12 completed, 3 unknown, 1 active not recruiting, 1 recruiting. 17 Phase 2, 7 Phase 3, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 17 | Completed 12, Unknown 3, Active not recruiting 1, Recruiting 1 |
| Phase 3 | 7 | Completed 5, Recruiting 1, Unknown 1 |
| Phase 1 | 3 | Completed 3 |
Follow Diabetes Type 2: new trials by email Literature Review of Diabetes Type 2 trials Research Report on Diabetes Type 2
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Canagliflozin Targeting Vascular Inflammation Canagliflozin, Placebo - Diabetes Type 2, Coronary Artery Disease | Phase 2 / Phase 3 | Recruiting | Ottawa Heart Institute Research Corporation | 24 | 2024-11-15 | 2026-05-06 |
| Deploying Digital Prosthetic Interface Technology and Exercise in Dysvascular Amputees digital prosthetic interface technology - Diabetes Type 2, Amputation | Phase 2 | Active not recruiting | Spaulding Rehabilitation Hospital | 38 | 2023-12-20 | 2026-04-28 |
| Study to Evaluate MET409 Alone or in Combination With Empagliflozin in Patients With Type 2 Diabetes and NASH MET409 Active, MET409 Placebo, Empagliflozin - NASH, NASH - Nonalcoholic Steatohepatitis | Phase 2 | Unknown | Metacrine, Inc. | 120 | 2020-12-15 | 2021-06-01 |
| Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus ORMD-0801, Placebo Comparator - Diabetes Type 2 | Phase 2 | Completed | Oramed, Ltd. | 188 | 2015-07-27 | 2019-11-13 |
| The Efficacy of Bariatric Surgery Compared to Medical Therapy in Controlling Type2 Diabetes Mellitus in Patients With Non Morbid Obesity. Laparoscopic Sleeve Gastrectomy, Laparoscopic Roux-en-Y Gastric Bypass, Advanced Medical Therapy - Overweight, Diabetes Type 2 | Phase 2 / Phase 3 | Unknown | Hadassah Medical Organization | 76 | 2015-01-01 | 2019-03-01 |
| ARA290 in T2D (Effects of ARA 290, an Erythropoietin Analogue) in Prediabetes and Type 2 Diabetes) ARA 290 - Diabetes Type 2, Impaired Glucose Tolerance | Phase 2 | Unknown | Claes-Göran Östenson | 24 | 2013-10-01 | 2015-09-03 |
| A Study to Evaluate the Safety and Effectiveness of DM199 in Healthy Subjects and Type 2 Diabetes Patients DM199, Placebo - Diabetes Type 2 | Phase 1 / Phase 2 | Completed | DiaMedica Therapeutics Inc | 98 | 2013-04-01 | 2014-12-19 |
| Grain Exercise Trial - Whole Grain Versus no Grain With or Without Physiotherapy-promoted Exercise for Waist Loss Diet A, Diet B, Physiotherapy - Abdominal Obesity, Cardiovascular Diseases | Phase 2 / Phase 3 | Completed | Lund University | 105 | 2010-08-01 | 2017-06-20 |
| Safety Study of BMS-770767 in Subjects With Type 2 Diabetes BMS-770767, Placebo, Metformin - Diabetes Type 2 | Phase 2 | Completed | Bristol-Myers Squibb | 76 | 2010-05-01 | 2015-10-12 |
| A Study of OPC-262 in Patients With Type 2 Diabetes OPC-262 2.5 mg, OPC-262 5 mg, Placebo - Diabetes Type 2 | Phase 2 / Phase 3 | Completed | Kyowa Kirin Co., Ltd. | 255 | 2009-09-01 | 2014-01-08 |
| Study on DMMET-01 Versus Metformin on Improvement of Metabolic Control in Naive Type 2 Diabetes Patients DMMET-01, Metformin Hydrochloride - Diabetes Type 2 | Phase 2 / Phase 3 | Completed | Laboratorios Silanes S.A. de C.V. | 20 | 2009-03-01 | 2010-05-18 |
| Effect of DMMET-01 on Insulin Sensitivity in Naive Type 2 Diabetes Patients (CLAMP) DMMET-01, Placebo - Diabetes Type 2 | Phase 2 | Completed | Laboratorios Silanes S.A. de C.V. | 20 | 2008-07-01 | 2009-07-16 |
