8 completed, 8 unknown, 5 recruiting, 3 withdrawn. 20 Not applicable, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 20 | Completed 6, Unknown 5, Recruiting 4, Withdrawn 3, Active not recruiting 1, Terminated 1 |
| Early Phase 1 | 1 | Unknown 1 |
| Phase 1 | 1 | Not yet recruiting 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Cognitive Deficit: new trials by email Literature Review of Cognitive Deficit trials Research Report on Cognitive Deficit
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Minocycline In Neurocognitive Outcomes - Sickle Cell Disease Minocycline, Placebo - Sickle Cell Disease, Cognitive Impairment | Phase 1 | Not yet recruiting | University of Cincinnati | 30 | 2026-12-01 | 2026-11-03 |
| Prevalence of Mild Cognitive Impairment and Dementia in Patients Admitted to Non-neurological Rehabilitation Wards Cognitive and clinical screening, Extended neuropsychological assessment, Blood biomarker sampling and APOE genotyping - MCI, Mild Cognitive Impairment (MCI) | Not applicable | Recruiting | Fondazione Don Carlo Gnocchi ETS | 384 | 2026-01-20 | 2026-08-10 |
| Validation of the Lithuanian Version of the BNSS, CDSS, and the SCoRS Brief Negative Symptoms Scale, The Calgary Depression Scale for Schizophrenia, The Schizophrenia Cognition Rating Scale - Schizophrenia, Negative Symptoms in Schizophrenia | Recruiting | Lithuanian University of Health Sciences | 200 | 2023-12-11 | 2024-02-26 | |
| Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation Cognitive rehabilitation: CG group, Motor rehabilitation: MG group, Combined rehabilitation: CbG group - Rehabilitation, Multiple Sclerosis | Not applicable | Recruiting | Universita di Verona | 48 | 2023-07-05 | 2025-02-11 |
| Goal Management Training in Individuals With PTSD Goal Management Training (GMT) - PTSD, Post-traumatic Stress Disorder | Not applicable | Withdrawn | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2023-01-01 | 2023-02-08 | |
| Cognitive Rehabilitation in People With Metabolic Syndrome and Mild Cognitive Deficits Computerized cognitive program - Metabolic Syndrome, Cognitive Deficit | Not applicable | Completed | University of Ioannina | 50 | 2022-12-01 | 2025-07-02 |
| Validation of a Digital Self-Administered Cognitive Screening Tool: MoCA-XpressO MoCA-Xpresso - Cognitive Impairment, Cognitive Change | Not applicable | Unknown | MoCA Clinic and Institute | 100 | 2022-10-01 | 2023-05-30 |
| Studying the Effects of Brain Stimulation on Cognitive Control and Associated EEG in Human Subjects. Brain Stimulation - Cognitive Deficit | Not applicable | Active not recruiting | University of Cincinnati | 5 | 2022-06-20 | 2026-09-02 |
| Neurorehabilitation Through Hippotherapy of a Brain Stroke Hippotherapy, Conventional Neurorehabilitation - Cerebrovascular Accident, Neurorehabilitation | Not applicable | Unknown | Alliance Equiphoria | 52 | 2022-04-27 | 2024-07-31 |
| Neurocognitive Effects of Non-Invasive Near-Infrared Light Stimulation Transcranial photobiomodulation, Sham transcranial photobiomodulation - Attention Deficit Hyperactivity Disorder, Attention Difficulties | Not applicable | Recruiting | Francisco Gonzalez-Lima, PhD | 500 | 2022-02-09 | 2026-06-22 |
| Neurofeedback Effectiveness Trial in PTSD Neurofeedback - PTSD, Post-traumatic Stress Disorder | Not applicable | Withdrawn | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2022-02-01 | 2022-02-21 | |
| Gaming Apps Post-Stroke Mobile or tablet-based gaming applications, Stroke-related educational videos - Stroke, Cognitive Impairment | Not applicable | Withdrawn | Loma Linda University | 2021-12-01 | 2021-06-16 | |
| Evaluating the Efficacy of Cranial Electrotherapy Stimulation in Mitigating Anxiety-induced Cognitive Deficits Cranial Electrotherapy Stimulation, Sham Cranial Electrotherapy Stimulation - Anxiety, Cognitive Deficit | Not applicable | Completed | Tufts University | 124 | 2021-09-06 | 2025-04-10 |
