99 completed, 25 recruiting, 24 unknown, 10 not yet recruiting. 94 Not applicable, 25 Phase 4, 19 Phase 3, 17 Phase 2, 6 Phase 1.
Follow Diabetes Type 2: new trials by email Literature Review of Diabetes Type 2 trials Research Report on Diabetes Type 2
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Glucose, Understanding, Integrated Digital Health, and Engagement (GUIDE) Study Integrated Digital Health (IDH) platform, Provider engagement - Diabetes, Diabetes Type 2 | Not applicable | Not yet recruiting | Yale University | 300 | 2027-03-01 | 2026-09-29 |
| Study Evaluating the Metabolic Effects of pulsENDO Therapy in Adults With Type 2 Diabetes pulsENDO Therapy - Diabetes Type 2, Diabetes | Not applicable | Not yet recruiting | Endogenex, Inc. | 320 | 2027-01-01 | 2026-08-18 |
| Effects of a Specialized Diabetes and Heart Clinic and Detection of Unrecognized Heart Failure in People With Type 2 Diabetes and Cardiovascular Disease Cardio-Metabolic Clinic - Cardiovascular Disease, Cardiometabolic Diseases | Not applicable | Recruiting | Odense University Hospital | 375 | 2026-10-20 | 2026-10-16 |
| An Online Lifestyle Program With an AI Lifestyle Coach and Continues Glucose Monitoring in Type 2 Diabetes. Lifestyle program, Lifestyle program + coach, Lifestyle program + coach + CGM - Diabetes Type 2 | Not applicable | Not yet recruiting | University of Twente | 160 | 2026-09-01 | 2026-06-25 |
| Enhancing Diabetes Care by Treating Insomnia Cognitive Behavioral Therapy for Insomnia, Usual care for diabetes management, Usual care for treatment of insomnia - Diabetes Type 2, Insomnia | Not applicable | Recruiting | Tulane University | 30 | 2026-09-01 | 2026-09-02 |
| Changing Outpatient Diabetes Care With Remote-Patient-Monitoring: A Real World Evidence Study With Pre-Post Comparison Remote-Patient-Monitoring (RPM) - Diabetes, Diabetes Care | Recruiting | Steno Diabetes Center Copenhagen | 12000 | 2026-06-10 | 2026-07-17 | |
| Effect of the Thrive AI Health App on Lifestyle Behaviors and Quality of Life App - Diabetes Type 2, Overweight or Obesity | Not applicable | Active not recruiting | Yale University | 20 | 2026-06-04 | 2026-10-27 |
| Perioperative Meditation Music Intervention in Patients With Type 2 Diabetes Undergoing Elective Surgery Meditation Music Group - Diabetes Type 2 | Not applicable | Recruiting | Istanbul Aydın University | 84 | 2026-06-03 | 2026-08-18 |
| Evaluate the Efficacy of an Oral Health Behavioral Intervention in People With Diabetes Diabetes Oral Health Program, Stannous Fluoride Dentifrice, Cetylpyridinium Chloride (CPC) and Zinc Lactate Mouthwash - Diabetes Type 2, Periodontal Disease | Phase 4 | Enrolling by invitation | Colgate Palmolive | 10000 | 2026-05-26 | 2026-09-03 |
| The Effect of Empagliflozin and Metformin on Oxidative Capacity and Microvascular Reactivity of Skeletal Muscle in Patients With Type 2 Diabetes Mellitus Empagliflozin (Jardiance®), Metformin, Synjardy® 12.5mg/1000mg film-coated tablets - Diabetes Type 2 | Phase 4 | Recruiting | University Medical Centre Ljubljana | 54 | 2026-04-16 | 2026-08-18 |
| CGM in Acute Ischemic Stroke Continuous Glucose Monitoring, Point-of-Care Testing - Acute Ischemic Stroke, Diabetes (DM) | Not applicable | Not yet recruiting | Isala | 82 | 2026-04-01 | 2026-04-06 |
| Pregnancy and Postpartum Breastfeeding Support for Patients With Gestational Diabetes Implementation mapping to develop a multilevel health system strategy for prevention of type 2 diabetes through targeted breastfeeding support for patients with gestational diabetes - Gestational Diabetes Mellitus (GDM), Diabetes Type 2 | Recruiting | University of California, Davis | 10 | 2026-03-23 | 2026-09-14 | |
| Digital Support for Reducing Salt Intake Among Patients With Diabetic Kidney Disease: Protocol for a Controlled Clinical Trial StenoFood App - Diabetes Type 2, Kidney Disease | Not applicable | Recruiting | Steno Diabetes Center Copenhagen | 104 | 2026-03-20 | 2026-03-20 |
