279 completed, 65 unknown, 47 recruiting, 16 not yet recruiting. 440 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 440 | Completed 279, Unknown 65, Recruiting 47, Not yet recruiting 16, Terminated 13, Active not recruiting 12, Withdrawn 5, Suspended 2, Enrolling by invitation 1 |
Follow Depressive Symptoms: new trials by email Literature Review of Depressive Symptoms trials Research Report on Depressive Symptoms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Parenting-STAIR Modular for Military Fathers and OCONUS Families Parenting-STAIR Modular (PSTAIR-M), Treatment as Usual (TAU) - Depressive Symptoms, Emotional Depression | Not applicable | Not yet recruiting | New York University | 243 | 2026-12-01 | 2026-09-30 |
| e-Perinatal Butterfly: An Embedded Study for Parents Experiencing Perinatal Loss e-Perinatal Butterfly, Standard routine maternal care - Depressive Symptoms, Perinatal Loss | Not applicable | Not yet recruiting | University of Seville | 60 | 2026-11-02 | 2026-10-27 |
| Improving Student Mental Health Through a Universal Trauma-Informed Intervention RAP Club Delivered by a School Clinician, RAP Club Delivered by a Teacher, Standard Supervision - Anxiety Symptoms, Post-traumatic Stress Symptoms | Not applicable | Recruiting | Johns Hopkins Bloomberg School of Public Health | 960 | 2026-10-08 | 2026-10-19 |
| The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study OHDC-DC - Depression, Depressive Disorder | Not applicable | Recruiting | University of Wisconsin, Madison | 8 | 2026-10-01 | 2026-09-29 |
| Task-Shifting Adapted IPT-A for Youth Suicide Prevention Adapted Brief Interpersonal Psychotherapy for Adolescents (IPT-A LAZOS), Usual Community Center Services - Suicidal Ideation, Depressive Symptoms | Not applicable | Not yet recruiting | Boston College | 46 | 2026-10-01 | 2026-07-28 |
| Effects of Digital Detox on Mental Health in Young Adults App-based smartphone screen time restriction program - Anxiety Symptoms, Screen Time | Not applicable | Not yet recruiting | University of Bergen | 200 | 2026-09-21 | 2026-09-23 |
| AI Mental Health Tool vs. Psychoeducation Control Ash, Brief Therapist-Delivered Telehealth - Depressive Disorder, Depressive Symptoms | Not applicable | Active not recruiting | Slingshot AI | 500 | 2026-09-11 | 2026-09-25 |
| MindfulCityU-- A Mindfulness Mobile Application for Promoting University Students' Mental Health MindfulCityU, Waitlist control - Depressive Symptoms | Not applicable | Not yet recruiting | City University of Hong Kong | 120 | 2026-09-01 | 2026-04-24 |
| Cognitive Stimulation Program With Virtual Reality for Older Adults With Depressive Symptoms Cognitive stimulation program - Depressive Symptoms | Not applicable | Not yet recruiting | Grupo Lusófona | 60 | 2026-09-01 | 2026-07-17 |
| Nature Photography for Mental Well-Being and Nature Connectedness in Young Adults Nature-Based Mindful Photography, Human-Made Object Photography, Self-Guided Digital Stress Management Handbook - Psychological Distress, Depressive Symptoms | Not applicable | Not yet recruiting | Beijing Normal University | 300 | 2026-09-01 | 2026-09-09 |
| Effects of Exercise Intervention on Sleep Quality and Emotional Problems in College Students With Depressive Symptoms Archery Exercise, Non-exercise Control - Depressive Symptoms, Sleep Disturbance | Not applicable | Not yet recruiting | Capital University of Physical Education and Sports, China | 80 | 2026-08-01 | 2026-07-31 |
| Examining the Health Effects of NPOWER365 Among Black Same Gender Loving Men NPOWER365 HIV care intervention - Sexual and Gender Minorities, Social Stigma | Not applicable | Not yet recruiting | Rutgers, The State University of New Jersey | 350 | 2026-08-01 | 2026-06-10 |
| Using a School-Based Depression Literacy Psychoeducation Program With AI Chatbot to Improve Depression Literacy and Help-Seeking Among High School Students school-based depression literacy program - Depressive Symptoms, Mental Health (Depression) | Not applicable | Not yet recruiting | Chang Hsiu-Ju | 720 | 2026-08-01 | 2026-08-27 |
| Sleep More, Stress Less: 90-Day Trial of Neuralli Mood Neuralli Mood - Psychological Stress, Sleep Disturbance | Not applicable | Recruiting | Efforia, Inc | 100 | 2026-06-30 | 2026-07-21 |
| Metformin as Adjunct Therapy in Depression-obesity Comorbidity: Clinical and Genetic Evaluation Metformin, Antidepressant Therapy - Depression, Depressive Disorder | Not applicable | Recruiting | Riphah International University | 200 | 2026-06-17 | 2026-08-07 |
| Rise & Thrive: Community-Engagement Intervention for Stress and Depression in Youth. Rise Together: Community Engagement Intervention, Adulting 101: Life Skills - Depressive Symptoms, Allostatic Load | Not applicable | Recruiting | Ann & Robert H Lurie Children's Hospital of Chicago | 300 | 2026-06-09 | 2026-10-22 |
| Strength and Pain-Coping Through Resilience and Knowledge SPARK - Pain, Depressive Symptoms | Not applicable | Recruiting | Johns Hopkins University | 100 | 2026-06-01 | 2026-07-22 |
| Morning Activation to Improve Mood After Stroke Morning Activation Program, Health Education Program - Stroke, Depressive Symptoms | Not applicable | Recruiting | The Hong Kong Polytechnic University | 30 | 2026-05-15 | 2026-07-22 |
| Activating Social Resources in Psychotherapy-Seeking Individuals: Effectiveness and Timing of a Social Support Just-in-Time Adaptive Intervention Social Support Just-in-Time Adaptive Intervention - Loneliness, Social Support | Not applicable | Recruiting | University of Zurich | 120 | 2026-04-22 | 2026-04-30 |
| rTMS Combined With Aerobic Exercise for Older Adults With Mild Cognitive Impairment and Comorbid Depression Repetitive Transcranial Magnetic Stimulation, Aerobic Exercise, Sham Repetitive Transcranial Magnetic Stimulation - Mild Cognitive Impairment (MCI), Depressive Symptoms | Not applicable | Recruiting | Cheng-Hsin General Hospital | 45 | 2026-03-03 | 2026-06-17 |
Showing 20 of 440. Sign in to see all of them.
