200 completed, 68 recruiting, 67 unknown, 26 terminated. 70 Not applicable, 69 Phase 2, 38 Phase 3, 34 Phase 4, 27 Phase 1.
Follow Disorders of Sex Development: new trials by email Literature Review of Disorders of Sex Development trials Research Report on Disorders of Sex Development
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Development of Healthcare Transition for Patients With Congenital Adrenal Hyperplasia exposure to healthcare transition protocol - Congenital Adrenal Hyperplasia | Not yet recruiting | University of Alabama at Birmingham | 40 | 2027-01-01 | 2026-10-14 | |
| Efficacy, Safety, Tolerability, and Pharmacokinetics of NBIP-01435 in Adult Participants With Classic Congenital Adrenal Hyperplasia (CAH) NBIP-01435 - Congenital Adrenal Hyperplasia | Phase 2 | Not yet recruiting | Neurocrine Biosciences | 36 | 2026-12-01 | 2026-09-30 |
| Hematological Profile in Children With Numerical Chromosomal Disorders Down Syndrome, Turner Syndrome | Not yet recruiting | Assiut University | 158 | 2026-11-02 | 2026-10-29 | |
| SEMAFORCRANIO : Multicenter, Double-blind, Parallel, Randomized Controlled Trial of the Efficacy of Semaglutide in Hypothalamic Obesity Secondary to Craniopharyngioma in Children Aged 12 to 17 Years Semaglutide (Wegovy) weekly injection, Placebo weekly Injection - Craniopharyngioma, Child | Phase 3 | Not yet recruiting | University Hospital, Angers | 50 | 2026-11-01 | 2026-09-29 |
| An Extension Trial of Asedebart in Participants With Congenital Adrenal Hyperplasia Asedebart - Adrenal Hyperplasia, Congenital | Phase 2 | Not yet recruiting | H. Lundbeck A/S | 45 | 2026-10-01 | 2026-10-05 |
| Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS Metyrapone 250 mg Oral Tablets, Placebo - Mild Autonomous Cortisol Secretion (MACS), Autonomous Cortisol Secretion (ACS) | Phase 2 | Recruiting | Mayo Clinic | 90 | 2026-10-01 | 2026-09-25 |
| Sexual Quality of Life in Female Patients With Lipodystrophy Syndromes or Turner's Syndrome: a Case-control Study Lipodystrophy Congenital Generalized, Lipodystrophy, Familial Partial | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1416 | 2026-10-01 | 2026-09-02 | |
| Pre-pubertal Low Dose Transdermal Estradiol in Turner Syndrome Estradiol transdermal patch 0.025mg/24 hours- 1/8th fractionated patch - Turner Syndrome, Primary Ovarian Insufficiency | Phase 2 | Not yet recruiting | Children's National Research Institute | 15 | 2026-09-01 | 2026-08-25 |
| Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS) Extended Serum Biomarker and Hormonal Panel, Liver Elastography with Controlled Attenuation Parameter, Targeted Genotyping of PNPLA3 rs738409 and HSD17B13 rs72613567 - Polycystic Ovary Syndrome (PCOS), Metabolic Dysfunction-Associated Steatotic Liver Disease | Not yet recruiting | Kayseri City Hospital | 150 | 2026-09-01 | 2026-07-30 | |
| Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) Beef+ - PCOS (Polycystic Ovary Syndrome), Obese Adolescents | Not applicable | Recruiting | Texas A&M University | 36 | 2026-09-01 | 2026-08-21 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of OMS1620 OMS1620, Placebo - Congenital Adrenal Hyperplasia (CAH) | Phase 1 | Not yet recruiting | OMass Therapeutics Australia Proprietary Ltd | 84 | 2026-09-01 | 2026-09-09 |
| Evaluation of Circadian Hormonal Balance: LC-MS/MS Measurement of Salivary and Serum Steroids in Patients With Congenital Adrenal Hyperplasia Congenital Adrenal Hyperplasia, Adrenal Insufficiency | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 50 | 2026-09-01 | 2026-07-21 | |
| Hydrocortisone Modified-release in Adults: Real-world Monitoring of Longitudinal Outcomes in coNgenital Adrenal hYperplasia CAH - Congenital Adrenal Hyperplasia | Not yet recruiting | IRCCS San Raffaele | 100 | 2026-07-31 | 2026-06-08 | |
| Evaluation of Serum Preptin Levels in Patients With Polycystic Ovary Syndrome Polycystic Ovary Syndrome (PCOS), Insulin Resistance | Not yet recruiting | GÜLDEN ANATACA | 60 | 2026-07-30 | 2026-07-30 | |
| Adrenal Diseases in the Population of Modena: A Clinical-Epidemiological Database of Patients Referred to the Adrenal Disorders Outpatient Clinic of the Clinical Unit of Endocrinology at the Modena University Hospital (AOU Modena) Cushing s Syndrome, Cushing Disease | Recruiting | Azienda Ospedaliero-Universitaria di Modena | 2000 | 2026-07-09 | 2026-11-05 | |
| Pediatric Congenital Adrenal Hyperplasia Management: Regret and Long-term Outcomes questionnaire - Classic Congenital Adrenal Hyperplasia, 21-Hydroxylase Deficiency | Recruiting | University Hospital, Lille | 40 | 2026-07-08 | 2026-08-24 | |
| The Efficacy and Safety of Inpegsomatropin Injection in Children With Turner Syndrome (TS) and Short Stature Inpegsomatropin-Injection, Givopegsomatropin Solution Injection - Turner Syndrome | Phase 3 | Recruiting | Xiamen Amoytop Biotech Co., Ltd. | 84 | 2026-07-05 | 2026-07-22 |
| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Crinecerfont in Participants With Classic Congenital Adrenal Hyperplasia (CAH) Who Are Less Than 4 Years Old Crinecerfont - Congenital Adrenal Hyperplasia | Phase 2 | Recruiting | Neurocrine Switzerland GmbH | 20 | 2026-07-01 | 2026-09-16 |
| Denys-Drash Syndrome and Risk of Post-transplant Lymphoproliferative Disorder Collection of data from the patient's medical file - Denys-Drash Syndrome | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 108 | 2026-06-01 | 2026-05-26 | |
| A Multiple Baseline Feasibility Trial of Social Management Training for People With Sex Chromosome Aneuploidies Social Management Training - Sex Chromosome Disorders | Phase 1 | Recruiting | University of Oslo | 30 | 2026-06-01 | 2026-07-22 |
Showing 20 of 415. Sign in to see all of them.
