54 recruiting, 20 not yet recruiting, 15 completed, 7 enrolling by invitation. 33 Not applicable, 11 Phase 2, 7 Phase 1, 6 Phase 4, 1 Early Phase 1.
Follow Crohn Disease (CD): new trials by email Literature Review of Crohn Disease (CD) trials Research Report on Crohn Disease (CD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission Adapted Physical Activity, Usual Care - Inflammatory Bowel Diseases (IBD), Fatigue | Not applicable | Not yet recruiting | University Hospital, Grenoble | 120 | 2027-06-01 | 2026-09-11 |
| R-3750 in Patients With Crohn's Disease R-3750, Placebo - Crohn Disease (CD) | Phase 1 | Not yet recruiting | Rise Therapeutics LLC | 40 | 2026-11-01 | 2026-08-28 |
| MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT) Antiphospholipid (aPL)-Positive, Rheumatic Arthritis | Not yet recruiting | Axiom Bioregistry | 5000 | 2026-10-18 | 2026-10-23 | |
| Ex Vivo Comparison Of Combination Versus Single Therapeutic Pathway Inhibition In Human Intestinal Mucosa From Patients With Inflammatory Bowel Disease Collection of 8 additional intestinal mucosal biopsies during standard-of-care endoscopy for subsequent ex vivo testing, Collection of an additional 2 mL blood sample - Ulcerative Colitis (UC), IBD (Inflammatory Bowel Disease) | Not applicable | Not yet recruiting | PhoenixLAB srls | 30 | 2026-10-01 | 2026-09-17 |
| Virtual hIStology of Crohn's Disease Ex-vivo Resected Anatomical Lesions Crohn Disease (CD) | Recruiting | Central Hospital, Nancy, France | 60 | 2026-09-25 | 2026-10-21 | |
| Characterization of Colorectal Dysplasic Lesions and Stratification of Their Evolving Risk in Inflammatory Bowel Disease Patients: a Prospective, Observational and Multicenter Study Crohn Disease (CD), Colitis Ulcerative | Not yet recruiting | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives | 800 | 2026-09-15 | 2026-07-22 | |
| INSIGHT-IBD Pragmatic Study Mirikizumab, Anti-TNF agents, anti-integrin antibodies - Ulcerative Colitis (UC), Crohn Disease (CD) | Phase 4 | Enrolling by invitation | Specialty Networks Research. | 400 | 2026-08-12 | 2026-10-29 |
| Prospective Evaluation of Flare Detection in IBD With Digital Biomarkers: Bring Your Own Device Study Wearing their own wearable device. - Inflammatory Bowel Disease (IBD), Ulcerative Colitis (UC) | Recruiting | Maastricht University Medical Center | 600 | 2026-08-04 | 2026-10-13 | |
| Impact of Ultra-Processed Food Reduction on Remission Duration in Pediatric Crohn's Disease Ultra-Processed Food Reduction Counseling, Standard Dietary Counseling - Crohn Disease (CD) | Not applicable | Recruiting | University Hospital, Motol | 124 | 2026-08-01 | 2026-10-20 |
| HB-adMSCs for the Treatment of Crohn's Disease HB-adMSCs - Hope Biosciences Adipose Derived Mesenchymal Stem Cells, 0.9% sodium chloride - Crohn Disease (CD) | Phase 2 | Recruiting | Hope Biosciences Research Foundation | 46 | 2026-07-14 | 2026-08-06 |
| Optimal Care With Guselkumab in Crohn's Disease / OPTIM Study A Prospective Open Label Interventional, Multicenter Study Guselkumab - Crohn Disease (CD), Intensification | Phase 4 | Recruiting | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives | 210 | 2026-06-18 | 2026-06-30 |
| VR Therapies for IBD Distraction VR, VR/AI CBT - Inflammatory Bowel Disease (IBD), Ulcerative Colitis (UC) | Not applicable | Not yet recruiting | Brennan Spiegel | 76 | 2026-06-01 | 2026-05-15 |
| DB-3Q for the Treatment of Medically Refractory Crohn's Disease DB-3Q, Placebo - Crohn Disease (CD) | Phase 2 | Recruiting | Direct Biologics, LLC | 36 | 2026-06-01 | 2026-09-01 |
