25 completed, 5 unknown, 4 active not recruiting, 4 recruiting. 26 Not applicable, 3 Phase 2, 2 Phase 3, 1 Early Phase 1, 1 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Sage Extract Supplementation on Cognitive Function in Middle-Aged Men and Women SageXtra, Placebo - Cognitive Ability, General | Not applicable | Recruiting | ESM Technologies, LLC | 64 | 2026-02-15 | 2026-08-11 |
| Investigating the Effects of Beef Consumption on Cognitive and Brain Health Ready-to-eat beef in frozen, 5-oz packages, Ready-to-eat beef in frozen, 1-oz packages - Dietary Intervention, Dietary Proteins | Not applicable | Recruiting | University of Nebraska Lincoln | 240 | 2025-09-22 | 2026-05-29 |
| Investigating the Cognitive and Brain Health Benefits of Lean Pork Consumption Ready-to-eat lean pork in frozen, 5-oz packages - Dietary Intervention, Dietary Proteins | Not applicable | Withdrawn | University of Nebraska Lincoln | 2025-08-01 | 2025-12-26 | |
| The Effect of Nature and Game Based Activities on Older People Nature and Game Based Activities - Nature, Human, Older People | Not applicable | Unknown | Ondokuz Mayıs University | 52 | 2025-07-01 | 2025-06-12 |
| Project ICOPE Brazil: Assessment of Intrinsic Capacity in Brazilian Older Adults Intrinsic Capacity, Frailty | Not yet recruiting | University of Sao Paulo | 3838 | 2025-05-15 | 2025-05-13 | |
| Cognitive-Based Behavior Change Training Program Cognitive-Based Behavior Change Training Program - Behavioral Symptom, Preschool Child | Not applicable | Active not recruiting | Uskudar University | 44 | 2025-04-01 | 2025-05-22 |
| Investigating the Combined Effects of Intermittent Hypoxia and Exercise on Cognitive and Cerebral Function in Middle-Aged Adults Hypoxia, intermittent, physical exercise, Sham (No Treatment) hypoxia - Cognitive Ability, General, Brain Health | Not applicable | Not yet recruiting | Ayoub Boulares | 176 | 2025-04-01 | 2025-03-13 |
| Associations Between Dietary Intake and Cardiometabolic and Gut Microbiota Outcomes Cardiometabolic Risk Factors, Skin Condition | Active not recruiting | National University of Singapore | 240 | 2025-02-03 | 2026-08-05 | |
| Cilostazol-Ginkgo for Cognitive Function in Elderly Diabetes Cilostazol / Ginko Leaf Dried Ext., Placebo - Type 2 Diabets Mellitus, Cognitive Ability, General | Phase 3 | Recruiting | Seoul National University Bundang Hospital | 80 | 2025-01-01 | 2025-05-25 |
| ViewMind Atlas Cognition ViewMind Atlas™ - MCI, Cognitive Ability, General | Not applicable | Unknown | ViewMind | 270 | 2024-10-16 | 2024-12-24 |
| Red Blood Cell Transfusion in ECMO - A Feasibility Trial Red Blood Cell Transfusion - Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication | Not applicable | Recruiting | Australian and New Zealand Intensive Care Research Centre | 120 | 2023-09-20 | 2025-05-31 |
| Adolescent Probiotics in Stressed Adolescents Probiotics, placebo - Cognitive Ability, General, Immune System Function | Not applicable | Completed | University of Utah | 104 | 2022-05-03 | 2026-05-04 |
| Physical Activity and Disability Prevention in Postmenopausal Women Nordic walking, Strength training, Bungy Pump Exercises - Metabolic Syndrome, Fall Risk | Not applicable | Active not recruiting | Gdansk University of Physical Education and Sport | 72 | 2022-02-21 | 2025-01-17 |
| Neurodevelopment at 5.5 Years of Age in Children Who Received Infant Formula With Enriched Protein Fractions Enriched Protein Fractions, Protein Fraction - Cognitive Ability, General | Completed | Mead Johnson Nutrition | 116 | 2020-06-15 | 2021-12-16 | |
| Development, Usability and Feasibility Pilot Study of a Videogame Japi 1.0 - Mental Health Issue, Development, Child | Not applicable | Completed | Universidad de los Andes, Chile | 317 | 2018-03-01 | 2025-07-02 |
| Lifestyle Enriching Activities for Research in Neuroscience Intervention Trial: LEARNit Study Moderate-aerobic walking, Positron Emission Tomography (PET) scan, Healthy living education - Aging, Cognitive Ability, General | Not applicable | Completed | University of Southern California | 66 | 2016-08-21 | 2024-10-02 |
| Minnesota Healthy Brain Initiative Cognitive Ability, General | Completed | Hennepin Healthcare Research Institute | 690 | 2016-08-01 | 2020-10-19 | |
| Dietary Carbohydrate Consumption on Memory Performance and Mood in Children Meal Skipping, French fries, Mashed potatoes - Cognitive Ability, General | Not applicable | Completed | Toronto Metropolitan University | 22 | 2016-04-01 | 2017-08-09 |
| Classroom Standing Desks for Reducing Sitting Time in Children Intervention - Sedentary Lifestyle, Cognitive Ability, General | Not applicable | Completed | University of Lisbon | 49 | 2016-01-04 | 2017-05-03 |
| Evaluating the Role of Expectations in Response to Caffeine Consumption: An RCT Caffeine, Placebo - Caffeine, Affect | Not applicable | Completed | University of Alabama at Birmingham | 205 | 2015-06-01 | 2017-07-12 |
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PMID 20368481, PMID 20439790, PMID 21334562, PMID 21458777, PMID 21855742, PMID 21951520, PMID 22261206, PMID 22820124, PMID 22955125, PMID 23412942, PMID 23652274, PMID 24521364, PMID 24522447, PMID 24563822, PMID 25250670, PMID 25622303, PMID 26078250, PMID 26303560, PMID 26598472, PMID 26772171, PMID 26782858, PMID 26808332, PMID 27134133, PMID 27586134, PMID 27847486, PMID 27942207, PMID 28093823, PMID 28189300, PMID 28406674, PMID 28535707, PMID 28622956, PMID 29282881, PMID 29389015, PMID 30035305, PMID 30172435, PMID 30185958, PMID 30267045, PMID 30641478, PMID 30728929, PMID 30844465, PMID 31008902, PMID 31010126, PMID 31668885, PMID 31756405, PMID 32158386, PMID 33327936, PMID 33370132, PMID 33981943, PMID 34049394, PMID 34356226
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