| Continuous Glucose Monitoring (CGM) in an Underserved Population Continuous Glucose Monitoring (CGM) - Diabetes, Diabetes Mellitus | Not applicable | Recruiting | Tulane University | 50 | 2026-03-19 | 2026-05-05 |
| Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellitus and Obesity Dry Eye Disease (DED), Diabete Mellitus | Recruiting | Attikon Hospital | 100 | 2026-03-01 | 2026-06-02 | |
| Disentangling the Effect of Brain Insulin Resistance on Brain Health Diabetes Type 2, Diabetes Type 1 | Recruiting | Henrik Bo Wiberg Larsson | 150 | 2026-01-01 | 2026-02-25 | |
| FELLAShip to Better Health FELLAship - High Blood Glucose, High Cholesterol | Not applicable | Recruiting | University of Alabama at Birmingham | 90 | 2026-01-01 | 2026-01-22 |
| RAPIDE: The Feasibility of a Hybrid Care Model Hybrid care - Diabetes Type 2, Heart Failure | Not applicable | Not yet recruiting | Radboud University Medical Center | 180 | 2026-01-01 | 2025-09-12 |
| Effects of Henagliflozin Proline and Metformin XR on Body Composition in Geriatric Patients With Newly Diagnosed T2DM Henagliflozin Proline Tablets treatment, Metformin XR treatment - Diabetes Type 2 | Phase 4 | Not yet recruiting | Bin Lu | 116 | 2025-12-30 | 2026-01-07 |
| Magnetic Compression Anastomosis Procedure for Partial Jejuno-ileal Diversion: Evaluating the Feasibility of a Novel Endoscopic Magnetic Metabolic Interventional Therapy Magnetic Compression Anastomosis Procedure for Partial Jejuno-ileal Diversion - Diabetes Type 2, Bariatric Surgery | Not applicable | Recruiting | iIDEAS Group Holdings Limited | 5 | 2025-11-11 | 2026-01-20 |
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Diabetes Mellitus, Type 2 (175) · Diabetes Mellitus (49) · Obesity (26) · Insulin Resistance (9) · Overweight (9) · Hypertension (7) · Cardiovascular Diseases (6) · Renal Insufficiency, Chronic (5) · Cognitive Dysfunction (4) · Diabetes Mellitus, Type 1 (4) · Diabetic Nephropathies (4) · Glucose Intolerance (4) · Inflammation (4) · Motor Activity (4) · Non-alcoholic Fatty Liver Disease (4)
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Metformin (7) · Continuous Glucose Monitoring (5) · aliskiren (4) · Community Health Workers (3) · Dipeptidyl-Peptidase IV Inhibitors (3) · Exercise (3) · Sitagliptin Phosphate (3) · dapagliflozin (3) · empagliflozin (3) · semaglutide (3) · Cognitive Behavioral Therapy (2) · Insulin Detemir (2) · Physical Therapy Modalities (2) · Standard of Care (2) · Acetylcarnitine (1)
Yale University (4) · Mannkind Corporation (3) · Scripps Whittier Diabetes Institute (3) · Steno Diabetes Center Copenhagen (3) · University of North Carolina, Chapel Hill (3) · AstraZeneca (2) · Attikon Hospital (2) · Copenhagen University Hospital, Rigshospitalet (2) · Eli Lilly and Company (2) · Endogenex, Inc. (2) · Laboratorios Silanes S.A. de C.V. (2) · Lund University (2) · Mayo Clinic (2) · Meir Medical Center (2) · Novartis (2)
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PMID 10482972, PMID 10693087, PMID 10720604, PMID 11319655, PMID 11926784, PMID 12589096, PMID 15353531, PMID 15793206, PMID 15963399, PMID 16291066, PMID 16389125, PMID 16758177, PMID 17227586, PMID 17251278, PMID 17277315, PMID 17327309, PMID 18029463, PMID 18201203, PMID 18483158, PMID 18579384, PMID 18612117, PMID 19138520, PMID 19383872, PMID 19587362, PMID 19698185, PMID 19900232, PMID 19921145, PMID 20032779, PMID 20151996, PMID 20332511, PMID 20336198, PMID 20607462, PMID 20609970, PMID 20630062, PMID 20655123, PMID 20818193, PMID 20876709, PMID 21118565, PMID 21440872, PMID 21540423, PMID 21636159, PMID 21885793, PMID 21964170, PMID 21976274, PMID 21999640, PMID 22002075, PMID 22417277, PMID 22844471, PMID 22883509, PMID 22974412
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