| Effects of PEA-LUT on Frontal Lobe Functions and GABAergic Transmission in Long-Covid Patients palmitoylethanolamide co-ultramicronized with antioxidant flavonoid luteolin (PEA-LUT), Placebo - Fatigue, Cognitive Deficit | Not applicable | Completed | Department of Neurorehabilitation, Hospital of Vipiteno-Sterzing (BZ) Italy | 34 | 2021-08-16 | 2022-09-26 |
| Factors Predicting Outcome in Group Treatment of Alcohol Use Disorders (AUDs) Alcohol Use Disorder (AUD), Alcohol Abuse | Active not recruiting | The Hospital of Vestfold | 120 | 2021-02-01 | 2025-09-15 | |
| Effect of Vortioxetine on Cognitive Symptoms in Patients With Schizophrenia Vortioxetine - Cognitive Deficit | Early Phase 1 | Unknown | Alen Greš | 120 | 2020-07-01 | 2020-07-02 |
| Cognitive Intervention in Attention Deficit and Hyperactivity Disorder Cognitive Occupational Therapy - ADHD, Cognitive Deficit | Not applicable | Completed | Biruni University | 21 | 2020-06-15 | 2021-10-01 |
| Do Combinatorial Training Lead to Better Cognition and Daily Participation in TBI Persons With Cognitive Impairments aerobic exercise training, computerized cognitive training, guiding training - Trauma, Brain, Cognitive Deficit | Not applicable | Unknown | Chang Gung Memorial Hospital | 50 | 2020-06-03 | 2021-06-21 |
| Validation Study SCOBES-AR Cognitive Decline, Cognitive Deficit | Unknown | FH Joanneum Gesellschaft mbH | 300 | 2020-01-07 | 2022-08-09 | |
| Investigating the Use of Goal Management Therapy in Improving Cognitive Functioning in Public Safety Personnel With PTSD Goal Management Therapy, Psychosocial Education - Post Traumatic Stress Disorder, Cognitive Deficit | Not applicable | Unknown | Homewood Research Institute | 88 | 2019-11-01 | 2024-01-16 |
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Cognition Disorders (29) · Cognitive Dysfunction (11) · Stroke (4) · Stress Disorders, Post-Traumatic (3) · Attention Deficit Disorder with Hyperactivity (2) · Neurologic Manifestations (2) · Schizophrenia (2) · Alcoholism (1) · Anemia, Sickle Cell (1) · Anxiety Disorders (1) · Brain Injuries, Traumatic (1) · COVID-19 (1) · Caregiver Burden (1) · Cerebrovascular Disorders (1) · Delirium (1)
Neurocognitive Disorders (29) · Mental Disorders (28) · Nervous System Diseases (10) · Pathological Conditions, Signs and Symptoms (8) · Brain Diseases (6) · Central Nervous System Diseases (6) · Pathologic Processes (6) · Cardiovascular Diseases (4) · Signs and Symptoms (4) · Stress Disorders, Traumatic (4) · Trauma and Stressor Related Disorders (4) · Vascular Diseases (4) · Cerebrovascular Disorders (3) · Attention Deficit and Disruptive Behavior Disorders (2) · Neurodevelopmental Disorders (2)
Deep Brain Stimulation (1) · Equine-Assisted Therapy (1) · Exenatide (1) · Minocycline (1) · Neurofeedback (1) · Neuropsychological Tests (1) · Transcranial Direct Current Stimulation (1) · Vortioxetine (1)
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (2) · University of Cincinnati (2) · Alen Greš (1) · Alliance Equiphoria (1) · Azienda Ospedaliero-Universitaria di Parma (1) · Biruni University (1) · Centre for Addiction and Mental Health (1) · Chang Gung Memorial Hospital (1) · Department of Neurorehabilitation, Hospital of Vipiteno-Sterzing (BZ) Italy (1) · Dr. Stephen Choi (1) · FH Joanneum Gesellschaft mbH (1) · Fondazione Don Carlo Gnocchi ETS (1) · Francisco Gonzalez-Lima, PhD (1) · Homewood Research Institute (1) · Lithuanian University of Health Sciences (1)
United States (7) · Canada (5) · Italy (4) · Austria (1) · Croatia (1) · Denmark (1) · France (1) · Greece (1) · Lithuania (1) · Norway (1) · Switzerland (1) · Taiwan (1) · Turkey (Türkiye) (1)
Alessandra Dei Cas, MD (1) · Amine Karademir, Bachelor (1) · Andrew M Goldfine, MD (1) · Angela Golas, MD (1) · Benjamin M Hampstead, Ph.D. (1) · Bijan Najafi, PhD (1) · Ching-yi Wu, ScD (1) · Christopher Tarver, MD (1) · Cristina Polito (1) · Douglas W Barrett, Ph.D. (1) · Jens Egeland, Phd (1) · Leopold Saltuari, Md (1)
PMID 23993991, PMID 25854674, PMID 27444881, PMID 29252162, PMID 35535839, PMID 35625006, PMID 40086906, PMID 40457131, PMID 40458420, PMID 40555227, PMID 42449279
2015 (1)