259 completed, 71 unknown, 39 recruiting, 35 terminated. 105 Phase 2, 94 Phase 4, 86 Not applicable, 67 Phase 3, 17 Phase 1.
Follow Proteinuria: new trials by email Literature Review of Proteinuria trials Research Report on Proteinuria
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Relationship Between Insulin Dose and Complications in Type 1 Diabetes Routine/prescribed exogenous insulin dose - Diabetes Mellitus, Type 1 Diabetes, Cardiovascular Diseases (CVD) | Not yet recruiting | Rachel Miller | 80 | 2027-01-01 | 2026-11-02 | |
| A Study of the Efficacy and Safety of Zigakibart + Atrasentan in Adult Patients With Primary IgA Nephropathy zigakibart, atrasentan, Placebo - IgA Nephropathy (IgAN) | Phase 3 | Not yet recruiting | Novartis Pharmaceuticals | 340 | 2026-12-01 | 2026-09-30 |
| A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A Nephropathy JADE101, Placebo - IgA Nephropathy (IgAN) | Phase 3 | Recruiting | Jade Biosciences, Inc. | 480 | 2026-12-01 | 2026-11-03 |
| Obesity-Related Indices and Albuminuria in Type 2 Diabetes Obesity and Diabetes Mellitus, Type 2, Albuminuria | Not yet recruiting | Assiut University | 349 | 2026-11-10 | 2026-11-06 | |
| Optimizing Referral Pathways for Patients With Hematuria and Moderate-Severe Proteinuria Electronic Health Record alert - Referral and Consultation, Glomerulonephritis | Not applicable | Not yet recruiting | Geisinger Clinic | 1200 | 2026-11-01 | 2026-05-12 |
| An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Podocyte Diseases ManNAc - Focal Segmental Glomerulosclerosis, Minimal Change Disease | Phase 2 | Recruiting | National Human Genome Research Institute (NHGRI) | 30 | 2026-10-27 | 2026-10-30 |
| Study on the Efficacy and Safety of Initial Combination of Finerenone and Semaglutide in Non-Diabetic Adult Patients With Obesity Complicated by Chronic Kidney Disease With Albuminuria Finerenone, Finerenone Placebo, Semaglutide - Obesity; Chronic Kidney Disease; Albuminuria | Not applicable | Not yet recruiting | Peking University People's Hospital | 266 | 2026-09-01 | 2026-09-30 |
| Systemic Immune-Inflammation Index and Platelet Parameters in Diabetic Kidney Disease Diabetic Kidney Disease, Diabetic Nephropathies | Not yet recruiting | Assiut University | 120 | 2026-09-01 | 2026-08-19 | |
| Efficacy and Safety of Mycophenolate Mofetil in Refractory IgA Nephropathy Mycophenolate Mofetil (MMF), Prednisolon - IgA Nephropathy | Phase 2 | Not yet recruiting | Shaheed Suhrawardy Medical College and Hospital | 104 | 2026-09-01 | 2026-08-25 |
| RAndomized EHR-based Prescribing to Improve Disease-modifying Therapies for Cardio-Kidney-Metabolic Care (RAPID-CKM) Epic-Based Clinician Notification, Usual Care - Chronic Kidney Disease, Type 2 Diabetes | Not applicable | Enrolling by invitation | Baylor Research Institute | 600 | 2026-08-06 | 2026-10-15 |
| An Observational Post-Authorization Safety and Effectiveness Study of Ravulizumab in Adult Patients Aged 18 and Older Diagnosed With Paroxysmal Nocturnal Hemoglobinuria Using Multicenter Electronic Medical Records in South Korea Hemoglobinuria, Paroxysmal | Enrolling by invitation | Yonsei University | 78 | 2026-07-22 | 2026-11-06 | |
| Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria sparsentan, No sparsentan - Proteinuric Renal Disease, Proteinuric Kidney Disease | Phase 1 | Recruiting | Brigham and Women's Hospital | 20 | 2026-07-10 | 2026-07-30 |
| Finerenone for Regression of Albuminuria in Type 2 Diabetes With Chronic Kidney Disease Finerenone (BAY 94-8862), Placebo - Albuminuria, Type 2 Diabetes Mellitus (T2DM) | Phase 4 | Not yet recruiting | First Affiliated Hospital of Zhejiang University | 148 | 2026-07-01 | 2026-06-25 |
| Mesenchymal Stem Cell Exosomes Alone or Combined With HUVEC Exosomes in Non-Dialysis Chronic Kidney Disease Human Wharton's jelly mesenchymal stem cell (HWJ-MSC) exosomes, Human umbilical vein endothelial cell (HUVEC) exosomes, Placebo (0.9% sodium chloride) - Chronic Kidney Disease Stage 3, Chronic Kidney Disease Stage 4 | Phase 1 / Phase 2 | Completed | Nurhasan Agung Prabowo | 34 | 2026-07-01 | 2026-11-06 |
| A Study of Iptacopan in Korean Patients With Paroxysmal Nocturnal Hemoglobinuria or C3 Glomerulopathy Paroxysmal Nocturnal Hemoglobinuria, C3 Glomerulopathy | Recruiting | Novartis Pharmaceuticals | 21 | 2026-06-15 | 2026-06-26 | |
| A Study to Determine if BHV-1400 is Effective and Safe in Adults With IgA Nephropathy BHV-1400, Placebo - IgA Nephropathy | Phase 3 | Not yet recruiting | Biohaven Therapeutics Ltd. | 420 | 2026-06-01 | 2026-06-11 |
| A Study of JADE101 in Participants With Immunoglobulin A Nephropathy JADE101 - IgA Nephropathy | Phase 2 | Recruiting | Jade Biosciences, Inc. | 30 | 2026-05-19 | 2026-10-30 |
| Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Adolescents With Early Stages of Chronic Kidney Disease Dapagliflozin (10mg Tab), Placebo - Chronic Kidney Disease (Mild to Moderate), Albuminuria | Phase 4 | Recruiting | Centenario Hospital Miguel Hidalgo | 200 | 2026-04-23 | 2026-04-27 |
| Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin Empagliflozin (oral) - Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0), Albuminuria | Phase 2 | Recruiting | University of Illinois at Chicago | 20 | 2026-04-08 | 2026-05-19 |
| Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD) Finerenone, Semaglutide, Lotensin - Chronic Kidney Disease, Type 2 Diabetes | Phase 4 | Enrolling by invitation | Baylor Research Institute | 64 | 2026-04-08 | 2026-10-13 |
Showing 20 of 452. Sign in to see all of them.
