38 completed. 38 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 38 | Completed 38 |
Follow Cross Infection: new trials by email Literature Review of Cross Infection trials Research Report on Cross Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Outcomes of Inhaled Amikacin in Ventilator Associated Pneumonia Amikacin (Inhalation), Standard-of-Care Intravenous Antibiotics - Ventilator Associated Pneumonia ( VAP) | Phase 4 | Completed | Postgraduate Medical Institute, Lahore | 90 | 2024-01-05 | 2026-01-27 |
| Efficacy of Intravenous Amboxol Hydrochloride as an Adjunct Therapy for Severe Pneumonia in Critically Ill Patients Ambroxol Hydrochloride, Standard Therapy - Severe Pneumonia, Community-acquired Pneumonia | Phase 4 | Completed | National University of Malaysia | 32 | 2023-01-07 | 2023-12-27 |
| Tranexamic Acid to Reduce Infection After Gastrointestinal Surgery Tranexamic Acid, Placebos - Infection Wound, Gastrointestinal Complication | Phase 4 | Completed | Bayside Health | 3300 | 2022-05-18 | 2025-12-31 |
| Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults Zavicefta, Ceftazidime-Avibactam, Best Available Treatment - Urinary Tract Infection, Acute Pyelonephritis | Phase 4 | Completed | Pfizer | 60 | 2021-08-26 | 2024-10-21 |
| Efficacy and Safety of Ceftazidime-Avibactam (CAZ-AVI) in Chinese Participants With HAP (Including VAP) Zavicefta, Ceftazidime-Avibactam - Hospital-Acquired Pneumonia | Phase 4 | Completed | Pfizer | 235 | 2021-05-21 | 2024-09-19 |
| Effect of Statin Therapy on Mortality in Patients With Ventilator Associated Pneumonia Simvastatin - VAP - Ventilator Associated Pneumonia | Phase 4 | Completed | Ain Shams University | 161 | 2021-01-01 | 2022-02-09 |
| Demonstration Project on Health Care Worker Protection Against Hepatitis B in Kalulushi District Engerix-B - Hepatitis B Virus, Health Care Associated Infection | Phase 4 | Completed | Centre for Infectious Disease Research in Zambia | 641 | 2019-11-25 | 2026-08-10 |
| Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C Elbasvir 50 MG / Grazoprevir 100 MG [Zepatier] - Hepatitis C, Hemodialysis | Phase 4 | Completed | University of Pennsylvania | 6 | 2019-09-22 | 2021-12-15 |
| VITAL - VAP Prevention by BIP (Bactiguard Infection Protection) ETT Evac in Belgian ICUs ETTEvac, BIP ETTEvac - Ventilator-associated Pneumonia | Phase 4 | Completed | Bactiguard AB | 323 | 2018-10-31 | 2021-01-20 |
| GRam Stain-guided Antibiotics ChoicE for Ventilator-Associated Pneumonia (GRACE-VAP) Trial Gram stain-guided antibiotic choice, Guidelines-based antibiotics choice - Ventilator Associated Pneumonia | Phase 4 | Completed | Osaka General Medical Center | 206 | 2018-04-01 | 2022-09-21 |
| Mupirocin-Iodophor ICU Decolonization Swap Out Trial Arm 1. Routine Care (Mupirocin/CHG), Arm 2. Iodophor/CHG Decolonization - Staphylococcus Aureus | Phase 4 | Completed | Harvard Pilgrim Health Care | 353323 | 2017-05-01 | 2025-03-30 |
| 4% Chlorhexidine Gluconate Daily Bathing for Prevention of Hospital-acquired Infections in Intensive Care Settings 4% chlorhexidine gluconate soap-like solution, standard soap - Hospital Infection | Phase 4 | Completed | University Of Perugia | 449 | 2015-08-10 | 2018-08-21 |
| Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial L. rhamnosus GG - Probiotic, Placebo - Microcrystalline Cellulose - Ventilator Associated Pneumonia, Infections | Phase 4 | Completed | McMaster University | 2650 | 2015-06-01 | 2020-12-17 |
| Addition of Tobramycin Inhalation in the Treatment of Ventilator Associated Pneumonia tobramycin inhalation, placebo - Ventilator Associated Pneumonia (VAP) | Phase 4 | Completed | Erasmus Medical Center | 80 | 2015-03-01 | 2021-08-18 |
| BIP CVC Clinical Safety and Performance Study BIP CVC, Uncoated Standard CVC - Surgery, Central Line Associated Blood Stream Infections (CLABSI) | Phase 4 | Completed | Bactiguard AB | 36 | 2013-09-01 | 2016-06-23 |
