayo Clinic (2) · Radboud University Medical Center (2) · Ain Shams University (1) · Centro Medico del Noroeste (1) · Dr. med. Mahir Karakas (1) · Göteborg University (1) · IRCCS San Raffaele (1) · Ruhr University of Bochum (1) · University of Erlangen-Nürnberg Medical School (1)
Germany (3) · Netherlands (2) · United States (2) · Italy (1) · Mexico (1) · Sweden (1)
Alejandro J Gonzalez-Ochoa, MD (1) · Alin Stirban, MD (1) · Amir Lerman, M.D. (1) · Amir Lerman, MD (1) · C.J. Tack, MD, PhD, Prof. of Diabetology (1) · Dan Ziegler, MD (1) · Mahir Karakas, MD, MBA (1) · Maria TE Hopman, MD, PhD (1) · Mikael Gennser, PhD (1) · PierMarco Piatti, MD (1) · Roland E Schmieder, Prof (1)
PMID 20733096, PMID 24400341, PMID 24485397, PMID 26385052, PMID 27306560, PMID 29052766, PMID 29268712, PMID 29306475, PMID 34895483
2005 (1), R01AG031750 (1), R01HL092954 (1)