20 completed, 18 unknown, 13 recruiting, 4 not yet recruiting. 32 Not applicable, 4 Phase 2, 4 Phase 4, 3 Phase 3, 1 Early Phase 1.
Follow Catheter Ablation: new trials by email Literature Review of Catheter Ablation trials Research Report on Catheter Ablation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Relaxin Therapy for Atrial Fibrillation Relaxin, Placebo - Atrial Fibrillation (AF), Arrhythmia | Phase 1 / Phase 2 | Not yet recruiting | Deeptankar DeMazumder | 208 | 2027-01-01 | 2026-01-22 |
| Pulsed Field Ablation for Paroxysmal Atrial Fibrillation: Clinical Efficacy and Left Atrial Function Protection Novel Pulsed Field Ablation System, Radiofrequency Ablation Catheter - Paroxysmal Atrial Fibrillation, Pulsed Field Ablation | Not applicable | Not yet recruiting | Tianjin Medical University General Hospital | 220 | 2026-10-01 | 2026-10-14 |
| Effect of Tirzepatide on Recurrence of Atrial Fibrillation After Catheter Ablation in Obese Patients Tirzepatide, Structured Lifestyle Intervention - Atrial Fibrillation, Obesity & Overweight | Phase 4 | Not yet recruiting | Yunlong Wang | 710 | 2026-09-01 | 2026-07-21 |
| Using Non-Invasive Mapping To Eliminate Structural Heart Disease Ventricular Tachycardia VIVO-assisted mapping - Ventricular Tachycardia (VT), Catheter Ablation | Not applicable | Recruiting | University of Warwick | 110 | 2026-08-15 | 2026-08-12 |
| Insulin Resistance as a Predictor of Pulsed Field Ablation Success in Atrial Fibrillation (HOMA-PULSE) Atrial Fibrillation, Insulin Resistance | Enrolling by invitation | Nemocnice AGEL Trinec-Podlesi a.s. | 120 | 2026-04-01 | 2026-04-27 | |
| Catheter Ablation Plus LAAO Versus Anticoagulation in Frail Elderly Patients With Atrial Fibrillation catheter ablation combined with LAAO (Left Atrial Appendage Occlusion), Atrial Fibrillation Radiofrequency Ablation Only - Atrial Fibrillation (AF), Stroke | Not applicable | Recruiting | Guangdong Provincial People's Hospital | 200 | 2026-03-24 | 2026-06-08 |
| Randomized Controlled Trial- Ablation Strategy for Paroxysmal Atrial Fibrillation - Trigger and Substrate Guided Wide Area Radiofrequency Ablation Compared to Pulsed Field Ablation Pulmonary Vein Isolation PVI-ONLY, CONTROL ARM, PVI-PLUS ARM, INTERVENTIONAL ARM - Atrial Fibrillation, Catheter Ablation | Not applicable | Recruiting | Ottawa Heart Institute Research Corporation | 556 | 2026-03-23 | 2026-09-03 |
| PROMBot-HSM-FA: Protocol for a Feasibility Study of a Chatbot Platform to Collect Patient-reported Outcomes After AF Ablation PROMBot-FA Chatbot-Supported Follow-Up, Standard Care (in control arm) - Atrial Fibrillation (AF), Catheter Ablation | Not applicable | Not yet recruiting | Ana Rita Londral, PhD | 76 | 2025-12-01 | 2025-11-26 |
| Substrate Remodelling and Targeted Ablation in AF Pulmonary vein reisolation, Ganglionic plexi ablation, Substrate ablation - Atrial Fibrillation (AF), Atrial Fibrillation Mechanisms | Not applicable | Recruiting | Barts & The London NHS Trust | 160 | 2025-11-07 | 2025-11-18 |
| Effects of Music During Atrial Fibrillation Ablation Under Conscious Sedation Music intervention, Control - Atrial Fibrillation (AF), Catheter Ablation | Not applicable | Recruiting | Shaoxing People's Hospital | 120 | 2025-07-06 | 2025-07-10 |
| Empiric Pulsed Field Pulmonary Vein Isolation During Atrial Tachycardia Ablation in Adults With Congenital Heart Disease Pulsed field ablation using a pentaspline ablation catheter - Atrial Fibrillation, Atrial Tachycardia | Not applicable | Withdrawn | Boston Children's Hospital | 2025-07-01 | 2026-07-14 | |
| Lattice-tip Versus Irrigated-tip Catheter for Linear Ablation of the Cavotricuspid Isthmus. A Multicenter, Randomized Study. CTI radiofrequency ablation. - Catheter Ablation | Not applicable | Completed | Mitera Hospital | 102 | 2025-06-16 | 2026-06-17 |
| Efficacy and Safety of Catheter abLation in patiEnts With seVere mitrAl regurgiTation and pErsistent Atrial Fibrillation: a Randomized Controlled Trial Catheter ablation plus medication, Medication, (ELEVATE-AF X) experimental group - Atrial Fibrillation (AF), Catheter Ablation | Not applicable | Recruiting | Beijing Anzhen Hospital | 146 | 2025-04-08 | 2026-03-13 |