Albuminuria (142) · Renal Insufficiency, Chronic (118) · Diabetic Nephropathies (74) · Hypertension (68) · Kidney Diseases (57) · Diabetes Mellitus, Type 2 (54) · Diabetes Mellitus (46) · Glomerulonephritis, IGA (40) · Nephrotic Syndrome (31) · Glomerulonephritis (23) · Glomerulosclerosis, Focal Segmental (23) · Renal Insufficiency (17) · Pre-Eclampsia (15) · Cardiovascular Diseases (14)
Female Urogenital Diseases (452) · Female Urogenital Diseases and Pregnancy Complications (452) · Male Urogenital Diseases (452) · Pathological Conditions, Signs and Symptoms (452) · Signs and Symptoms (452) · Urological Manifestations (452) · Urination Disorders (450) · Urogenital Diseases (450) · Urologic Diseases (447) · Kidney Diseases (242) · Pathologic Processes (154) · Endocrine System Diseases (138) · Disease Attributes (132) · Renal Insufficiency (129)
Losartan (22) · dapagliflozin (17) · Valsartan (11) · aliskiren (11) · finerenone (11) · empagliflozin (9) · Ramipril (8) · Adrenocorticotropic Hormone (7) · Rituximab (7) · Mycophenolic Acid (6) · iptacopan (6) · Amiloride (5) · Amlodipine (5) · Angiotensin-Converting Enzyme Inhibitors (5) · Atorvastatin (5)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (16) · Novartis Pharmaceuticals (11) · Medical University of Gdansk (8) · University Medical Center Groningen (7) · Alexion Pharmaceuticals, Inc. (6) · AstraZeneca (6) · Novartis (6) · Geisinger Clinic (5) · Mario Negri Institute for Pharmacological Research (5) · Steno Diabetes Center Copenhagen (5) · Children's Hospital of Fudan University (4) · Gulhane School of Medicine (4) · Mayo Clinic (4) · Nanjing University School of Medicine (4) · Odense University Hospital (4)
United States (167) · China (45) · Italy (40) · Canada (33) · Germany (31) · South Korea (31) · United Kingdom (30) · Spain (29) · Denmark (28) · France (28) · Netherlands (28) · Australia (23) · Taiwan (22) · Poland (21) · Turkey (Türkiye) (21)
Jeffrey B Kopp, M.D. (6) · Federico Grossi, MD, PhD (3) · Boleslaw Rutkowski, MD PhD (2) · Boye L. Jensen, Professor (2) · Cheuk-Chun Szeto, MD (2) · Choli Hartono, MD (2) · David G Warnock, MD (2) · Giovanni Montini, MD (2) · Hee Gyung Kang, Ph.D (2) · Ian H de Boer, MD, MS (2) · Itamar Raz, M.D. (2)
PMID 38299639, PMID 37916745, PMID 38682786, PMID 33107592, PMID 34778952, PMID 38018702, PMID 41805697, PMID 34164803, PMID 22978814, PMID 23059770, PMID 25660356, PMID 26032537, PMID 28756065, PMID 29937267, PMID 30999886, PMID 33782940, PMID 35224732, PMID 35675911, PMID 35869170, PMID 37254256, PMID 37466151, PMID 37772889, PMID 38770818, PMID 38864363, PMID 39082471, PMID 39513526, PMID 41630898, PMID 10093981, PMID 10189326, PMID 10218526, PMID 10371175, PMID 10546860, PMID 10563713, PMID 10634199, PMID 10676716, PMID 10789605, PMID 10971863, PMID 10988097, PMID 11071184, PMID 11188837, PMID 11216928, PMID 11262215, PMID 11366976, PMID 11399982, PMID 11532109, PMID 11719381, PMID 11722270, PMID 11737323, PMID 11740189, PMID 11807691
2016 (3), 2023 (3), 2017 (2), 2018 (2), 2019 (2), R21AT004490 (2), 1KL2RR025015-01 (1), 2004 (1), 2009 (1), 2015 (1), 2025 (1), 5RC2DK122397 (1), I01CX000264 (1), K23DK078774 (1), K23HL127100 (1)