5 completed, 4 recruiting, 4 unknown, 2 active not recruiting. 7 Phase 4, 5 Not applicable, 3 Phase 2, 3 Phase 3, 1 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Colchicine for the Reduction of Dependency and Vascular Events After an Acute Intracerebral Hemorrhage Colchicine 0.5 MG, Placebo - Colchicine, ICH - Intracerebral Hemorrhage | Phase 3 | Not yet recruiting | Population Health Research Institute | 1125 | 2026-09-30 | 2026-09-01 |
| Low-dose Colchicine for CABG Graft Failure Prevention Colchicine Pill, Placebo - CAD - Coronary Artery Disease, CABG | Not applicable | Not yet recruiting | Beijing Anzhen Hospital | 622 | 2026-09-01 | 2026-05-06 |
| Precision Colchicine Intervention to Suppress Atherosclerosis in TET2 Clonal Hematopoiesis Colchicine 0.5 mg orally once daily for 12 months., SoC therapy - Colchicine, Coronary Atherosclerosis Management | Phase 4 | Recruiting | Shenyang Northern Hospital | 120 | 2026-06-08 | 2026-10-01 |
| Colchicine's Effect on Inflammatory Markers Colchicine (Colcrys®), Placebo - Colchicine, Inflammation in Cardiac Surgery | Phase 4 | Recruiting | Ayesha Ather | 24 | 2026-01-16 | 2026-06-25 |
| Pilot Trial of Colchicine for Graft Failure in CABG Colchicine - CABG, Graft Failure | Phase 4 | Active not recruiting | Ruijin Hospital | 100 | 2025-12-29 | 2026-10-27 |
| Colchicine And Dialysis Patients; a Feasibility Study Colchicine 0.5 mg - Haemodialysis Patients, Colchicine | Not applicable | Recruiting | King's College London | 100 | 2025-04-10 | 2026-08-13 |
| The Effect of Colchicine on the Occurrence of Atrial Fibrillation After Cardiac Surgery NSAID, Colchicine 0.5 MG - Coronary Artery Disease, Atrial Fibrillation | Phase 4 | Completed | Tomsk Cardiology Research Institute | 140 | 2025-01-20 | 2026-09-30 |
| Colchicine in Patients With Heart Failure With Preserved Ejection Fraction and Inflammation Colchicine 0.5 MG Oral Tablet Once Daily - Heart Failure, Heart Failure With Preserved Ejection Fraction (HFPEF) | Phase 4 | Unknown | Dongying Zhang | 200 | 2024-10-31 | 2024-09-19 |
| Treatment of ACuTe Coronary Syndromes With Low-dose colchICine Colchicine Pill, Placebo - Acute Coronary Syndrome, Unstable Angina | Not applicable | Recruiting | Beijing Anzhen Hospital | 6574 | 2024-09-02 | 2024-10-30 |
| Efficacy and Safety of Colchicine After PCI Colchicine 0.5 mg, Colchicine 0.375 mg, Placebo - Coronary Heart Disease, Percutaneous Coronary Intervention | Phase 3 | Active not recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 8862 | 2024-07-09 | 2026-09-03 |
| Colchicine in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction Colchicine - HFpEF - Heart Failure With Preserved Ejection Fraction, Colchicine | Phase 1 / Phase 2 | Completed | I.M. Sechenov First Moscow State Medical University | 42 | 2022-12-15 | 2026-04-23 |
| Colchicine in HFpEF Colchicine, Placebo - Heart Failure, Inflammation | Phase 2 | Terminated | Montreal Heart Institute | 14 | 2022-06-17 | 2023-04-26 |
| Effect of Colchicine on MMP-9, NOX2, and TGF-β1 in Myocardial Infarct Colchicine, Percutaneous Coronary Intervention, Optimal medical treatment including statin, aspirin, P2Y12 inhibitor, and nitrate. - ST Elevation Myocardial Infarction, Colchicine | Phase 4 | Unknown | RSD dr. Soebandi | 148 | 2022-06-01 | 2023-04-11 |