| Gait and Balance of Diabetes Type 2 Patients Physiotherapy - Diabetes Type 2 | Phase 2 / Phase 3 | Completed | University Hospital, Geneva | 71 | 2007-09-01 | 2010-01-14 |
| Efficacy of N-Acetylcysteine in Treatment of Overt Diabetic Nephropathy N-acetylcysteine - Diabetic Nephropathy, Chronic Kidney Disease | Phase 2 / Phase 3 | Completed | Shiraz University of Medical Sciences | 60 | 2007-01-01 | 2007-11-12 |
| Effects of Aliskiren, Irbesartan, and the Combination in Hypertensive Patients With Type 2 Diabetes and Diabetic Nephropathy Aliskiren - Diabetes Type 2 | Phase 1 / Phase 2 | Completed | Novartis | 24 | 2005-09-01 | 2007-11-29 |
| Time Course of the Antiproteinuric and Blood Pressure Lowering Effects After Initiation of Renin Inhibition With Aliskiren in Type 2 Diabetes Aliskiren - Diabetes Type 2 | Phase 1 / Phase 2 | Completed | Novartis | 18 | 2005-08-01 | 2016-09-23 |
| Clamp Study Comparing Inhalation of Technosphere®/Insulin in Smokers and Non-Smokers With Type 2 Diabetes Technosphere Insulin Inhalation Powder - Diabetes Type 2 | Phase 2 | Completed | Mannkind Corporation | 24 | 2004-08-01 | 2009-07-08 |
Diabetes Mellitus, Type 2 (17) · Diabetes Mellitus (5) · Glucose Intolerance (2) · Overweight (2) · Cardiovascular Diseases (1) · Coronary Artery Disease (1) · Diabetic Nephropathies (1) · Fatty Liver (1) · Hypertension (1) · Inflammation (1) · Insulin Resistance (1) · Non-alcoholic Fatty Liver Disease (1) · Obesity, Abdominal (1) · Proteinuria (1) · Renal Insufficiency, Chronic (1)
Endocrine System Diseases (17) · Glucose Metabolism Disorders (17) · Metabolic Diseases (17) · Nutritional and Metabolic Diseases (17) · Diabetes Mellitus (12) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (3) · Body Weight (2) · Hyperglycemia (2) · Nutrition Disorders (2) · Overnutrition (2) · Pathologic Processes (2) · Vascular Diseases (2) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1)
Metformin (2) · Physical Therapy Modalities (2) · aliskiren (2) · Acetylcysteine (1) · BMS-770767 (1) · Canagliflozin (1) · DM199 (1) · Exercise (1) · Insulin (1) · ORMD-0801 (1) · Whole Grains (1) · empagliflozin (1)
Laboratorios Silanes S.A. de C.V. (2) · Novartis (2) · Bristol-Myers Squibb (1) · Claes-Göran Östenson (1) · DiaMedica Therapeutics Inc (1) · Hadassah Medical Organization (1) · Kyowa Kirin Co., Ltd. (1) · Lund University (1) · Mannkind Corporation (1) · Metacrine, Inc. (1) · Oramed, Ltd. (1) · Ottawa Heart Institute Research Corporation (1) · Shiraz University of Medical Sciences (1) · Spaulding Rehabilitation Hospital (1) · University Hospital, Geneva (1)
United States (5) · Canada (2) · Denmark (2) · Mexico (2) · Sweden (2) · Australia (1) · Iran (1) · Israel (1) · Japan (1) · Netherlands (1) · South Korea (1) · Switzerland (1)
Hubert C Chen, MD (1) · Joel M Neutel, M.D. (1) · Kaatsuhisa Saito (1) · Kevin Boczar, MD (1) · Lara E Allet, MPtSc (1) · Manuel Gonzalez, PHD (1) · Paolo Bonato, PhD (1) · Salah Hadi, MD, MSc (1) · Staffan Lindeberg, MD PhD (1)
PMID 18579384, PMID 19138520, PMID 19587362, PMID 19900232, PMID 19921145, PMID 22974412, PMID 38639002, PMID 41039470
2009 (1), R44HD110327 (1)