42 completed. 42 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 42 | Completed 42 |
Follow Coronary Heart Disease: new trials by email Literature Review of Coronary Heart Disease trials Research Report on Coronary Heart Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacodynamic and Short-term Effects of Half-dose Ticagrelor With or Without Aspirin vs DAPT From Day of PCI in CCS Aspirin 100 mg + clopidogrel (300 mg load → 75 mg daily) ×6 months, then aspirin monotherapy, Aspirin 100 mg + ticagrelor (90 mg load → 45 mg twice daily) ×6 months, then aspirin monotherapy, Ticagrelor (90 mg load → 45 mg twice daily) monotherapy; aspirin stopped at day 2 after randomisation; continued indefinitely - Coronary Heart Disease | Phase 4 | Completed | Kaohsiung Veterans General Hospital. | 54 | 2024-01-03 | 2026-09-14 |
| Efficacy and Safety of Shexiang Baoxin Pill in Patients With Ischemia With Non-Obstructive Coronary Artery Shexiang Baoxin pill（MUSKARDIA）, Placebo - Ischemia With Non-Obstructive Coronary Artery, Angina Pectoris | Phase 4 | Completed | Shanghai Hutchison Pharmaceuticals Limited | 240 | 2021-05-11 | 2024-04-23 |
| Bacillus Calmette-guérin Vaccination to Prevent COVID-19 BCG vaccine, Placebo - COVID-19, Virus Diseases | Phase 4 | Completed | Hellenic Institute for the Study of Sepsis | 301 | 2020-05-26 | 2021-05-11 |
| Effect of Empagliflozin on Ventricular Repolarization. Empagliflozin 25 MG - Diabetes Mellitus, Type 2, Coronary Heart Disease | Phase 4 | Completed | University of Sao Paulo | 90 | 2019-10-04 | 2024-05-08 |
| Arachidonic Acid-induced Platelet Aggregation Rate in Patients With Stable CAD Treated With Ticagrelor Monotherapy ticagrelor, Aspirin - Coronary Heart Disease | Phase 4 | Completed | Yong Huo | 70 | 2014-08-01 | 2016-06-21 |
| Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis- EXtended Antiplatelet Monotherapy (HOST-EXAM) Clopidogrel, Aspirin - Coronary Heart Disease | Phase 4 | Completed | Seoul National University Hospital | 5530 | 2014-02-01 | 2026-04-27 |
| Efficacy and Tolerability of Clopidogrel Resinate and Clopidogrel Bisulfate in Patients With Coronary Heart Disease (CHD) or CHD Equivalents aspirin + pregrel (Clopidogrel resinate), aspirin + placebo, aspirin + plavix (Clopidogrel bisulfate) - Coronary Heart Disease | Phase 4 | Completed | Seoul National University Hospital | 306 | 2013-11-01 | 2016-10-13 |
| Comparison of the Angiographic Result of the Orsiro Hybrid Stent With Resolute Integrity Stent Osiro Hybrid Drug-Eluting Stent, Resolute Integrity - Coronary Artery Disease, Coronary Heart Disease | Phase 4 | Completed | Seoul National University Bundang Hospital | 372 | 2013-09-01 | 2016-04-20 |
| Bare Metal Stent Versus Drug Coated Balloon With Provisional Stenting in Non-ST-Elevation Myocardial Infarction Stent, SeQuent(R) Please coated balloon - Coronary Heart Disease, NSTEMI | Phase 4 | Completed | University Hospital, Saarland | 210 | 2012-12-01 | 2023-05-06 |
| A Clinical Trials of Quick-Acting Heart Reliever for Moderate Coronary Stenosis Quick-Acting Heart Reliever, Isosorbide Dinitrate, Placebo of Isosorbide Dinitrate - Coronary Artery Stenosis, Coronary Heart Disease | Phase 4 | Completed | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | 120 | 2012-04-01 | 2014-08-05 |
| ORSIRO Stents Versus Xience PRIME Stents Assessed by Optical Coherence Tomography ORSIRO, XIENCE PRIME DES - Coronary Heart Disease | Phase 4 | Completed | Deutsches Herzzentrum Muenchen | 30 | 2012-04-01 | 2017-08-04 |
| Studies of Traditional Chinese Medicine Clinical Efficacy Evaluation Index Louxiangdan Tongxin granules, TCM granules placebo, Chixiangshen Tongxin granules - Coronary Heart Disease, Stable Angina Pectoris | Phase 4 | Completed | Liaoning University of Traditional Chinese Medicine | 480 | 2011-05-01 | 2012-01-02 |
| Niacin/Laropiprant and Endothelial Function Niacin/laropiprant, Placebo - Coronary Heart Disease | Phase 4 | Completed | University Medical Centre Ljubljana | 60 | 2010-09-01 | 2011-10-06 |
