Digestive System Neoplasms: Clinical Trials

4,982 trials for Digestive System Neoplasms, newest first

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2000 completed, 1176 unknown, 771 recruiting, 324 not yet recruiting. 4982 Not applicable.

By phase and status

PhaseTrialsStatus
Not applicable4982Completed 2000, Unknown 1176, Recruiting 771, Not yet recruiting 324, Terminated 286, Active not recruiting 214, Withdrawn 146, Enrolling by invitation 49, Suspended 16

Follow Digestive System Neoplasms: new trials by email Literature Review of Digestive System Neoplasms trials Research Report on Digestive System Neoplasms

Trials (filtered) newest first · largest first

All 4,982 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Adaptive Neoadjuvant Therapy for Esophageal Cancer
Neoadjuvant concurrent chemoradiotherapy - Esophageal Carcinoma, Neoadjuvant Therapy
Not applicableEnrolling by invitationCancer Hospital Chinese Academy of Medical Science, Shenzhen Center432028-03-012025-05-25
Improving Clinic Delivery of HIV-related Anal Health Services
PEACHES 2.0 Implementation Strategies - HIV, Gonorrhea
Not applicableNot yet recruitingAlbert Einstein College of Medicine82028-02-012026-10-13
Endoscopic Ultrasound-Guided Pulsed Electric Field Ablation for the Treatment of Pancreatic Neoplasms
Clinical Intervention or Procedure, Electronic Health Record Review, Endoscopic Ultrasound-Guided Fine-Needle Aspiration of the Pancreas - Pancreatic Neoplasm, Pancreatic Neuroendocrine Tumor
Not applicableEnrolling by invitationOhio State University Comprehensive Cancer Center122027-10-012026-10-13
Liver Transplantation for Non-Resectable Colorectal Liver Metastases Without Local Treatment Options
Liver transplantation - Colorectal Neoplasms, Liver Neoplasms
Not applicableNot yet recruitingCharite University, Berlin, Germany2602027-04-012026-09-10
Estimating The Rate Of Complete Ablation (A0) With The Use Of Biomechanical Deformable Image Registration
RayAblation - Liver Tumors
Not applicableNot yet recruitingM.D. Anderson Cancer Center2002027-04-012026-10-16
A Prospective Study of Concurrent Hyperthermia, Chemotherapy and Radiotherapy in Borderline and Locally Advanced Pancreatic Cancer (PANHEAT)
Hyperthermia plus neoadjuvant chemotherapy/radiotherapy Arm Description: Hyperthermia plus neoadjuvant chemotherapy (mFOLFIRINOX/nab Paclitaxel) followed by a) surgically resectable: Hyp - Borderline and Locally Advanced Pancreatic Cancer
Not applicableNot yet recruitingFernando Pessoa Canarias University602027-03-312026-09-24
Cancer Awareness Among Syrian Migrants
PMT-Based Cancer Screening Educational Intervention, PMT-Based Cancer Screening Education Program - Breast Cancer Screening, Cervical Cancer Screening
Not applicableNot yet recruitingToros University302027-03-092026-10-15
Life Expectancy-informed Colorectal Cancer Screening
Decision Tool - Colorectal Cancer Control and Prevention
Not applicableNot yet recruitingKathryn Martinez150002027-03-012026-10-20
A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients
Dietary Fiber, Enema Administration, Loperamide Hydrochloride - Low Anterior Resection Syndrome, Rectal Carcinoma
Not applicableRecruitingOhio State University Comprehensive Cancer Center802027-02-152026-10-06
ALDH2 Genetic Testing in East Asian Community
Genetic Test Results Return, Alcohol Flushing Education - Healthy Adult, Flushing
Not applicableNot yet recruitingNorthwestern University1002027-02-012026-10-28
OSCAR II STUDY - The ONCObind CTC Removal Study
ONCObind (Onco-Seraph) 100 Filter, Matched Controls - Pancreatic Ductal Adenocarcinoma (mPDAC), Metastatic Colorectal Carcinoma (mCRC)
Not applicableNot yet recruitingExThera Medical Corporation1202027-01-152026-04-17
TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE)
Music-assisted relaxation and imagery (MARI) - Surgery, Stomach Cancer
Not applicableNot yet recruitingCase Comprehensive Cancer Center202027-01-012026-08-05
A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.
Signatera Genome ultra-sensitive ctDNA blood test - NSCLC (Advanced Non-small Cell Lung Cancer), NSCLC (Non-small Cell Lung Cancer)
Not applicableNot yet recruitingNatera, Inc.9202027-01-012026-10-27
Feasibility Study of Huangqi Yangyuan Formula for Capecitabine-Induced Adverse Reactions in Advanced Colorectal Cancer
Capecitabine, Huangqi Yangyuan Formula (Chinese Herbal Decoction) - Advanced Colorectal Cancer, Capecitabine-Related Adverse Reaction
Not applicableNot yet recruitingHuanfang Fan352027-01-012026-11-03
Mind-Body Interventions for the Improvement of Quality of Life, Stress, and Sleep Quality Among Survivors of Breast, Prostate, Endometrial, or Colorectal Cancer
Media Intervention, Mind-body intervention, Meditation Therapy - Breast Cancer Stage I, Colorectal Cancer
Not applicableNot yet recruitingRoswell Park Cancer Institute302026-12-302026-11-05
RAPID for Unresectable Colorectal Liver Metastases
RAPID Procedure - Colorectal Liver Metastases (CRCLM), Colorectal Neoplasms
Not applicableNot yet recruitingSun Yat-Sen Memorial Hospital of Sun Yat-Sen University102026-12-302026-11-05
Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate Cancer
Aerobic Exercise, Biopsy Procedure, Biospecimen Collection - Colon Polyp, Colorectal Carcinoma
Not applicableRecruitingCity of Hope Medical Center302026-12-162026-08-28
A Decision Support Tool for Pancreatic Cancer Screening -Aim 2
Electronic Decision Support Tool - Pancreas Cancer
Not applicableNot yet recruitingUNC Lineberger Comprehensive Cancer Center402026-12-082026-11-05
Increasing Breast and Colorectal Cancer Screening in the Community
Chi gung: Stay Well, Live Well - Colorectal Neoplasms, Breast Neoplasms
Not applicableNot yet recruitingIcahn School of Medicine at Mount Sinai802026-12-012026-10-19
Preventing Early-Onset Colorectal Cancer in the VA
Patient intervention, PCP intervention - Colorectal Neoplasms, Mass Screening
Not applicableNot yet recruitingVA Office of Research and Development5362026-12-012026-10-02