| Efficacy of MIrikizumab to Achieve Transmural Healing in patiENTs With Crohn's Disease Mirikizumab - IV, Mirikizumab - SC - Crohn Disease (CD) | Phase 4 | Recruiting | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives | 75 | 2026-05-11 | 2026-05-26 |
| Clostridium Butyricum in Stenosing Crohn's Disease Clostridum Butyricum Capsule, Trehalose - Crohn Disease (CD) | Phase 1 / Phase 2 | Recruiting | San Giovanni Addolorata Hospital | 40 | 2026-05-08 | 2026-09-04 |
| Leucine-rich α2-glycoprotein Correlation With Clinical, Endoscopic and Histological Disease Activity of IBD in a EuRopean Context Leucine-rich α2-glycoprotein - Crohn Disease (CD), Ulcerative Colitis (UC) | Recruiting | Imelda GI Clinical Research Center | 100 | 2026-05-01 | 2026-06-02 | |
| Qualitative Exploration of Key Symptoms of Stricturing Crohn's Disease: Toward the Development of a Clinical Assessment Score. Semi-structured interview - Crohn Disease (CD) | Not yet recruiting | University Hospital, Grenoble | 15 | 2026-05-01 | 2026-05-20 | |
| Concordance Between Inflammatory Activity Assessed by Enteric MRI With and Without Intestinal Distension Product in Patients With Ileal Crohn's Disease. MRI - Crohn Disease (CD) | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 60 | 2026-04-22 | 2026-07-30 |
| Combining Nutritional Therapy and Anti-TNFα Treatment in Pediatric Patients With Crohn's Disease IFX + mCDED - Crohn Disease (CD), IBD (Inflammatory Bowel Disease) | Not applicable | Recruiting | University of British Columbia | 140 | 2026-04-22 | 2026-05-01 |
| Regenerative Endoscopy in Refractory Perianal Crohn's Disease Autologous Mechanical Tissue Stromal Vascular Fraction (tSVF) Injection - Crohn Disease (CD), Perianal Crohns Disease | Not applicable | Recruiting | Asian Institute of Gastroenterology, India | 50 | 2026-04-20 | 2026-06-17 |
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Crohn Disease (101) · Colitis, Ulcerative (51) · Inflammatory Bowel Diseases (40) · Irritable Bowel Syndrome (4) · Arthritis, Rheumatoid (3) · Psoriasis (3) · Anxiety Disorders (2) · Arthritis, Psoriatic (2) · Autism Spectrum Disorder (2) · Autoimmune Diseases (2) · Celiac Disease (2) · Colonic Neoplasms (2) · Colorectal Neoplasms (2) · Disease (2) · Fatigue (2)
Digestive System Diseases (101) · Gastroenteritis (101) · Gastrointestinal Diseases (101) · Intestinal Diseases (101) · Inflammatory Bowel Diseases (61) · Colonic Diseases (52) · Colitis (51) · Pathological Conditions, Signs and Symptoms (16) · Pathologic Processes (10) · Arthritis (7) · Joint Diseases (7) · Musculoskeletal Diseases (7) · Signs and Symptoms (6) · Behavior (5) · Connective Tissue Diseases (5)
Infliximab (5) · Adalimumab (3) · Ustekinumab (3) · Cholecalciferol (2) · Dietary Fiber (2) · guselkumab (2) · mirikizumab (2) · trichlorosucrose (2) · vedolizumab (2) · Blood Specimen Collection (1) · Budesonide (1) · Capsule Endoscopy (1) · Celecoxib (1) · Certolizumab Pegol (1) · Diet (1)
Sixth Affiliated Hospital, Sun Yat-sen University (5) · University Hospital, Clermont-Ferrand (4) · Asian Institute of Gastroenterology, India (3) · Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives (3) · Shmuel Kivity, MD (3) · University of Southern Denmark (3) · GLSMED Learning Health S.A. (2) · Imelda GI Clinical Research Center (2) · Pontificia Universidad Catolica de Chile (2) · TIDHI Innovation Inc. (2) · University Hospital, Grenoble (2) · University Medical Center Groningen (2) · Alimentiv Inc. (1) · American Laboratory Products Company (1) · Ana Maldonado-Contreras (1)
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