| Test Safety of Biodegradable and Permanent Limus-Eluting Stents Assessed by Optical Coherence Tomography Biodegradable polymer limus-eluting stents, Permanent polymer limus-eluting stent - Coronary Heart Disease | Phase 4 | Completed | Deutsches Herzzentrum Muenchen | 48 | 2010-04-01 | 2012-01-13 |
| Comparison of Generic and Original Formulation of Clopidogrel Plavix, Kardogrel - Coronary Heart Disease, Percutaneous Coronary Intervention | Phase 4 | Completed | University of Pecs | 75 | 2009-11-01 | 2013-01-29 |
| Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, or Famotidine omeprazole, 20mg twice daily, famotidine 40mg twice daily, pantoprazole 40mg once daily - Coronary Heart Disease, GI Bleeding | Phase 4 | Completed | Tel-Aviv Sourasky Medical Center | 63 | 2009-08-01 | 2016-07-07 |
| Varenicline Versus Transdermal Nicotine Patch for Smoking Cessation in Patients With Coronary Heart Disease Varenicline, Transdermal Nicotine Patch - Coronary Heart Disease | Phase 4 | Completed | Ottawa Heart Institute Research Corporation | 50 | 2009-04-01 | 2026-05-28 |
| Acarbose Cardiovascular Evaluation Trial Acarbose, Matching Placebo - Coronary Heart Disease, Acute Coronary Syndrome | Phase 4 | Completed | University of Oxford | 6526 | 2009-02-17 | 2017-07-25 |
| Persantin Preceding Elective PCI dipyridamole, placebo - Coronary Heart Disease, Percutaneous Transluminal Coronary Angioplasty | Phase 4 | Completed | Radboud University Medical Center | 30 | 2008-10-01 | 2015-10-30 |
| Efficacy and Safety of Hypertonic Sodium Lactate Solution Compared With 6% HES Solution in CABG Patients Hypertonic sodium lactate, 6% Hydroxy Ethyl Starch - Coronary Heart Disease | Phase 4 | Completed | Innogene Kalbiotech Pte. Ltd | 100 | 2008-07-01 | 2012-08-01 |
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Coronary Disease (42) · Atherosclerosis (4) · Diabetes Mellitus, Type 2 (4) · Angina Pectoris (3) · Angina, Stable (3) · Cardiovascular Diseases (3) · Hypercholesterolemia (3) · Acute Coronary Syndrome (2) · Diabetes Mellitus (2) · Dyslipidemias (2) · Hyperlipidemias (2) · Stroke (2) · Angina, Unstable (1) · Arrhythmias, Cardiac (1) · COVID-19 (1)
Myocardial Ischemia (42) · Vascular Diseases (42) · Heart Diseases (41) · Cardiovascular Diseases (39) · Metabolic Diseases (9) · Nutritional and Metabolic Diseases (9) · Pathological Conditions, Signs and Symptoms (9) · Lipid Metabolism Disorders (6) · Arterial Occlusive Diseases (5) · Arteriosclerosis (5) · Chest Pain (5) · Endocrine System Diseases (5) · Glucose Metabolism Disorders (5) · Neurologic Manifestations (5) · Pain (5)
Clopidogrel (7) · Aspirin (6) · Atorvastatin (4) · Ezetimibe (4) · Simvastatin (4) · Niacin (2) · Rosuvastatin Calcium (2) · Ticagrelor (2) · Acarbose (1) · BCG Vaccine (1) · Dipyridamole (1) · Drug-Eluting Stents (1) · Famotidine (1) · Fenofibrate (1) · Freeze Drying (1)
Deutsches Herzzentrum Muenchen (6) · Organon and Co (2) · Seoul National University Hospital (2) · University of Bern (2) · University of Sao Paulo (2) · AstraZeneca (1) · Centro de estudios en Cardiologia Intervencionista (1) · Guang'anmen Hospital of China Academy of Chinese Medical Sciences (1) · Hellenic Institute for the Study of Sepsis (1) · Innogene Kalbiotech Pte. Ltd (1) · Kaohsiung Veterans General Hospital. (1) · Kos Pharmaceuticals (1) · Liaoning University of Traditional Chinese Medicine (1) · National Heart Institute, Mexico (1) · Ottawa Heart Institute Research Corporation (1)
Germany (8) · China (5) · Switzerland (4) · United States (3) · Canada (2) · Italy (2) · Netherlands (2) · South Korea (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1) · Brazil (1) · France (1) · Greece (1)
Adnan Kastrati, MD (4) · Albert Schoemig, MD (3) · Stephan Windecker, MD (2) · Alan R. Shuldiner, MD (1) · Alessandro Del Maschio, Med. Doctor (1) · Alf-Aage R. Pettersen, M.D. (1) · Alfredo E Rodriguez, MD PhD FACC (1) · Ana Carolina M Gagliardi, nutritionist (1) · Andrew Pipe, MD (1) · Antonios Papadopoulos, MD, PhD (1) · Arne Westheim, M.D. Ph.D (1) · Bernhard Meier, MD (1) · Bruno Caramelli, MD, PhD (1)
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U01GM074518 (1)