Showing 20 of 4982. Sign in to see all of them.

Narrower conditions

Colorectal Neoplasms (1480)  ·  Pancreatic Neoplasms (692)  ·  Colonic Neoplasms (668)  ·  Carcinoma, Hepatocellular (651)  ·  Rectal Neoplasms (593)  ·  Stomach Neoplasms (576)  ·  Esophageal Neoplasms (391)  ·  Liver Neoplasms (293)  ·  Breast Neoplasms (290)  ·  Neoplasms (238)  ·  Gastrointestinal Neoplasms (224)  ·  Lung Neoplasms (181)  ·  Prostatic Neoplasms (140)  ·  Motor Activity (103)  ·  Colonic Polyps (90)

Broader conditions

Digestive System Diseases (4967)  ·  Neoplasms by Site (4959)  ·  Neoplasms (4744)  ·  Gastrointestinal Diseases (3567)  ·  Gastrointestinal Neoplasms (3344)  ·  Intestinal Diseases (2587)  ·  Intestinal Neoplasms (2553)  ·  Colonic Diseases (2096)  ·  Rectal Diseases (2030)  ·  Colorectal Neoplasms (1065)  ·  Neoplasms by Histologic Type (1049)  ·  Neoplasms, Glandular and Epithelial (954)  ·  Pathological Conditions, Signs and Symptoms (917)  ·  Liver Diseases (837)