Depression (440) · Anxiety Disorders (168) · Psychological Well-Being (44) · Depressive Disorder (22) · Stress Disorders, Post-Traumatic (20) · Motor Activity (18) · Depressive Disorder, Major (17) · Emotional Regulation (17) · Stress, Psychological (16) · Sleep Initiation and Maintenance Disorders (15) · Mood Disorders (14) · Pain (12) · Caregiver Burden (9) · Neoplasms (9) · Stroke (9)
Behavior (439) · Behavioral Symptoms (439) · Mental Disorders (230) · Pathological Conditions, Signs and Symptoms (60) · Nervous System Diseases (59) · Personal Satisfaction (43) · Signs and Symptoms (40) · Social Behavior (36) · Mood Disorders (32) · Brain Diseases (30) · Central Nervous System Diseases (30) · Trauma and Stressor Related Disorders (27) · Neurologic Manifestations (26) · Pathologic Processes (26) · Stress Disorders, Traumatic (26)
Cognitive Behavioral Therapy (20) · Therapeutics (17) · Exercise (13) · Mindfulness-Based Cognitive Therapy (6) · Mindfulness (4) · Transcranial Magnetic Stimulation (4) · Cardiac Rehabilitation (3) · Cognitive Training (3) · Control Groups (3) · Methods (3) · Mindfulness-Based Stress Reduction (3) · Palliative Care (3) · Acceptance and Commitment Therapy (2) · Bupropion (2) · Case Management (2)
The University of Hong Kong (19) · University of Pennsylvania (8) · Johns Hopkins Bloomberg School of Public Health (6) · Johns Hopkins University (6) · The Hong Kong Polytechnic University (6) · Universitätsklinikum Hamburg-Eppendorf (6) · Wroclaw University of Health and Sport Sciences (6) · Koç University (5) · Linkoeping University (5) · University of Michigan (5) · Columbia University (4) · Medical University of South Carolina (4) · Universidad Miguel Hernandez de Elche (4) · Baylor College of Medicine (3) · Duke University (3)
United States (169) · Hong Kong (32) · Canada (23) · Spain (23) · Germany (16) · Sweden (14) · Turkey (Türkiye) (13) · Brazil (11) · China (10) · Italy (8) · Netherlands (7) · Poland (7) · Taiwan (7) · Chile (6) · Norway (6)
Gerhard Andersson, PhD (4) · Janiece L Taylor, PhD (3) · Jennifer Dahne, PhD (3) · Terry Lum, PhD (3) · Aarthi Padmanabhan, PhD (2) · Akash Wasil (2) · Courtney Millar, PhD (2) · David L Brody, MD, PhD (2) · Elan C Hope, PhD (2) · Gloria Wong, PhD (2) · Guiyun Xu, MD (2) · Guy W Fincham, MSc (2)
PMID 22642525, PMID 23046789, PMID 24960439, PMID 25245928, PMID 27771133, PMID 32402261, PMID 33182711, PMID 36706362, PMID 38094930, PMID 39574082, PMID 10634337, PMID 11001602, PMID 11485292, PMID 11779286, PMID 12040306, PMID 12467953, PMID 12785564, PMID 12837712, PMID 15950000, PMID 17004338, PMID 17130383, PMID 17324018, PMID 17328703, PMID 17826170, PMID 18213440, PMID 18522664, PMID 19329051, PMID 19531229, PMID 19803575, PMID 20183695, PMID 20462580, PMID 20708905, PMID 20887977, PMID 20959009, PMID 21190455, PMID 21939499, PMID 22013611, PMID 22104298, PMID 22352077, PMID 22579509, PMID 22897901, PMID 23046776, PMID 23200784, PMID 23325750, PMID 23649787, PMID 23720785, PMID 23916631, PMID 24009169, PMID 24175165, PMID 24836465
R01MD017610 (2), 2015 (1), 2016 (1), 2018 (1), 2023 (1), 3UG1CA189824-04S1 (1), 5RC1MD004563-02 (1), D43TW011302 (1), F31MH108280 (1), IK2CX002629 (1), K01AA027564 (1), K01HL141676 (1), K01MD013910 (1), K01MH110605 (1), K01MH118091 (1)