| Common Canister Protocol for Inhaler Administration in Mechanically Ventilated Patients Common canister - Ventilator Associated Pneumonia | Phase 4 | Completed | Barnes-Jewish Hospital | 354 | 2013-06-01 | 2016-10-07 |
| Effect of Aerosolised Colistin in Ventilator Associated Pneumonia AS colistin and "imipenem", IV colistin " and "imipenem" ., AS colimycin (colistin) - Pneumonia, Ventilator-Associated | Phase 4 | Completed | Tunis University | 133 | 2013-04-01 | 2016-02-17 |
| Daily Chlorhexidine Bathing and Infection Rates in Critically-ill Patients Chlorhexidine bathing, Non-chlorhexidine bathing - Healthcare Associated Infections | Phase 4 | Completed | Vanderbilt University | 12000 | 2012-07-01 | 2014-01-10 |
| Pharmacodynamics Study of Imipenem in Patients With Ventilator Associated Pneumonia Imipenem - Ventilator Associated Pneumonia | Phase 4 | Completed | Prince of Songkla University | 8 | 2011-11-01 | 2017-09-20 |
| The Pharmacodynamics of Doripenem Between 4-hour and 1-hour Infusion in Patients With Ventilator-associated Pneumonia Doripenem - Ventilator-Associated Pneumonia | Phase 4 | Completed | Sutep Jaruratanasirikul | 12 | 2010-10-01 | 2011-11-09 |
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Pneumonia, Ventilator-Associated (24) · Healthcare-Associated Pneumonia (7) · Infections (4) · Critical Illness (3) · Intraabdominal Infections (3) · Pneumonia (3) · Urinary Tract Infections (3) · Sepsis (2) · Staphylococcal Infections (2) · Appendicitis (1) · Asthma (1) · Bacteremia (1) · Bacterial Infections (1) · Cholecystitis (1)
Disease Attributes (38) · Iatrogenic Disease (38) · Pathologic Processes (38) · Pathological Conditions, Signs and Symptoms (38) · Infections (34) · Lung Diseases (27) · Respiratory Tract Diseases (27) · Respiratory Tract Infections (27) · Pneumonia (24) · Healthcare-Associated Pneumonia (20) · Bacterial Infections and Mycoses (5) · Bacterial Infections (4) · Digestive System Diseases (3) · Female Urogenital Diseases (3)
Doripenem (3) · Imipenem (3) · Ceftriaxone (2) · Inhalation (2) · Linezolid (2) · Vancomycin (2) · avibactam, ceftazidime drug combination (2) · Ambroxol (1) · Amikacin (1) · Amoxicillin (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Arginine (1) · Cefotaxime (1) · Chlorhexidine (1) · Cilastatin, Imipenem Drug Combination (1)
Pfizer (4) · Sutep Jaruratanasirikul (3) · Bactiguard AB (2) · Hospital Universitario de Canarias (2) · Ain Shams University (1) · Assistance Publique - Hôpitaux de Paris (1) · Barnes-Jewish Hospital (1) · Bayside Health (1) · Centre Hospitalier Universitaire de Besancon (1) · Centre for Infectious Disease Research in Zambia (1) · Erasmus Medical Center (1) · Harvard Pilgrim Health Care (1) · Janssen Research & Development, LLC (1) · Janssen-Cilag Ltd.,Thailand (1) · King Edward Memorial Hospital (1)
United States (9) · Thailand (5) · France (4) · Malaysia (3) · Spain (3) · Argentina (2) · Belgium (2) · Brazil (2) · Canada (2) · Chile (2) · China (2) · Germany (2) · Greece (2) · Hong Kong (2) · India (2)
Sutep Jaruratanasirikul, MD (3) · Ahlem Trifi (1) · Apostolos Armaganidis, MD, PhD (1) · Benoit Misset, MD,Prof. (1) · Charis Roussos, MD, PhD (1) · Christof von Eiff, MD (1) · Deborah J Cook, MD (1) · Dilip R Karnad, MD,FACP,FRCP (1) · Evangelos J Giamarellos-Bourboulis, MD, PhD (1) · Helen Giamarellou, MD, PhD (1)
PMID 17872488, PMID 17954800, PMID 18626628, PMID 18707849, PMID 18719064, PMID 20670293, PMID 22422274, PMID 22483191, PMID 22952580, PMID 23778831, PMID 24011955, PMID 24279701, PMID 24636429, PMID 25602496, PMID 26196695, PMID 27033711, PMID 27044546, PMID 27143787, PMID 27600290, PMID 29741298, PMID 30267930, PMID 30409160, PMID 31227528, PMID 31783881, PMID 34546300, PMID 34871241, PMID 34981245, PMID 35394515, PMID 35724443, PMID 36682909, PMID 37815567, PMID 39731129, PMID 41013603, PMID 41248372, PMID 42829121
2014 (1)