| Low-dose Colchicine Inhibit Abdominal Aortic Aneurysm Growth Trial colchicine, Placebo - Colchicine, Abdominal Aortic Aneurysm | Not applicable | Unknown | Guangdong Provincial People's Hospital | 230 | 2022-06-01 | 2022-05-05 |
| Effect of Colchicine On Left Ventricle Function After Anterior Myocardial Infarction Assessed By Speckle Tracking Colchicine 0.5 mg Oral Tablet - Anterior MI, Colchicine | Phase 4 | Completed | Ain Shams University | 100 | 2022-02-01 | 2022-08-23 |
| Colchicine for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement Colchicine, Placebo - Transcatheter Aortic Valve Replacement, Atrial Fibrillation New Onset | Phase 3 | Completed | Insel Gruppe AG, University Hospital Bern | 120 | 2021-09-21 | 2026-06-03 |
| Study to Evaluate the Efficacy and Safety of Colchicine Tablets in Patients With COVID-19 Colchicine Tablets, Standard therapy - Covid19, Colchicine | Not applicable | Unknown | Shanghai Public Health Clinical Center | 60 | 2021-09-06 | 2021-09-09 |
| Dose-finding Study of Colchicine in Type 2 Diabetic Patients With Coronary Artery Disease Colchicine 0.5 mg, Colchicine 0.25 mg, Placebo - Colchicine, Diabetes Mellitus, Type 2 | Phase 2 | Completed | University of the Ryukyus | 54 | 2017-06-15 | 2022-05-12 |
Coronary Artery Disease (3) · Inflammation (3) · Heart Failure (2) · ST Elevation Myocardial Infarction (2) · Acute Coronary Syndrome (1) · Angina, Unstable (1) · Anterior Wall Myocardial Infarction (1) · Aortic Aneurysm, Abdominal (1) · Atrial Fibrillation (1) · COVID-19 (1) · Camurati-Engelmann Syndrome (1) · Cerebral Hemorrhage (1) · Coronary Disease (1) · Diabetes Mellitus, Type 2 (1) · Diarrhea (1)
Cardiovascular Diseases (11) · Heart Diseases (9) · Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Vascular Diseases (9) · Myocardial Ischemia (7) · Arterial Occlusive Diseases (3) · Arteriosclerosis (3) · Coronary Disease (3) · Infarction (3) · Ischemia (3) · Myocardial Infarction (3) · Necrosis (3) · Signs and Symptoms (2) · Aneurysm (1)
Colchicine (18) · Anti-Inflammatory Agents, Non-Steroidal (1) · Aspirin (1) · Nitrates (1) · Percutaneous Coronary Intervention (1) · Standard of Care (1) · Tablets (1)
Beijing Anzhen Hospital (2) · Ain Shams University (1) · Ayesha Ather (1) · Dongying Zhang (1) · Guangdong Provincial People's Hospital (1) · I.M. Sechenov First Moscow State Medical University (1) · Insel Gruppe AG, University Hospital Bern (1) · King's College London (1) · Montreal Heart Institute (1) · Population Health Research Institute (1) · RSD dr. Soebandi (1) · Ruijin Hospital (1) · Shanghai Public Health Clinical Center (1) · Shenyang Northern Hospital (1) · Tomsk Cardiology Research Institute (1)
China (7) · Russia (2) · Canada (1) · Egypt (1) · Indonesia (1) · Japan (1) · Switzerland (1) · United Kingdom (1) · United States (1)
Anastasia Shchendrygina (1) · Aristeidis Katsanos, MD (1) · Ashkan Shoamanesh, MD (1) · Dongying Zhang, MD. Ph.D. (1) · Dr Michael Robson (1) · Hongzhou Lu, PI (1) · Jianfang Luo, MD (1) · Mohamed Radwan, Master (1) · Nadia Bouabdallaoui, MD (1) · Qiang Zhao, MD (1) · Shinichiro Ueda, PhD (1) · Sibu Saha, MD (1) · Thomas Pilgrim, Prof. (1) · Xiang Cheng, MD (1) · Xiaoli Liu, PhD, MD (1)
PMID 32176778, PMID 32865380, PMID 33769515, PMID 37558377, PMID 37586845, PMID 39211951, PMID 40659682, PMID 40868251