7 not yet recruiting. 7 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Not yet recruiting 7 |
| Phase 1 | 2 | Not yet recruiting 2 |
Follow Cardiovascular Abnormalities: new trials by email Literature Review of Cardiovascular Abnormalities trials Research Report on Cardiovascular Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease Undergoing Surgical Repair End-expiratory lung volume optimization maneuver with PEEP titration, Standard Care (in control arm) - Congenital Heart Disease, Cardiopulmonary Bypass | Phase 1 / Phase 2 | Not yet recruiting | Charite University, Berlin, Germany | 80 | 2027-01-01 | 2026-10-15 |
| Pre-pubertal Low Dose Transdermal Estradiol in Turner Syndrome Estradiol transdermal patch 0.025mg/24 hours- 1/8th fractionated patch - Turner Syndrome, Primary Ovarian Insufficiency | Phase 2 | Not yet recruiting | Children's National Research Institute | 15 | 2026-09-01 | 2026-08-25 |
| Sota-ES - Sotatercept in Patients With Congenital Heart Disease and Eisenmenger´s Syndrome Sotatercept - Congenital Heart Disease (CHD), Eisenmenger Syndrome | Phase 2 | Not yet recruiting | Philipps University Marburg | 40 | 2026-09-01 | 2026-03-27 |
| A Study to Evaluate the Efficacy and Safety of Everolimus in Patients With Teratment-refractory Vascular Anomalies Everolimus - Vascular Malformations, Arteriovenous Malformations | Phase 2 | Not yet recruiting | Yonsei University | 67 | 2026-04-01 | 2026-03-17 |
| Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in Kids 2 mL SunButyrate-TG, Placebo, 4 mL SunButyrate-TG - Congenital Heart Disease (CHD) | Phase 1 / Phase 2 | Not yet recruiting | University of Nebraska | 105 | 2026-03-01 | 2026-02-24 |
| A Study Comparing Different Treatment Approaches for the Initiation of Puberty in Girls With Turner Syndrome Using a TRIFECTA-DARED Approach for Rare Diseases Oral estradiol valerate, Transdermal 17β estradiol - Turner Syndrome | Phase 2 | Not yet recruiting | Universiti Kebangsaan Malaysia Medical Centre | 24 | 2026-02-15 | 2026-02-02 |
| N-of-1 in ATS and MEPPC Flecainide, Flecainide + beta-blocker - Andersen Tawil Syndrome, Multifocal Ectopic Purkinje-related Premature Contractions | Phase 2 | Not yet recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 10 | 2025-03-01 | 2025-01-29 |
Heart Defects, Congenital (3) · Turner Syndrome (2) · Andersen Syndrome (1) · Arteriovenous Malformations (1) · Eisenmenger Complex (1) · Hemangioendothelioma (1) · Hemangioma (1) · Inflammation (1) · Lymphangioma (1) · Nevus (1) · Primary Ovarian Insufficiency (1) · Vascular Malformations (1)
Cardiovascular Diseases (7) · Congenital Abnormalities (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Heart Diseases (6) · Heart Defects, Congenital (3) · Chromosome Disorders (2) · Disorders of Sex Development (2) · Endocrine System Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genetic Diseases, Inborn (2) · Gonadal Disorders (2) · Gonadal Dysgenesis (2) · Male Urogenital Diseases (2)
ACE-011 (1) · Adrenergic beta-Antagonists (1) · Estradiol (1) · Everolimus (1) · Flecainide (1) · Standard of Care (1) · Sugars (1)
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Charite University, Berlin, Germany (1) · Children's National Research Institute (1) · Philipps University Marburg (1) · Universiti Kebangsaan Malaysia Medical Centre (1) · University of Nebraska (1) · Yonsei University (1)
United States (2) · Germany (1) · Malaysia (1)
Jeffrey Salomon, MD, MBA (1) · Stephan Rosenkranz, Prof. Dr. (1)