Interventions

Blood Specimen Collection (65)  ·  Colonoscopy (65)  ·  Exercise (59)  ·  Standard of Care (58)  ·  Radiosurgery (44)  ·  Drug Therapy (42)  ·  Early Intervention, Educational (41)  ·  Methods (41)  ·  Radiotherapy (40)  ·  Surgical Procedures, Operative (39)  ·  Endoscopic Mucosal Resection (37)  ·  Oxaliplatin (36)  ·  Surveys and Questionnaires (35)  ·  Radiofrequency Ablation (34)  ·  Educational Status (31)

Sponsors

Seoul National University Hospital (68)  ·  Chinese University of Hong Kong (55)  ·  Fudan University (52)  ·  National Taiwan University Hospital (49)  ·  Sun Yat-sen University (49)  ·  Yonsei University (49)  ·  M.D. Anderson Cancer Center (45)  ·  Assistance Publique - Hôpitaux de Paris (39)  ·  Massachusetts General Hospital (38)  ·  RenJi Hospital (34)  ·  Memorial Sloan Kettering Cancer Center (30)  ·  Indiana University (28)  ·  Eastern Hepatobiliary Surgery Hospital (27)  ·  Ohio State University Comprehensive Cancer Center (27)  ·  Radboud University Medical Center (27)

Countries

United States (1230)  ·  China (963)  ·  France (333)  ·  South Korea (266)  ·  Italy (195)  ·  Canada (158)  ·  Spain (144)  ·  United Kingdom (143)  ·  Netherlands (137)  ·  Taiwan (115)  ·  Germany (112)  ·  Denmark (91)  ·  Sweden (81)  ·  Hong Kong (72)  ·  Belgium (71)

Top investigators

Jeong Min Lee, MD (13)  ·  Shivan Mehta, MD (10)  ·  Shyam Varadarajulu, MD (10)  ·  Douglas K Rex, MD (6)  ·  Lianhua Ye (6)  ·  Saleh K Saleh, MD (6)  ·  Carlos Robles-Medranda, MD FASGE (5)  ·  Chunling Jiang, PhD (5)  ·  Gloria Coronado, PhD (5)  ·  Ralf Kiesslich, Prof. (5)  ·  Simon SM Ng, MD (5)  ·  Virginia Sun (5)  ·  Yanbing Zhou (5)  ·  Erin Van Blarigan, ScD (4)  ·  Franco Carli, MD (4)

Results publications

PMID 30207593, PMID 35588252, PMID 37162250, PMID 23433878, PMID 26808342, PMID 28733257, PMID 37121331, PMID 15855973, PMID 21420083, PMID 24714327, PMID 29628281, PMID 33538338, PMID 33657038, PMID 37069476, PMID 40772525, PMID 40946805, PMID 42681563, PMID 14667750, PMID 15273542, PMID 15496622, PMID 15896435, PMID 16557381, PMID 18494054, PMID 18650514, PMID 19300227, PMID 20590903, PMID 20620274, PMID 21811939, PMID 21839994, PMID 22341257, PMID 22356323, PMID 22424438, PMID 22658389, PMID 22770982, PMID 22968066, PMID 23099728, PMID 23403142, PMID 23708720, PMID 24025632, PMID 24578254, PMID 24639382, PMID 25071111, PMID 25262100, PMID 25623323, PMID 25668428, PMID 25670810, PMID 25733127, PMID 25952085, PMID 26348120, PMID 26422979

NIH funding

P30CA033572 (12), P30CA014089 (10), P30CA015704 (8), 2019 (5), 2023 (5), 2025 (5), P30CA012197 (4), P30CA013330 (4), P30CA016672 (4), P30CA023108 (4), P30CA072720 (4), 2015 (3), P30CA006973 (3), P30CA068485 (3), R01CA207689 (3)