| PulseSelect Based Pulmonary Vein Isolation and Ablation in Patients With Atrial Fibrillation EAM based Pulmonary Vein Isolation, Fluoro based pulmonary vein ablation - Atrial Fibrillation (AF), Catheter Ablation | Not applicable | Completed | Tsiachris Dimitrios | 40 | 2024-11-01 | 2025-09-25 |
| Cavo-Tricuspid Isthmus Block Durability After Pulsed Electric Field Ablation Catheter ablation of cavotricuspid isthmus using flower configuration of the Farapulse catheter, Catheter ablation of cavotricuspid isthmus using basket configuration of the Farapulse catheter - Flutter, Atrial, Cavotricuspid Isthmus Dependent Right Atrial Flutter | Not applicable | Unknown | Institute for Clinical and Experimental Medicine | 150 | 2024-09-16 | 2024-11-15 |
| Preventive Catheter Ablation for Ventricular arrhythmiaS in Patients With End-sTage Heart faiLure Catheter ablation, Medical therapy - Heart Failure, Arrhythmia, Ventricular | Not applicable | Recruiting | Heart and Diabetes Center North-Rhine Westfalia | 160 | 2024-09-13 | 2024-12-04 |
| Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF) Pulmonary vein isolation, DC Cardioversion, Implantable loop recorder - Persistent Atrial Fibrillation, Cardiac Arrhythmia | Not applicable | Recruiting | Barts & The London NHS Trust | 208 | 2024-07-26 | 2026-09-22 |
| Left Atrial Pressure-Guided Heart Failure Optimization During Atrial Fibrillation Ablation (LAP AF-HF) LAP-Triggered Heart Failure Optimization Pathway - Atrial Fibrillation (AF), Heart Failure | Active not recruiting | Medical College of Wisconsin | 300 | 2024-02-12 | 2026-05-19 | |
| Ganglion Plexus Ablation in Persistent Atrial Fibrillation ganglionated plexus ablation - Atrial Fibrillation, Persistent, Ganglionated Plexi | Not applicable | Unknown | Ning Zhou | 50 | 2024-01-01 | 2023-12-26 |
| Effect of Dapagliflozin on the Recurrence of Atrial Tachyarrhythmia in Patients Undergoing Catheter Ablation of Atrial Fibrillation Dapagliflozin 10 mg [Farxiga] - Atrial Fibrillation Recurrent, Catheter Ablation | Phase 2 / Phase 3 | Active not recruiting | Chang Gung Memorial Hospital | 196 | 2023-12-01 | 2023-12-21 |
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Atrial Fibrillation (44) · Arrhythmias, Cardiac (8) · Tachycardia, Ventricular (6) · Heart Failure (4) · Recurrence (3) · Ventricular Premature Complexes (3) · Atrial Flutter (2) · Autoimmune Diseases (2) · Cardiomyopathies (2) · Genetic Predisposition to Disease (2) · Myocarditis (2) · Pericarditis (2) · Stroke (2) · Agnosia (1) · Cicatrix (1)
Cardiovascular Diseases (58) · Pathologic Processes (58) · Pathological Conditions, Signs and Symptoms (58) · Heart Diseases (57) · Arrhythmias, Cardiac (50) · Cardiac Conduction System Disease (9) · Tachycardia (6) · Disease Attributes (5) · Cardiac Complexes, Premature (3) · Nervous System Diseases (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Cerebrovascular Disorders (2) · Disease Susceptibility (2) · Immune System Diseases (2)
Catheter Ablation (8) · Colchicine (2) · Electrocardiography (2) · Equipment and Supplies (2) · dapagliflozin (2) · Acupuncture Therapy (1) · Amiodarone (1) · Anti-Arrhythmia Agents (1) · Blood Specimen Collection (1) · Control Groups (1) · Dosage Forms (1) · Laser Speckle Contrast Imaging (1) · Magnetic Resonance Imaging (1) · Morphine (1) · Nutrition Therapy (1)
St. Vincent Cardiovascular Research Institute (3) · Barts & The London NHS Trust (2) · Beijing Anzhen Hospital (2) · Centro Medico Teknon (2) · Clinique Pasteur (2) · Erasmus Medical Center (2) · Robert Bosch Medical Center (2) · Scientific Institute San Raffaele (2) · Acutus Medical (1) · Ana Rita Londral, PhD (1) · Assistance Publique - Hôpitaux de Paris (1) · Boston Children's Hospital (1) · Caijie Shen (1) · Chang Gung Memorial Hospital (1) · Charles University, Czech Republic (1)
United States (10) · China (7) · Germany (7) · Spain (6) · France (5) · Italy (5) · United Kingdom (4) · Czechia (3) · Greece (3) · Belgium (2) · Canada (2) · Japan (2) · Netherlands (2) · Brazil (1) · Croatia (1)
Caihua Sang, MD (2) · Changsheng Ma, MD (2) · Paolo Della Bella, MD (2) · Parin J. Patel, MD (2) · Alexander A Ivanov, MD (1) · Alonso Pedrote, MD, PhD (1) · Antonio Berruezo, MD, PhD (1) · Arvindh Kanagasundram, M.D (1) · Bela Merkely, MD PhD DSc (1) · Bingjian Wang, MD (1) · Bryan Baranowski, MD (1) · Caijie Shen (1) · Carlos Escobar Cervantes, PhD (1) · Chenyang Jiang, MD (1)
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