Turner Syndrome (124) · Adrenal Hyperplasia, Congenital (100) · Hyperandrogenism (81) · Polycystic Ovary Syndrome (59) · Klinefelter Syndrome (47) · Hypogonadism (30) · Kallmann Syndrome (23) · Sexual Infantilism (23) · Insulin Resistance (22) · Down Syndrome (16) · Obesity (16) · Genetic Diseases, Inborn (15) · Infertility (15) · Trisomy 13 Syndrome (14)
Female Urogenital Diseases and Pregnancy Complications (415) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (414) · Female Urogenital Diseases (414) · Male Urogenital Diseases (414) · Urogenital Diseases (414) · Gonadal Disorders (412) · Congenital Abnormalities (410) · Urogenital Abnormalities (410) · Endocrine System Diseases (406) · Genetic Diseases, Inborn (275) · Adrenogenital Syndrome (176) · Chromosome Disorders (163) · Nutritional and Metabolic Diseases (159) · Sex Chromosome Disorders of Sex Development (156)
Human Growth Hormone (24) · Hydrocortisone (13) · Metformin (12) · Estradiol (10) · Growth Hormone (10) · Blood Specimen Collection (8) · Gonadotropin-Releasing Hormone (8) · Progesterone (7) · Dexamethasone (6) · crinecerfont (6) · Estrogens (5) · Exenatide (5) · Chorionic Gonadotropin (4) · Ethinyl Estradiol (4) · Inositol (4)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (17) · University of Aarhus (17) · Assistance Publique - Hôpitaux de Paris (13) · Novo Nordisk A/S (12) · University of Virginia (11) · Massachusetts General Hospital (10) · University of Colorado, Denver (10) · Neurocrine UK Limited (8) · Rhythm Pharmaceuticals, Inc. (7) · Hospices Civils de Lyon (6) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (6) · Natera, Inc. (6) · Neurocrine Biosciences (6) · Spruce Biosciences (5) · Assiut University (4)
United States (187) · France (58) · Italy (34) · Denmark (30) · United Kingdom (28) · Germany (25) · Spain (25) · Netherlands (19) · Canada (15) · China (14) · Sweden (14) · Brazil (13) · Poland (13) · Belgium (12) · South Korea (11)
David Meeker, MD (6) · Stephanie B Seminara, MD (5) · Veronica Gomez-Lobo, M.D. (4) · Christine Burt Solorzano, MD (3) · Deborah P Merke, M.D. (3) · Shanlee M Davis, MD (3) · Shanlee M Davis, MD, PhD (3) · Alessandra Gambineri, MD (2) · Barbara Lippe, M.D. (2) · Christian Trolle, MD (2)
PMID 36978128, PMID 32034419, PMID 33527139, PMID 21209029, PMID 23643382, PMID 26091193, PMID 31132118, PMID 32542985, PMID 32870266, PMID 34146101, PMID 37318239, PMID 38828955, PMID 10417280, PMID 10518081, PMID 10599727, PMID 10599729, PMID 10634337, PMID 11476780, PMID 11531930, PMID 11739428, PMID 11788640, PMID 12213860, PMID 12466334, PMID 12629094, PMID 12785564, PMID 12788881, PMID 12820840, PMID 12837712, PMID 14573733, PMID 15613419, PMID 15784709, PMID 15900109, PMID 16606836, PMID 16757106, PMID 16757526, PMID 16764984, PMID 16801584, PMID 16814942, PMID 16895963, PMID 17074994, PMID 17130383, PMID 17334928, PMID 17535868, PMID 17536071, PMID 17761590, PMID 17826170, PMID 17875973, PMID 17959774, PMID 18064739, PMID 18073301
2023 (4), P50HD028934 (4), U54HD028138 (4), UL1TR001082 (4), 2009 (3), 2015 (2), U54HD028934 (2), 2004 (1), 2008 (1), 2017 (1), 2018 (1), 2019 (1), 268201000048C-5-0-1 (1), K01MH083045 (1), K12HD001259 (1)